Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | TKL/MLK/LZK protein kinase | 0.2092 | 0.9842 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2091 | 0.9836 | 0.9995 |
Brugia malayi | Protein kinase domain containing protein | 0.2092 | 0.9842 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.2088 | 0.982 | 0.9978 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0116 | 0.0289 | 0.5 |
Echinococcus multilocularis | protein kinase shaggy | 0.0116 | 0.0289 | 0.0293 |
Loa Loa (eye worm) | CMGC/GSK protein kinase | 0.0116 | 0.0289 | 0.0293 |
Echinococcus multilocularis | EGFP:Bcl2 fusion protein | 0.0705 | 0.3138 | 0.3189 |
Loa Loa (eye worm) | CMGC/GSK protein kinase | 0.0116 | 0.0289 | 0.0293 |
Giardia lamblia | Kinase, CMGC GSK | 0.0116 | 0.0289 | 0.5 |
Brugia malayi | intracellular kinase | 0.0116 | 0.0289 | 0.0293 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0116 | 0.0289 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.2091 | 0.9836 | 0.9995 |
Trypanosoma cruzi | glycogen synthase kinase 3, putative | 0.0116 | 0.0289 | 0.5 |
Leishmania major | glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 | 0.0116 | 0.0289 | 0.5 |
Echinococcus granulosus | glycogen synthase kinase 3 beta | 0.0116 | 0.0289 | 0.0293 |
Toxoplasma gondii | cell-cycle-associated protein kinase GSK, putative | 0.0116 | 0.0289 | 0.5 |
Echinococcus multilocularis | mitogen activated protein kinase kinase kinase | 0.2092 | 0.9842 | 1 |
Echinococcus granulosus | mitogen activated protein kinase kinase kinase | 0.2092 | 0.9842 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0116 | 0.0289 | 0.5 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0116 | 0.0289 | 0.5 |
Trypanosoma brucei | protein kinase, putative | 0.0116 | 0.0289 | 0.5 |
Giardia lamblia | Kinase, CMGC GSK | 0.0116 | 0.0289 | 0.5 |
Echinococcus granulosus | protein kinase shaggy | 0.0116 | 0.0289 | 0.0293 |
Echinococcus granulosus | EGFP:Bcl2 fusion protein | 0.0705 | 0.3138 | 0.3189 |
Schistosoma mansoni | glycogen synthase kinase 3-related (gsk3) (cmgc group III) | 0.0116 | 0.0289 | 0.0289 |
Plasmodium falciparum | glycogen synthase kinase 3 | 0.0116 | 0.0289 | 0.5 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.2088 | 0.982 | 0.9978 |
Plasmodium vivax | glycogen synthase kinase 3, putative | 0.0116 | 0.0289 | 0.5 |
Onchocerca volvulus | 0.0116 | 0.0289 | 0.5 | |
Echinococcus multilocularis | glycogen synthase kinase 3 beta | 0.0116 | 0.0289 | 0.0293 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0116 | 0.0289 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.