Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0483 | 0.1746 | 1 |
Chlamydia trachomatis | glutamyl-tRNA(Gln) amidotransferase subunit A | 0.0212 | 0 | 0.5 |
Echinococcus granulosus | sn1 specific diacylglycerol lipase beta | 0.0932 | 0.4647 | 0.4647 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.1761 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0932 | 0.4647 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0483 | 0.1746 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1761 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0932 | 0.4647 | 1 |
Brugia malayi | Lipase family protein | 0.0932 | 0.4647 | 0.4647 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.1761 | 1 | 1 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.1761 | 1 | 1 |
Trypanosoma brucei | lipase domain protein, putative | 0.0932 | 0.4647 | 1 |
Mycobacterium leprae | PROBABLE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE (SUBUNIT A) GATA (Glu-ADT SUBUNIT A) | 0.0212 | 0 | 0.5 |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.1761 | 1 | 1 |
Mycobacterium leprae | PROBABLE AMIDASE AMIC (AMINOHYDROLASE) | 0.0212 | 0 | 0.5 |
Schistosoma mansoni | amidase | 0.1761 | 1 | 1 |
Plasmodium vivax | glutamyl-tRNA(Gln) amidotransferase subunit A, putative | 0.0212 | 0 | 0.5 |
Plasmodium falciparum | glutamyl-tRNA(Gln) amidotransferase subunit A | 0.0212 | 0 | 0.5 |
Loa Loa (eye worm) | lipase | 0.0932 | 0.4647 | 0.4647 |
Wolbachia endosymbiont of Brugia malayi | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0212 | 0 | 0.5 |
Trichomonas vaginalis | lipase containing protein, putative | 0.0932 | 0.4647 | 0.5 |
Trypanosoma brucei | lipase domain protein, putative | 0.0932 | 0.4647 | 1 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.1761 | 1 | 1 |
Echinococcus multilocularis | sn1 specific diacylglycerol lipase beta | 0.0932 | 0.4647 | 0.4647 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0932 | 0.4647 | 1 |
Trichomonas vaginalis | lipase containing protein, putative | 0.0932 | 0.4647 | 0.5 |
Treponema pallidum | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0212 | 0 | 0.5 |
Onchocerca volvulus | 0.0932 | 0.4647 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.