Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0008 | 0.0095 | 0.0097 |
Onchocerca volvulus | 0.0011 | 0.0215 | 0.2229 | |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.0824 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0215 | 0.0219 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0011 | 0.0215 | 0.0215 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.007 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0215 | 0.0219 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0023 | 0.0023 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.007 | 0.5 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0444 | 0.0451 |
Schistosoma mansoni | coup transcription factor | 0.0011 | 0.0215 | 0.0215 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.1652 | 0.1652 |
Schistosoma mansoni | hypothetical protein | 0.02 | 0.7099 | 0.7099 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0215 | 0.0219 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0444 | 0.0451 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0444 | 0.0444 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0011 | 0.0215 | 0.0219 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0215 | 0.0219 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.007 | 0.5 |
Brugia malayi | CXXC zinc finger family protein | 0.0032 | 0.0966 | 0.0982 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0011 | 0.0215 | 0.0215 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0166 | 0.0169 |
Brugia malayi | nuclear receptor RXR | 0.0006 | 0.0023 | 0.0023 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0215 | 0.0219 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.007 | 0.5 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0444 | 0.0451 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0011 | 0.0215 | 0.0215 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0006 | 0.0023 | 0.0023 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.1032 | 0.1032 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0166 | 0.0169 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0055 | 0.1818 | 0.1848 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0444 | 0.0451 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0011 | 0.0215 | 0.0215 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.007 | 0.5 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0006 | 0.0023 | 0.0023 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0028 | 0.0824 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0215 | 0.0219 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0095 | 0.0097 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0215 | 0.0219 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0011 | 0.0215 | 0.2229 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0215 | 0.0219 |
Brugia malayi | nuclear hormone receptor | 0.0011 | 0.0215 | 0.0219 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0166 | 0.0169 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.007 | 0.5 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0011 | 0.0215 | 0.0219 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.007 | 0.5 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.0444 | 0.0451 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0215 | 0.0219 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0038 | 0.1182 | 0.1201 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0055 | 0.1818 | 0.1848 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.0215 | 0.0215 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0011 | 0.0215 | 0.0215 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0215 | 0.0219 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.1032 | 0.1032 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0215 | 0.0219 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0444 | 0.0444 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0215 | 0.0219 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0215 | 0.0219 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.006 | 0.2002 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0215 | 0.0219 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0215 | 0.0219 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0215 | 0.0219 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0006 | 0.0023 | 0.0023 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0824 | 0.0838 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0011 | 0.0215 | 0.0215 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0215 | 0.0219 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.1818 | 0.1848 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.0215 | 0.0219 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0067 | 0.2264 | 0.2264 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0215 | 0.0219 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0215 | 0.0219 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.007 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.0215 | 0.0215 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0215 | 0.0219 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0444 | 0.0451 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1182 | 0.1201 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0215 | 0.0219 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0006 | 0.0023 | 0.0023 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.007 | 0.5 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.007 | 0.5 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0095 | 0.0095 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0011 | 0.0215 | 0.0215 |
Leishmania major | hypothetical protein, conserved | 0.0028 | 0.0824 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0215 | 0.0219 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0011 | 0.0215 | 0.0219 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0444 | 0.0444 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0215 | 0.0219 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.1652 | 0.1652 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.007 | 0.5 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0011 | 0.0215 | 0.0219 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0023 | 0.0023 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.1652 | 0.1679 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.001 | 0.0161 | 0.0164 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.1182 | 0.1182 |
Schistosoma mansoni | hypothetical protein | 0.02 | 0.7099 | 0.7099 |
Schistosoma mansoni | nuclear hormone receptor | 0.0011 | 0.0215 | 0.0215 |
Brugia malayi | hypothetical protein | 0.0006 | 0.0023 | 0.0023 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.007 | 0.5 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.0444 | 0.0451 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.1652 | 0.1652 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0215 | 0.0219 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0006 | 0.0023 | 0.0023 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0011 | 0.0215 | 0.0219 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.007 | 0.5 |
Brugia malayi | steroid hormone receptor | 0.0011 | 0.0215 | 0.0219 |
Brugia malayi | Protein kinase domain containing protein | 0.0275 | 0.9837 | 1 |
Echinococcus multilocularis | geminin | 0.02 | 0.7099 | 0.7216 |
Loa Loa (eye worm) | hypothetical protein | 0.0275 | 0.9837 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0023 | 0.0023 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0264 | 0.0264 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0006 | 0.0023 | 0.0023 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0055 | 0.1818 | 0.1848 |
Brugia malayi | nuclear receptor NHR-88 | 0.0011 | 0.0215 | 0.0219 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0215 | 0.0219 |
Echinococcus granulosus | geminin | 0.02 | 0.7099 | 0.7216 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0215 | 0.0219 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0012 | 0.0264 | 0.0268 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0215 | 0.0219 |
Loa Loa (eye worm) | TKL/MLK/LZK protein kinase | 0.0275 | 0.9837 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0966 | 0.0966 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.0824 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0215 | 0.0219 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.1652 | 0.1679 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0011 | 0.0215 | 0.0219 |
Onchocerca volvulus | 0.0032 | 0.0966 | 1 | |
Echinococcus granulosus | mitogen activated protein kinase kinase kinase | 0.0275 | 0.9837 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0824 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0444 | 0.0451 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.007 | 0.5 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0011 | 0.0215 | 0.0219 |
Echinococcus granulosus | cpg binding protein | 0.0034 | 0.1032 | 0.1049 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0006 | 0.0023 | 0.0023 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0011 | 0.0215 | 0.0215 |
Brugia malayi | hypothetical protein | 0.0006 | 0.0023 | 0.0023 |
Echinococcus multilocularis | cpg binding protein | 0.0034 | 0.1032 | 0.1049 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0215 | 0.0219 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0011 | 0.0215 | 0.0219 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0011 | 0.0215 | 0.0215 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0011 | 0.0215 | 0.2229 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0824 | 0.0838 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0215 | 0.0219 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0011 | 0.0215 | 0.0219 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0011 | 0.0215 | 0.2229 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.007 | 0.5 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0011 | 0.0215 | 0.0219 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0032 | 0.0966 | 0.0982 |
Echinococcus granulosus | FTZ F1 alpha | 0.0011 | 0.0215 | 0.0219 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0011 | 0.0215 | 0.0219 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.007 | 0.5 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0008 | 0.0095 | 0.0097 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0215 | 0.0219 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0215 | 0.0219 |
Loa Loa (eye worm) | hypothetical protein | 0.0275 | 0.9837 | 1 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0012 | 0.0264 | 0.0268 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0215 | 0.0219 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0444 | 0.0451 |
Brugia malayi | ecdysteroid receptor | 0.0011 | 0.0215 | 0.0219 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0215 | 0.0219 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0215 | 0.0219 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0444 | 0.0444 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.1652 | 0.1679 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.007 | 0.5 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.005 | 0.1652 | 0.1679 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0023 | 0.0023 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0464 | 0.0472 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0011 | 0.0215 | 0.0219 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0215 | 0.0219 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0028 | 0.0824 | 0.5 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0824 | 0.5 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0095 | 0.0097 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 0.1652 | 0.1679 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.1652 | 0.1679 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0444 | 0.0451 |
Echinococcus multilocularis | mitogen activated protein kinase kinase kinase | 0.0275 | 0.9837 | 1 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.007 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.