Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0001 | 0.0000037143 | 0.013 |
Echinococcus granulosus | kelch protein 3 | 0.0001 | 0.0003 | 0.0003 |
Brugia malayi | Kelch-like protein X | 0.0001 | 0.0003 | 1 |
Echinococcus multilocularis | kelch protein 12 | 0.0001 | 0.0003 | 0.0003 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0001 | 0 | 0.5 |
Brugia malayi | BTB/POZ domain containing protein 9 | 0.0001 | 0.0000037143 | 0.013 |
Trichomonas vaginalis | multiple ankyrin repeats single kh domain protein, putative | 0.0001 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0001 | 0.0003 | 0.0003 |
Echinococcus multilocularis | kelch protein 3 | 0.0001 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | Btbd7 protein | 0.0001 | 0.0000037143 | 0.013 |
Loa Loa (eye worm) | hypothetical protein | 0.0001 | 0.0000037143 | 0.013 |
Brugia malayi | BTB/POZ domain containing protein | 0.0001 | 0.0000037143 | 0.013 |
Onchocerca volvulus | 0.0001 | 0.0000037143 | 1 | |
Brugia malayi | Zinc finger, C2H2 type family protein | 0.0001 | 0.0000037143 | 0.013 |
Loa Loa (eye worm) | BTB/POZ domain-containing protein 9 | 0.0001 | 0.0000037143 | 0.013 |
Schistosoma mansoni | hypothetical protein | 0.0001 | 0.0003 | 0.0003 |
Brugia malayi | BTB/POZ domain containing protein | 0.0001 | 0.0000037143 | 0.013 |
Echinococcus granulosus | kelch ECH associated protein 1 like | 0.0187 | 0.9972 | 1 |
Echinococcus multilocularis | ectoderm neural cortex protein 1 | 0.0001 | 0.0003 | 0.0003 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0001 | 0 | 0.5 |
Brugia malayi | Armadillo/beta-catenin-like repeat family protein | 0.0001 | 0.0000037143 | 0.013 |
Echinococcus granulosus | kelch protein 12 | 0.0001 | 0.0003 | 0.0003 |
Echinococcus multilocularis | kelch ECH associated protein 1 | 0.0187 | 0.9972 | 0.9972 |
Schistosoma mansoni | hypothetical protein | 0.0001 | 0.0003 | 0.0003 |
Brugia malayi | BTB/POZ domain containing protein 2 | 0.0001 | 0.0000037143 | 0.013 |
Brugia malayi | hypothetical protein | 0.0001 | 0.0000037143 | 0.013 |
Loa Loa (eye worm) | hypothetical protein | 0.0001 | 0.0000037143 | 0.013 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0001 | 0 | 0.5 |
Loa Loa (eye worm) | BTB/POZ domain-containing protein 2 | 0.0001 | 0.0000037143 | 0.013 |
Trichomonas vaginalis | ankyrin repeat domain protein, putative | 0.0001 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0001 | 0.0003 | 0.0003 |
Schistosoma mansoni | hypothetical protein | 0.0187 | 1 | 1 |
Echinococcus granulosus | ectoderm neural cortex protein 1 | 0.0001 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0001 | 0.0000037143 | 0.013 |
Echinococcus multilocularis | kelch ECH associated protein 1 | 0.0187 | 0.9972 | 0.9972 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0001 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0001 | 0.0003 | 0.0003 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0001 | 0 | 0.5 |
Loa Loa (eye worm) | Btbd6 protein | 0.0001 | 0.0000037143 | 0.013 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0001 | 0 | 0.5 |
Loa Loa (eye worm) | Klhl5 protein | 0.0001 | 0.0003 | 1 |
Brugia malayi | Kelch motif family protein | 0.0001 | 0.0003 | 1 |
Echinococcus granulosus | kelch protein 10 | 0.0001 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | ring canal kelch protein | 0.0001 | 0.0003 | 1 |
Echinococcus granulosus | kelch ECH associated protein 1 like | 0.0187 | 0.9972 | 1 |
Brugia malayi | Kelch motif family protein | 0.0001 | 0.0003 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0001 | 0.0000037143 | 0.0000037143 |
Onchocerca volvulus | 0.0001 | 0.0000037143 | 1 | |
Brugia malayi | hypothetical protein | 0.0001 | 0.0000037143 | 0.013 |
Echinococcus multilocularis | kelch protein 18 | 0.0001 | 0.0003 | 0.0003 |
Onchocerca volvulus | 0.0001 | 0.0000037143 | 1 | |
Brugia malayi | Btbd7 protein | 0.0001 | 0.0000037143 | 0.013 |
Echinococcus granulosus | kelch protein 18 | 0.0001 | 0.0003 | 0.0003 |
Brugia malayi | hypothetical protein | 0.0001 | 0.0000037143 | 0.013 |
Brugia malayi | hypothetical protein | 0.0001 | 0.0000037143 | 0.013 |
Loa Loa (eye worm) | kelch domain-containing protein family protein | 0.0001 | 0.0003 | 1 |
Onchocerca volvulus | 0.0001 | 0.0000037143 | 1 | |
Brugia malayi | BTB/POZ domain containing protein | 0.0001 | 0.0000037143 | 0.013 |
Echinococcus multilocularis | kelch protein 10 | 0.0001 | 0.0003 | 0.0003 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0001 | 0 | 0.5 |
Schistosoma mansoni | btb/poz domain containing protein | 0.0001 | 0.0000037143 | 0.0000037143 |
Brugia malayi | BTB/POZ domain containing protein | 0.0001 | 0.0003 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0001 | 0.0003 | 0.0003 |
Schistosoma mansoni | hypothetical protein | 0.0001 | 0.0003 | 0.0003 |
Echinococcus granulosus | kelch ECH associated protein 1 | 0.0187 | 0.9972 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IZ (functional) | = 9 mm | Antimicrobial activity against Escherichia coli MTCC 723 assessed as diameter of growth inhibition zone at 500 ug/ml after 24 hr by cup-plate method | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.