Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | deoxyuridine 5'-triphosphate nucleotidohydrolase | 0.0155 | 0.0766 | 0.5 |
Entamoeba histolytica | thymidine kinase, putative | 0.0511 | 0.5833 | 1 |
Brugia malayi | dUTP diphosphatase | 0.0155 | 0.0766 | 0.5 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0511 | 0.5833 | 1 |
Schistosoma mansoni | deoxyuridine 5'-triphosphate nucleotidohydrolase | 0.0155 | 0.0766 | 0.5 |
Entamoeba histolytica | deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein | 0.0155 | 0.0766 | 0.1313 |
Toxoplasma gondii | deoxyuridine 5'-triphosphate nucleotidohydrolase, putative | 0.0155 | 0.0766 | 0.5 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0511 | 0.5833 | 1 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0458 | 0.5084 | 0.4676 |
Trypanosoma cruzi | thymidine kinase, putative | 0.0511 | 0.5833 | 0.5 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0511 | 0.5833 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0155 | 0.0766 | 0.1313 |
Echinococcus granulosus | neuropeptide s receptor | 0.0458 | 0.5084 | 1 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0458 | 0.5084 | 1 |
Entamoeba histolytica | deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein | 0.0155 | 0.0766 | 0.1313 |
Chlamydia trachomatis | deoxyuridine 5'-triphosphate nucleotidohydrolase | 0.0155 | 0.0766 | 0.5 |
Trypanosoma brucei | thymidine kinase | 0.0511 | 0.5833 | 0.5 |
Entamoeba histolytica | deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial precursor, putative | 0.0155 | 0.0766 | 0.1313 |
Wolbachia endosymbiont of Brugia malayi | dUTPase | 0.0155 | 0.0766 | 0.5 |
Entamoeba histolytica | deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein | 0.0155 | 0.0766 | 0.1313 |
Trypanosoma cruzi | thymidine kinase, putative | 0.0511 | 0.5833 | 0.5 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0458 | 0.5084 | 0.4676 |
Plasmodium vivax | deoxyuridine 5'-triphosphate nucleotidohydrolase, putative | 0.0155 | 0.0766 | 0.5 |
Entamoeba histolytica | deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial precursor, putative | 0.0155 | 0.0766 | 0.1313 |
Entamoeba histolytica | deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein | 0.0155 | 0.0766 | 0.1313 |
Entamoeba histolytica | hypothetical protein | 0.0155 | 0.0766 | 0.1313 |
Giardia lamblia | Thymidine kinase | 0.0511 | 0.5833 | 0.5 |
Loa Loa (eye worm) | dUTP diphosphatase | 0.0155 | 0.0766 | 0.5 |
Treponema pallidum | deoxyuridine 5'-triphosphate nucleotidohydrolase (dut) | 0.0155 | 0.0766 | 0.5 |
Leishmania major | thymidine kinase, putative | 0.0511 | 0.5833 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.