Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | brahma associated protein 60 kDa | 0.0076 | 0.0918 | 0.0918 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.0442 | 0.0442 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0027 | 0 | 0.5 |
Brugia malayi | Muscleblind-like protein | 0.0153 | 0.2334 | 0.2334 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0076 | 0.0918 | 0.0918 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0142 | 0.0142 |
Schistosoma mansoni | hypothetical protein | 0.0076 | 0.0918 | 0.0918 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.0142 | 0.0142 |
Toxoplasma gondii | SWIB/MDM2 domain-containing protein | 0.0076 | 0.0918 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.2334 | 0.2334 |
Onchocerca volvulus | 0.0076 | 0.0918 | 0.0918 | |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0648 | 0.5 |
Chlamydia trachomatis | SWIB complex protein | 0.0076 | 0.0918 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0442 | 0.0442 |
Loa Loa (eye worm) | SWIB/MDM2 domain-containing protein | 0.0076 | 0.0918 | 0.0918 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0027 | 0 | 0.5 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0062 | 0.0648 | 1 |
Echinococcus granulosus | Upstream activation factor subunit UAF30 | 0.0076 | 0.0918 | 0.0918 |
Echinococcus multilocularis | Upstream activation factor subunit UAF30 | 0.0076 | 0.0918 | 0.0918 |
Echinococcus multilocularis | protein will die slowly | 0.0564 | 1 | 1 |
Brugia malayi | brahma associated protein 60 kDa | 0.0076 | 0.0918 | 0.0918 |
Schistosoma mansoni | hypothetical protein | 0.0564 | 1 | 1 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0062 | 0.0648 | 0.0648 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0027 | 0 | 0.5 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.0648 | 0.0648 |
Schistosoma mansoni | brg-1 associated factor | 0.0076 | 0.0918 | 0.0918 |
Echinococcus multilocularis | muscleblind protein | 0.0153 | 0.2334 | 0.2334 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.0442 | 0.0442 |
Toxoplasma gondii | DNA topoisomerase domain-containing protein | 0.0076 | 0.0918 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0076 | 0.0918 | 0.5 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0027 | 0 | 0.5 |
Loa Loa (eye worm) | WD40 repeat protein | 0.0564 | 1 | 1 |
Trichomonas vaginalis | WD repeat domain, putative | 0.0564 | 1 | 1 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0153 | 0.2334 | 0.2334 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0027 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.2334 | 0.2334 |
Brugia malayi | SWIB/MDM2 domain containing protein | 0.0076 | 0.0918 | 0.0918 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0027 | 0 | 0.5 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0076 | 0.0918 | 1 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0076 | 0.0918 | 0.0918 |
Schistosoma mansoni | hypothetical protein | 0.0076 | 0.0918 | 0.0918 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0648 | 0.5 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0027 | 0 | 0.5 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0076 | 0.0918 | 1 |
Echinococcus granulosus | protein will die slowly | 0.0564 | 1 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.0648 | 0.0648 |
Trypanosoma brucei | mitochondrial RNA binding complex 1 subunit | 0.0027 | 0 | 0.5 |
Loa Loa (eye worm) | brahma associated protein | 0.0076 | 0.0918 | 0.0918 |
Chlamydia trachomatis | DNA topoisomerase I | 0.0076 | 0.0918 | 0.5 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0062 | 0.0648 | 0.7064 |
Plasmodium vivax | SWIB/MDM2 domain-containing protein, putative | 0.0076 | 0.0918 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0142 | 0.0142 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0027 | 0 | 0.5 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0648 | 0.5 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0027 | 0 | 0.5 |
Echinococcus granulosus | SWI:SNF matrix associated | 0.0076 | 0.0918 | 0.0918 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0062 | 0.0648 | 0.5 |
Echinococcus granulosus | muscleblind protein | 0.0153 | 0.2334 | 0.2334 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.0442 | 0.0442 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0076 | 0.0918 | 0.0918 |
Schistosoma mansoni | hypothetical protein | 0.0076 | 0.0918 | 0.0918 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0027 | 0 | 0.5 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0062 | 0.0648 | 0.0648 |
Trypanosoma brucei | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0027 | 0 | 0.5 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0027 | 0 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0027 | 0 | 0.5 |
Onchocerca volvulus | 0.0564 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.