Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0076 | 0.0918 | 0.0918 |
Schistosoma mansoni | hypothetical protein | 0.0076 | 0.0918 | 0.0918 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0076 | 0.0918 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0027 | 0 | 0.5 |
Brugia malayi | SWIB/MDM2 domain containing protein | 0.0076 | 0.0918 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.2334 | 0.2334 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0076 | 0.0918 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0027 | 0 | 0.5 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0648 | 0.5 |
Echinococcus granulosus | SWI:SNF matrix associated | 0.0076 | 0.0918 | 0.0918 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0062 | 0.0648 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.0442 | 0.0442 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0076 | 0.0918 | 0.0918 |
Echinococcus granulosus | muscleblind protein | 0.0153 | 0.2334 | 0.2334 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0027 | 0 | 0.5 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0062 | 0.0648 | 0.7064 |
Loa Loa (eye worm) | brahma associated protein | 0.0076 | 0.0918 | 0.0918 |
Chlamydia trachomatis | DNA topoisomerase I | 0.0076 | 0.0918 | 0.5 |
Plasmodium vivax | SWIB/MDM2 domain-containing protein, putative | 0.0076 | 0.0918 | 0.5 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0027 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0142 | 0.0142 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0648 | 0.5 |
Echinococcus granulosus | protein will die slowly | 0.0564 | 1 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.0648 | 0.0648 |
Trypanosoma brucei | mitochondrial RNA binding complex 1 subunit | 0.0027 | 0 | 0.5 |
Onchocerca volvulus | 0.0564 | 1 | 1 | |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0062 | 0.0648 | 0.0648 |
Trypanosoma brucei | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0027 | 0 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0027 | 0 | 0.5 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0027 | 0 | 0.5 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0027 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0076 | 0.0918 | 0.0918 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.0142 | 0.0142 |
Brugia malayi | Muscleblind-like protein | 0.0153 | 0.2334 | 0.2334 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0076 | 0.0918 | 0.0918 |
Schistosoma mansoni | hypothetical protein | 0.0076 | 0.0918 | 0.0918 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0142 | 0.0142 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.0442 | 0.0442 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0027 | 0 | 0.5 |
Brugia malayi | brahma associated protein 60 kDa | 0.0076 | 0.0918 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0442 | 0.0442 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0648 | 0.5 |
Chlamydia trachomatis | SWIB complex protein | 0.0076 | 0.0918 | 0.5 |
Onchocerca volvulus | 0.0076 | 0.0918 | 0.0918 | |
Toxoplasma gondii | SWIB/MDM2 domain-containing protein | 0.0076 | 0.0918 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.2334 | 0.2334 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.0648 | 0.0648 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0027 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0564 | 1 | 1 |
Brugia malayi | brahma associated protein 60 kDa | 0.0076 | 0.0918 | 0.0918 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0062 | 0.0648 | 0.0648 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0062 | 0.0648 | 1 |
Echinococcus multilocularis | Upstream activation factor subunit UAF30 | 0.0076 | 0.0918 | 0.0918 |
Echinococcus granulosus | Upstream activation factor subunit UAF30 | 0.0076 | 0.0918 | 0.0918 |
Echinococcus multilocularis | protein will die slowly | 0.0564 | 1 | 1 |
Loa Loa (eye worm) | SWIB/MDM2 domain-containing protein | 0.0076 | 0.0918 | 0.0918 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0027 | 0 | 0.5 |
Loa Loa (eye worm) | WD40 repeat protein | 0.0564 | 1 | 1 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0027 | 0 | 0.5 |
Trichomonas vaginalis | WD repeat domain, putative | 0.0564 | 1 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0027 | 0 | 0.5 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0153 | 0.2334 | 0.2334 |
Toxoplasma gondii | DNA topoisomerase domain-containing protein | 0.0076 | 0.0918 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0076 | 0.0918 | 0.5 |
Schistosoma mansoni | brg-1 associated factor | 0.0076 | 0.0918 | 0.0918 |
Echinococcus multilocularis | muscleblind protein | 0.0153 | 0.2334 | 0.2334 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.0442 | 0.0442 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.