Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0062 | 0.0648 | 0.0648 |
Trypanosoma brucei | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0027 | 0 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0027 | 0 | 0.5 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0027 | 0 | 0.5 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0027 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0076 | 0.0918 | 0.0918 |
Onchocerca volvulus | 0.0564 | 1 | 1 | |
Loa Loa (eye worm) | brahma associated protein | 0.0076 | 0.0918 | 0.0918 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0062 | 0.0648 | 0.7064 |
Chlamydia trachomatis | DNA topoisomerase I | 0.0076 | 0.0918 | 0.5 |
Plasmodium vivax | SWIB/MDM2 domain-containing protein, putative | 0.0076 | 0.0918 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0142 | 0.0142 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0027 | 0 | 0.5 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0648 | 0.5 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.0648 | 0.0648 |
Echinococcus granulosus | protein will die slowly | 0.0564 | 1 | 1 |
Trypanosoma brucei | mitochondrial RNA binding complex 1 subunit | 0.0027 | 0 | 0.5 |
Echinococcus granulosus | SWI:SNF matrix associated | 0.0076 | 0.0918 | 0.0918 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0062 | 0.0648 | 0.5 |
Echinococcus granulosus | muscleblind protein | 0.0153 | 0.2334 | 0.2334 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.0442 | 0.0442 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0076 | 0.0918 | 0.0918 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0027 | 0 | 0.5 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0027 | 0 | 0.5 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0648 | 0.5 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0076 | 0.0918 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0027 | 0 | 0.5 |
Brugia malayi | SWIB/MDM2 domain containing protein | 0.0076 | 0.0918 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.2334 | 0.2334 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0076 | 0.0918 | 0.0918 |
Schistosoma mansoni | hypothetical protein | 0.0076 | 0.0918 | 0.0918 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0076 | 0.0918 | 1 |
Toxoplasma gondii | DNA topoisomerase domain-containing protein | 0.0076 | 0.0918 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0076 | 0.0918 | 0.5 |
Echinococcus multilocularis | muscleblind protein | 0.0153 | 0.2334 | 0.2334 |
Schistosoma mansoni | brg-1 associated factor | 0.0076 | 0.0918 | 0.0918 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.0442 | 0.0442 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0027 | 0 | 0.5 |
Loa Loa (eye worm) | WD40 repeat protein | 0.0564 | 1 | 1 |
Trichomonas vaginalis | WD repeat domain, putative | 0.0564 | 1 | 1 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0153 | 0.2334 | 0.2334 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0027 | 0 | 0.5 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0062 | 0.0648 | 1 |
Echinococcus granulosus | Upstream activation factor subunit UAF30 | 0.0076 | 0.0918 | 0.0918 |
Echinococcus multilocularis | Upstream activation factor subunit UAF30 | 0.0076 | 0.0918 | 0.0918 |
Echinococcus multilocularis | protein will die slowly | 0.0564 | 1 | 1 |
Loa Loa (eye worm) | SWIB/MDM2 domain-containing protein | 0.0076 | 0.0918 | 0.0918 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0027 | 0 | 0.5 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.0648 | 0.0648 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0027 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0564 | 1 | 1 |
Brugia malayi | brahma associated protein 60 kDa | 0.0076 | 0.0918 | 0.0918 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0062 | 0.0648 | 0.0648 |
Onchocerca volvulus | 0.0076 | 0.0918 | 0.0918 | |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.2334 | 0.2334 |
Toxoplasma gondii | SWIB/MDM2 domain-containing protein | 0.0076 | 0.0918 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0442 | 0.0442 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0648 | 0.5 |
Chlamydia trachomatis | SWIB complex protein | 0.0076 | 0.0918 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.0442 | 0.0442 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0027 | 0 | 0.5 |
Brugia malayi | brahma associated protein 60 kDa | 0.0076 | 0.0918 | 0.0918 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.0142 | 0.0142 |
Brugia malayi | Muscleblind-like protein | 0.0153 | 0.2334 | 0.2334 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0076 | 0.0918 | 0.0918 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0142 | 0.0142 |
Schistosoma mansoni | hypothetical protein | 0.0076 | 0.0918 | 0.0918 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.