Detailed information for compound 1805210

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 325.319 | Formula: C17H15N3O4
  • H donors: 0 H acceptors: 4 LogP: 2.45 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: [O-][N+](=O)c1ccc2c(c1)nc(n2C)COc1ccc(cc1)C(=O)C
  • InChi: 1S/C17H15N3O4/c1-11(21)12-3-6-14(7-4-12)24-10-17-18-15-9-13(20(22)23)5-8-16(15)19(17)2/h3-9H,10H2,1-2H3
  • InChiKey: SJNXPLIVUMZQEU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.0037 0.0057 0.1102
Brugia malayi hypothetical protein 0.0037 0.0057 0.0875
Brugia malayi RE15519p 0.0037 0.0057 0.0875
Echinococcus granulosus allatostatin A receptor 0.0037 0.0057 0.0057
Echinococcus multilocularis orexin receptor type 2 0.0037 0.0057 0.0057
Schistosoma mansoni biogenic amine receptor 0.0037 0.0057 0.1102
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0037 0.0057 0.1102
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Brugia malayi Dopamine receptor protein 1 0.0037 0.0057 0.0875
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0102 0.1965
Schistosoma mansoni neuropeptide f receptor 76f 0.0037 0.0057 0.1102
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0254 0.0254
Brugia malayi hypothetical protein 0.0037 0.0057 0.0875
Onchocerca volvulus 0.0037 0.0057 0.0759
Brugia malayi Pre-SET motif family protein 0.0208 0.0653 1
Echinococcus granulosus 7tm_1 domain containing protein 0.0037 0.0057 0.0057
Echinococcus multilocularis fmrfamide receptor 0.0037 0.0057 0.0057
Plasmodium falciparum heat shock protein 70 0.002 0 0.5
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0093 0.0254 0.3888
Echinococcus granulosus somatostatin receptor 0.0037 0.0057 0.0057
Onchocerca volvulus Neuropeptide F receptor homolog 0.0037 0.0057 0.0759
Echinococcus granulosus fmrfamide receptor 0.0037 0.0057 0.0057
Echinococcus granulosus G protein coupled receptor 139 0.0037 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0057 0.1102
Schistosoma mansoni biogenic amine receptor 0.0037 0.0057 0.1102
Echinococcus granulosus neuropeptide receptor A26 0.0037 0.0057 0.0057
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0037 0.0057 0.0057
Schistosoma mansoni opsin-like receptor 0.0037 0.0057 0.1102
Schistosoma mansoni amine GPCR 0.0037 0.0057 0.1102
Brugia malayi Dopamine receptor protein 2 0.0037 0.0057 0.0875
Brugia malayi hypothetical protein 0.0036 0.0055 0.0844
Onchocerca volvulus 0.0037 0.0057 0.0759
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0037 0.0057 0.0759
Echinococcus multilocularis g protein coupled receptor 0.0037 0.0057 0.0057
Brugia malayi G-protein coupled receptor 0.0037 0.0057 0.0875
Schistosoma mansoni growth hormone secretagogue receptor 0.0037 0.0057 0.1102
Leishmania major glucose-regulated protein 78, putative 0.002 0 0.5
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0055 0.1063
Schistosoma mansoni biogenic amine (5HT) receptor 0.0037 0.0057 0.1102
Onchocerca volvulus 0.0037 0.0057 0.0759
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0037 0.0057 0.0057
Brugia malayi neuropeptide F receptor 0.0037 0.0057 0.0875
Brugia malayi hypothetical protein 0.0037 0.0057 0.0875
Echinococcus granulosus biogenic amine 5HT receptor 0.0037 0.0057 0.0057
Echinococcus granulosus g protein coupled receptor 0.0037 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0037 0.0057 0.0057
Onchocerca volvulus 0.0037 0.0057 0.0759
Brugia malayi Melatonin receptor type 1A 0.0037 0.0057 0.0875
Plasmodium vivax SET domain protein, putative 0.003 0.0034 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Trypanosoma brucei heat shock protein 70 (hsp70), putative 0.002 0 0.5
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0034 0.0653
Onchocerca volvulus 0.0037 0.0057 0.0759
Loa Loa (eye worm) melatonin receptor type 1A 0.0037 0.0057 0.0875
Onchocerca volvulus 0.0037 0.0057 0.0759
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0037 0.0057 0.1102
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0037 0.0057 0.1102
Brugia malayi neuropeptide F receptor 0.0037 0.0057 0.0875
Leishmania major heat-shock protein hsp70, putative 0.002 0 0.5
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0254 0.0254
Echinococcus granulosus neuropeptide Y receptor 0.0037 0.0057 0.0057
Echinococcus multilocularis solute carrier family 28 0.2897 1 1
Echinococcus multilocularis neuropeptide Y receptor 0.0037 0.0057 0.0057
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0037 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0254 0.4895
Echinococcus granulosus tm gpcr rhodopsin 0.0037 0.0057 0.0057
Schistosoma mansoni adenoreceptor 0.0037 0.0057 0.1102
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0037 0.0057 0.0875
Plasmodium falciparum heat shock protein 70 0.002 0 0.5
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0057 0.0057
Echinococcus multilocularis neuropeptide receptor 0.0037 0.0057 0.0057
Entamoeba histolytica hypothetical protein 0.0036 0.0055 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0055 0.0055
Schistosoma mansoni neuropeptide receptor 0.0037 0.0057 0.1102
Echinococcus multilocularis serotonin receptor 0.0037 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Brugia malayi hypothetical protein 0.0037 0.0057 0.0875
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0037 0.0057 0.0875
Brugia malayi hypothetical protein 0.0037 0.0057 0.0875
Brugia malayi GnHR receptor homolog 0.0037 0.0057 0.0875
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0057 0.0057
Echinococcus multilocularis neuropeptide s receptor 0.0037 0.0057 0.0057
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0057 0.0057
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0057 0.0057
Schistosoma mansoni biogenic amine (5HT) receptor 0.0037 0.0057 0.1102
Echinococcus multilocularis g-protein coupled receptor 0.0037 0.0057 0.0057
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0057 0.1102
Echinococcus multilocularis fmrfamide receptor 0.0037 0.0057 0.0057
Schistosoma mansoni alpha-1 adrenergic receptor 0.0037 0.0057 0.1102
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Brugia malayi Dopamine receptor 0.0037 0.0057 0.0875
Onchocerca volvulus 0.0037 0.0057 0.0759
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Echinococcus granulosus serotonin receptor 0.0037 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Brugia malayi Serotonin receptor 0.0037 0.0057 0.0875
Echinococcus granulosus neuropeptides capa receptor 0.0037 0.0057 0.0057
Schistosoma mansoni amine GPCR 0.0037 0.0057 0.1102
Onchocerca volvulus 0.0037 0.0057 0.0759
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0057 0.1102
Giardia lamblia Cytosolic HSP70 0.002 0 0.5
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0037 0.0057 0.0875
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Onchocerca volvulus 0.0037 0.0057 0.0759
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Echinococcus granulosus tm gpcr rhodopsin 0.0037 0.0057 0.0057
Brugia malayi Serotonin receptor 0.0037 0.0057 0.0875
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Echinococcus granulosus alpha 1A adrenergic receptor 0.0037 0.0057 0.0057
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0037 0.0057 0.1102
Brugia malayi AKH receptor 0.0037 0.0057 0.0875
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0037 0.0057 0.1102
Schistosoma mansoni hypothetical protein 0.0169 0.0518 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0102 0.1561
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0034 0.0034
Echinococcus granulosus geminin 0.0169 0.0518 0.0518
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0037 0.0057 0.0057
Trypanosoma brucei heat shock 70 kDa protein, putative 0.002 0 0.5
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Onchocerca volvulus 0.0037 0.0057 0.0759
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0037 0.0057 0.1102
Schistosoma mansoni amine GPCR 0.0037 0.0057 0.1102
Brugia malayi hypothetical protein 0.0037 0.0057 0.0875
Entamoeba histolytica hypothetical protein 0.0036 0.0055 1
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0037 0.0057 0.0875
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0034 0.0034
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0057 0.0057
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0034 0.0653
Onchocerca volvulus 0.0037 0.0057 0.0759
Schistosoma mansoni myosin xvIII 0.0037 0.0057 0.1102
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0034 0.0034
Schistosoma mansoni neuropeptide receptor 0.0037 0.0057 0.1102
Echinococcus multilocularis G protein coupled receptor 139 0.0037 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Onchocerca volvulus 0.0037 0.0057 0.0759
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0037 0.0057 0.0057
Schistosoma mansoni hypothetical protein 0.0037 0.0057 0.1102
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0208 0.0653 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0057 0.0057
Echinococcus multilocularis neuropeptides capa receptor 0.0037 0.0057 0.0057
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0037 0.0057 0.0057
Onchocerca volvulus 0.0037 0.0057 0.0759
Schistosoma mansoni biogenic amine receptor 0.0037 0.0057 0.1102
Schistosoma mansoni neuropeptide F-like receptor 0.0037 0.0057 0.1102
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0057 0.1102
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.003 0.003
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0037 0.0057 0.1102
Echinococcus multilocularis geminin 0.0169 0.0518 0.0518
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0037 0.0057 0.0057
Onchocerca volvulus 0.0037 0.0057 0.0759
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0037 0.0057 0.1102
Echinococcus multilocularis G-protein coupled receptor, putative 0.0037 0.0057 0.0057
Onchocerca volvulus 0.0037 0.0057 0.0759
Schistosoma mansoni amine GPCR 0.0037 0.0057 0.1102
Brugia malayi Tachykinin-like peptides receptor 99D 0.0037 0.0057 0.0875
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0034 0.0653
Trypanosoma cruzi heat shock protein 70 (hsp70), putative 0.002 0 0.5
Onchocerca volvulus 0.003 0.0034 0.045
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0057 0.1102
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0057 0.1102
Entamoeba histolytica hypothetical protein 0.0036 0.0055 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0037 0.0057 0.0057
Echinococcus granulosus neuropeptide s receptor 0.0037 0.0057 0.0057
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0037 0.0057 0.1102
Brugia malayi hypothetical protein 0.0037 0.0057 0.0875
Brugia malayi putative neuropeptide receptor 0.0037 0.0057 0.0875
Echinococcus granulosus g-protein coupled receptor 0.0037 0.0057 0.0057
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0057 0.1102
Plasmodium falciparum heat shock protein 70 0.002 0 0.5
Echinococcus granulosus neuropeptide receptor 0.0037 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Schistosoma mansoni hypothetical protein 0.0037 0.0057 0.1102
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Echinococcus multilocularis neuropeptide receptor A26 0.0037 0.0057 0.0057
Echinococcus multilocularis somatostatin receptor 0.0037 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0254 0.4895
Echinococcus granulosus Na+ dependent nucleoside transporter 0.2897 1 1
Loa Loa (eye worm) neuropeptide F receptor 0.0037 0.0057 0.0875
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0037 0.0057 0.0875
Echinococcus granulosus neuropeptide receptor 0.0037 0.0057 0.0057
Echinococcus multilocularis dro:myosuppressin receptor 0.0037 0.0057 0.0057
Echinococcus multilocularis sodium:nucleoside cotransporter 2 0.189 0.6498 0.6498
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Echinococcus granulosus tm gpcr rhodopsin 0.0037 0.0057 0.0057
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0254 0.0254
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0037 0.0057 0.1102
Loa Loa (eye worm) neuropeptide F receptor 0.0037 0.0057 0.0875
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0034 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0034 0.0653
Echinococcus granulosus biogenic amine 5HT receptor 0.0037 0.0057 0.0057
Echinococcus multilocularis neuropeptides capa receptor 0.0037 0.0057 0.0057
Trichomonas vaginalis set domain proteins, putative 0.0237 0.0753 1
Echinococcus granulosus peptide allatostatin:somatostatin 0.0037 0.0057 0.0057
Brugia malayi ORL1-like opioid receptor 0.0037 0.0057 0.0875
Giardia lamblia Bip 0.002 0 0.5
Schistosoma mansoni histamine h1 receptor 0.0037 0.0057 0.1102
Echinococcus granulosus concentrative Na nucleoside cotransporter 0.2897 1 1
Echinococcus granulosus tachykinin peptides receptor 99D 0.0037 0.0057 0.0057
Onchocerca volvulus 0.0237 0.0753 1
Echinococcus multilocularis concentrative Na+ nucleoside cotransporter 0.2897 1 1
Echinococcus granulosus neuropeptide Y receptor 0.0037 0.0057 0.0057
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0057 0.1102
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Schistosoma mansoni opsin-like receptor 0.0037 0.0057 0.1102
Echinococcus multilocularis serotonin receptor 0.0037 0.0057 0.0057
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0055 0.0055
Echinococcus granulosus dro:myosuppressin receptor 0.0037 0.0057 0.0057
Brugia malayi hypothetical protein 0.0037 0.0057 0.0875
Echinococcus multilocularis sex peptide receptor 0.0037 0.0057 0.0057
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0037 0.0057 0.1102
Brugia malayi putative neuropeptide receptor NPR1 0.0037 0.0057 0.0875
Loa Loa (eye worm) G-protein coupled receptor 0.0037 0.0057 0.0875
Trypanosoma cruzi glucose-regulated protein 78, putative 0.002 0 0.5
Brugia malayi hypothetical protein 0.0037 0.0057 0.0875
Loa Loa (eye worm) hypothetical protein 0.003 0.0034 0.0518
Echinococcus granulosus g protein coupled receptor 0.0037 0.0057 0.0057
Loa Loa (eye worm) TYRA-2 protein 0.0037 0.0057 0.0875
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0037 0.0057 0.0057
Brugia malayi G protein-coupled receptor 0.0037 0.0057 0.0875
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0254 0.0254
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0057 0.0057
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0057 0.0057
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0093 0.0254 0.3888
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0057 0.0057
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0037 0.0057 0.0057
Schistosoma mansoni opsin-like receptor 0.0037 0.0057 0.1102
Echinococcus granulosus neuropeptide FF receptor 2 0.0037 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Echinococcus granulosus hypothetical protein 0.0037 0.0057 0.0057
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0037 0.0057 0.0057
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Echinococcus multilocularis g protein coupled receptor 0.0037 0.0057 0.0057
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Entamoeba histolytica hypothetical protein 0.0036 0.0055 1
Echinococcus multilocularis tumor protein p63 0.0338 0.1103 0.1103
Echinococcus granulosus g protein coupled receptor 0.0037 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Echinococcus granulosus sex peptide receptor 0.0037 0.0057 0.0057
Leishmania major heat-shock protein hsp70, putative 0.002 0 0.5
Echinococcus granulosus neuropeptides capa receptor 0.0037 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Onchocerca volvulus 0.0037 0.0057 0.0759
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.0057 0.1102
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0037 0.0057 0.0875
Brugia malayi larval opioid receptor 0.0037 0.0057 0.0875
Schistosoma mansoni neuropeptide receptor 0.0037 0.0057 0.1102
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Brugia malayi hypothetical protein 0.0037 0.0057 0.0875
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0254 0.4895
Echinococcus granulosus tumor protein p63 0.0338 0.1103 0.1103
Brugia malayi G protein-coupled receptor F59B2.13 0.0037 0.0057 0.0875
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0037 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Trypanosoma brucei heat shock protein 70 0.002 0 0.5
Echinococcus multilocularis g protein coupled receptor 0.0037 0.0057 0.0057
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0057 0.0057
Schistosoma mansoni hypothetical protein 0.0036 0.0055 0.1063
Schistosoma mansoni amine GPCR 0.0037 0.0057 0.1102
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0037 0.0057 0.0057
Schistosoma mansoni neuropeptide F-like receptor 0.0037 0.0057 0.1102
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0037 0.0057 0.0875
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0037 0.0057 0.0875
Echinococcus multilocularis allatostatin A receptor 0.0037 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Echinococcus multilocularis neuropeptide FF receptor 2 0.0037 0.0057 0.0057
Schistosoma mansoni hypothetical protein 0.0037 0.0057 0.1102
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0037 0.0057 0.1102
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0037 0.0057 0.0875
Schistosoma mansoni hypothetical protein 0.0169 0.0518 1
Trypanosoma cruzi heat shock protein 70 (hsp70), putative 0.002 0 0.5
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Trypanosoma brucei luminal binding protein 1 (BiP), putative 0.002 0 0.5
Echinococcus multilocularis neuropeptide Y receptor 0.0037 0.0057 0.0057
Echinococcus granulosus orexin receptor type 2 0.0037 0.0057 0.0057
Loa Loa (eye worm) G-protein coupled receptor 0.0037 0.0057 0.0875
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0037 0.0057 0.0057
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0037 0.0057 0.0875
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Trypanosoma brucei luminal binding protein 1 (BiP), putative 0.002 0 0.5
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0037 0.0057 0.1102
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0037 0.0057 0.0057
Schistosoma mansoni neuropeptide receptor 0.0037 0.0057 0.1102
Leishmania major heat shock protein 70-related protein 0.002 0 0.5
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0037 0.0057 0.0057
Brugia malayi G-protein coupled receptor 0.0037 0.0057 0.0875
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Brugia malayi sulfakinin receptor protein 0.0037 0.0057 0.0875
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875
Onchocerca volvulus 0.0049 0.0102 0.1354
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0037 0.0057 0.0057
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0037 0.0057 0.0057
Echinococcus multilocularis neuropeptide receptor 0.0037 0.0057 0.0057
Brugia malayi Pre-SET motif family protein 0.003 0.0034 0.0518
Onchocerca volvulus 0.0037 0.0057 0.0759
Brugia malayi follicle stimulating hormone receptor 0.0037 0.0057 0.0875
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0037 0.0057 0.0057
Echinococcus granulosus 7TM GPCR rhodopsin 0.0037 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0037 0.0057 0.0875

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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