Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0705 | 0.0705 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0144 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0705 | 0.0705 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0144 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.2766 | 0.8959 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0144 | 0.5 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0027 | 0.1345 | 0.1185 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0144 | 0.5 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.1587 | 0.1587 |
Onchocerca volvulus | 0.0056 | 0.3055 | 1 | |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0056 | 0.3042 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1812 | 0.5508 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.1345 | 0.3821 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2994 | 0.9781 |
Echinococcus granulosus | lamin dm0 | 0.0056 | 0.3055 | 0.2926 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0288 | 0.0108 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0705 | 0.1506 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0705 | 0.1527 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0144 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.3055 | 1 |
Echinococcus multilocularis | lamin | 0.0056 | 0.3055 | 0.2926 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2766 | 0.8956 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0027 | 0.1345 | 0.1185 |
Echinococcus multilocularis | geminin | 0.0174 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0705 | 0.1506 |
Echinococcus granulosus | lamin | 0.0056 | 0.3055 | 0.2926 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0062 | 0.3435 | 0.3435 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.1488 | 0.435 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.1587 | 0.1587 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.2766 | 0.8956 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0144 | 0.5 |
Echinococcus granulosus | intermediate filament protein | 0.0056 | 0.3055 | 0.2926 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0056 | 0.3055 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0144 | 0.5 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0705 | 0.0532 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0705 | 0.0705 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0144 | 0.5 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0288 | 0.0108 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.1285 | 0.3602 |
Brugia malayi | intermediate filament protein | 0.0056 | 0.3055 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0144 | 0.5 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.003 | 0.1521 | 0.4469 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0182 | 0.0182 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0705 | 0.0532 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0144 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0144 | 0.5 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0144 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.1285 | 0.3602 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0705 | 0.0532 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.1587 | 0.1431 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0144 | 0.5 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0705 | 0.1527 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0144 | 0.5 |
Schistosoma mansoni | lamin | 0.0056 | 0.3055 | 0.3055 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.1812 | 0.5519 |
Echinococcus multilocularis | musashi | 0.0056 | 0.3055 | 0.2926 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0705 | 0.0532 |
Onchocerca volvulus | 0.0056 | 0.3055 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0174 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.1812 | 0.1812 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0056 | 0.3055 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.1488 | 0.1488 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0144 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0174 | 1 | 1 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.003 | 0.1521 | 0.4455 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.2766 | 0.8959 |
Echinococcus multilocularis | lamin dm0 | 0.0056 | 0.3055 | 0.2926 |
Schistosoma mansoni | intermediate filament proteins | 0.0056 | 0.3055 | 0.3055 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.1587 | 0.1431 |
Loa Loa (eye worm) | intermediate filament protein | 0.0056 | 0.3055 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0705 | 0.0532 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.1488 | 0.4336 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0144 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0705 | 0.0705 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0144 | 0.5 |
Schistosoma mansoni | lamin | 0.0056 | 0.3055 | 0.3055 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0705 | 0.0532 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.0144 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.