Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.011 | 0.3564 | 1 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0092 | 0.269 | 0.6061 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.3564 | 0.3564 |
Brugia malayi | Blistered cuticle protein 3 | 0.0074 | 0.1761 | 0.0479 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.011 | 0.3564 | 0.2563 |
Trypanosoma cruzi | endonuclease G, putative | 0.0066 | 0.1346 | 0.5 |
Leishmania major | DNA/RNA non-specific endonuclease-like protein | 0.0066 | 0.1346 | 0.5 |
Trypanosoma brucei | endonuclease G, putative | 0.0066 | 0.1346 | 0.5 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.011 | 0.3564 | 1 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.011 | 0.3564 | 1 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0092 | 0.269 | 0.6061 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.011 | 0.3564 | 1 |
Toxoplasma gondii | DNA/RNA non-specific endonuclease | 0.0066 | 0.1346 | 0.5 |
Echinococcus multilocularis | ectonucleotide | 0.0092 | 0.269 | 0.6061 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.011 | 0.3564 | 1 |
Onchocerca volvulus | 0.011 | 0.3564 | 0.2189 | |
Trypanosoma brucei | endonuclease G, putative | 0.0066 | 0.1346 | 0.5 |
Echinococcus granulosus | ectonucleotide | 0.0092 | 0.269 | 0.6061 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.011 | 0.3564 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.3564 | 0.3564 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.011 | 0.3564 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.3564 | 0.3564 |
Schistosoma mansoni | hypothetical protein | 0.0236 | 1 | 1 |
Onchocerca volvulus | 0.011 | 0.3564 | 0.2189 | |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.011 | 0.3564 | 1 |
Loa Loa (eye worm) | thrombospondin type 1 domain-containing protein | 0.0236 | 1 | 1 |
Trypanosoma cruzi | endonuclease G, putative | 0.0066 | 0.1346 | 0.5 |
Brugia malayi | Type I phosphodiesterase / nucleotide pyrophosphatase family protein | 0.011 | 0.3564 | 0.2563 |
Leishmania major | endonuclease G, putative | 0.0066 | 0.1346 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.269 | 0.269 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.011 | 0.3564 | 0.2563 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.011 | 0.3564 | 1 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0074 | 0.1761 | 0.1761 |
Onchocerca volvulus | 0.0236 | 1 | 1 | |
Trypanosoma brucei | endonuclease G, putative | 0.0066 | 0.1346 | 0.5 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.011 | 0.3564 | 1 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.011 | 0.3564 | 0.2563 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.011 | 0.3564 | 0.2563 |
Trypanosoma cruzi | DNA/RNA non-specific endonuclease protein-like, putative | 0.0066 | 0.1346 | 0.5 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.011 | 0.3564 | 1 |
Trypanosoma cruzi | DNA/RNA non-specific endonuclease protein-like, putative | 0.0066 | 0.1346 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.