Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | phosphatidylinositol-glycan biosynthesis class O protein, putative | 0.0083 | 0 | 0.5 |
Trypanosoma brucei | endonuclease G, putative | 0.0317 | 0.2216 | 1 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0528 | 0.4211 | 1 |
Echinococcus granulosus | Endonuclease G | 0.0317 | 0.2216 | 0.5262 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0144 | 0.0572 | 0.0572 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0445 | 0.3425 | 0.8134 |
Trypanosoma cruzi | endonuclease G, putative | 0.0317 | 0.2216 | 0.5 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0528 | 0.4211 | 0.4211 |
Loa Loa (eye worm) | hypothetical protein | 0.0528 | 0.4211 | 0.4211 |
Loa Loa (eye worm) | thrombospondin type 1 domain-containing protein | 0.1141 | 1 | 1 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0528 | 0.4211 | 1 |
Onchocerca volvulus | 0.0528 | 0.4211 | 0.4211 | |
Loa Loa (eye worm) | hypothetical protein | 0.0144 | 0.0572 | 0.0572 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0528 | 0.4211 | 1 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0528 | 0.4211 | 1 |
Onchocerca volvulus | 0.1141 | 1 | 1 | |
Trypanosoma cruzi | DNA/RNA non-specific endonuclease protein-like, putative | 0.0317 | 0.2216 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.1141 | 1 | 1 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0528 | 0.4211 | 1 |
Brugia malayi | Type I phosphodiesterase / nucleotide pyrophosphatase family protein | 0.0528 | 0.4211 | 0.4211 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0528 | 0.4211 | 0.4211 |
Echinococcus multilocularis | serotonin receptor | 0.0144 | 0.0572 | 0.1358 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0528 | 0.4211 | 1 |
Schistosoma mansoni | endonuclease related | 0.0317 | 0.2216 | 0.2216 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0528 | 0.4211 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0445 | 0.3425 | 0.3425 |
Trypanosoma cruzi | DNA/RNA non-specific endonuclease protein-like, putative | 0.0317 | 0.2216 | 0.5 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0144 | 0.0572 | 0.1358 |
Toxoplasma gondii | DNA/RNA non-specific endonuclease | 0.0317 | 0.2216 | 0.5 |
Plasmodium falciparum | GPI ethanolamine phosphate transferase 3, putative | 0.0083 | 0 | 0.5 |
Echinococcus granulosus | ectonucleotide | 0.0445 | 0.3425 | 0.8134 |
Trypanosoma brucei | endonuclease G, putative | 0.0317 | 0.2216 | 1 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0528 | 0.4211 | 1 |
Trypanosoma brucei | endonuclease G, putative | 0.0317 | 0.2216 | 1 |
Leishmania major | endonuclease G, putative | 0.0317 | 0.2216 | 1 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0528 | 0.4211 | 1 |
Entamoeba histolytica | phosphatidylinositol-glycan biosynthesis class O protein, putative | 0.0083 | 0 | 0.5 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0445 | 0.3425 | 0.8134 |
Leishmania major | DNA/RNA non-specific endonuclease-like protein | 0.0317 | 0.2216 | 1 |
Echinococcus multilocularis | Endonuclease G | 0.0317 | 0.2216 | 0.5262 |
Loa Loa (eye worm) | hypothetical protein | 0.0528 | 0.4211 | 0.4211 |
Loa Loa (eye worm) | hypothetical protein | 0.0144 | 0.0572 | 0.0572 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0528 | 0.4211 | 0.4211 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0528 | 0.4211 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0083 | 0 | 0.5 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0528 | 0.4211 | 0.4211 |
Echinococcus multilocularis | serotonin receptor | 0.0144 | 0.0572 | 0.1358 |
Echinococcus multilocularis | ectonucleotide | 0.0445 | 0.3425 | 0.8134 |
Loa Loa (eye worm) | hypothetical protein | 0.0528 | 0.4211 | 0.4211 |
Brugia malayi | endonuclease G, mitochondrial precursor | 0.0317 | 0.2216 | 0.2216 |
Mycobacterium leprae | hypothetical protein | 0.0083 | 0 | 0.5 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0528 | 0.4211 | 1 |
Giardia lamblia | Phosphatidylinositol-glycan biosynthesis, class O protein | 0.0083 | 0 | 0.5 |
Trypanosoma cruzi | endonuclease G, putative | 0.0317 | 0.2216 | 0.5 |
Onchocerca volvulus | 0.0528 | 0.4211 | 0.4211 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.