TDR Targets

Basic information

Technical information

TDR Targets ID: 183312
Name: 1-[2,6-di(propan-2-yl)phenyl]-3-[(1-naphthale n-2-ylcyclopentyl)methyl]urea
MW: 428.609 | Formula: C29H36N2O
H donors: 2 H acceptors: 1 LogP: 7.76 Rotable bonds: 8
Rule of 5 violations (Lipinski): 1
SMILES: O=C(Nc1c(cccc1C(C)C)C(C)C)NCC1(CCCC1)c1ccc2c(c1)cccc2
InChi: 1S/C29H36N2O/c1-20(2)25-12-9-13-26(21(3)4)27(25)31-28(32)30-19-29(16-7-8-17-29)24-15-14-22-10-5-6-11-23(22)18-24/h5-6,9-15,18,20-21H,7-8,16-17,19H2,1-4H3,(H2,30,31,32)
InChiKey: VJYPLIUNFFEKMJ-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

1-(2,6-diisopropylphenyl)-3-[[1-(2-naphthyl)cyclopentyl]methyl]urea
1-(2,6-diisopropylphenyl)-3-[[1-(2-naphthalenyl)cyclopentyl]methyl]urea
3-[2,6-di(propan-2-yl)phenyl]-1-[(1-naphthalen-2-ylcyclopentyl)methyl]urea
3-(2,6-diisopropylphenyl)-1-[[1-(2-naphthyl)cyclopentyl]methyl]urea

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Oryctolagus cuniculus	Acyl-CoA:cholesterol acyltransferase	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_133487	All targets in OG5_133487
Echinococcus granulosus	sterol O acyltransferase 1	Get druggable targets OG5_133487	All targets in OG5_133487
Schistosoma japonicum	ko:K00637 sterol O-acyltransferase [EC2.3.1.26], putative	Get druggable targets OG5_133487	All targets in OG5_133487
Echinococcus multilocularis	sterol O acyltransferase 1	Get druggable targets OG5_133487	All targets in OG5_133487
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_133487	All targets in OG5_133487
Schistosoma mansoni	sterol O-acyltransferase 1	Get druggable targets OG5_133487	All targets in OG5_133487

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Neospora caninum	sterol O-acyltransferase, putative	Acyl-CoA:cholesterol acyltransferase	305 aa	258 aa	20.2 %
Dictyostelium discoideum	diacylglycerol O-acyltransferase 1	Acyl-CoA:cholesterol acyltransferase	305 aa	278 aa	21.9 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	NCK adaptor protein	0.0414	0.3459	0.3459
Schistosoma mansoni	protein tyrosine kinase	0.0284	0.0453	0.0453
Plasmodium falciparum	protein kinase, putative	0.0284	0.0453	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0284	0.0453	0.5
Echinococcus granulosus	protein tyrosine kinase	0.0284	0.0453	0.0453
Schistosoma mansoni	tyrosine kinase	0.0284	0.0453	0.0453
Loa Loa (eye worm)	TK protein kinase	0.0284	0.0453	0.0453
Brugia malayi	Protein kinase domain containing protein	0.0697	1	1
Schistosoma mansoni	ephrin receptor	0.0284	0.0453	0.0453
Loa Loa (eye worm)	hypothetical protein	0.0414	0.3459	0.3459
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0284	0.0453	0.0453
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0414	0.3459	0.3459
Schistosoma mansoni	SH2A	0.0414	0.3459	0.3459
Loa Loa (eye worm)	TKL/STKR/TYPE1 protein kinase	0.0284	0.0453	0.0453
Toxoplasma gondii	protein kinase	0.0284	0.0453	0.5
Loa Loa (eye worm)	TK protein kinase	0.0284	0.0453	0.0453
Trichomonas vaginalis	protein tyrosine kinase, putative	0.0284	0.0453	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Echinococcus multilocularis	tyrosine protein kinase	0.0284	0.0453	0.0453
Brugia malayi	RhoGAP domain containing protein	0.0414	0.3459	0.3148
Brugia malayi	SH2 domain containing protein	0.0697	1	1
Echinococcus granulosus	phosphatidylinositol 3 kinase regulatory subunit	0.0414	0.3459	0.3459
Echinococcus granulosus	expressed conserved protein	0.0414	0.3459	0.3459
Echinococcus granulosus	SH2 domain containing adapter protein F	0.0414	0.3459	0.3459
Echinococcus multilocularis	tensin	0.0414	0.3459	0.3459
Schistosoma mansoni	tyrosine kinase	0.0284	0.0453	0.0453
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Trichomonas vaginalis	serine/threonine-protein kinase wnk, putative	0.0284	0.0453	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Echinococcus multilocularis	tyrosine kinase	0.0284	0.0453	0.0453
Echinococcus granulosus	raf serine:threonine protein kinase	0.0284	0.0453	0.0453
Loa Loa (eye worm)	TK/FER protein kinase	0.0697	1	1
Echinococcus multilocularis	macrophage colony stimulating factor 1 receptor	0.0284	0.0453	0.0453
Schistosoma mansoni	chimerin-related rho-gtpase-activating protein	0.0414	0.3459	0.3459
Schistosoma mansoni	growth factor receptor-bound protein	0.0414	0.3459	0.3459
Echinococcus multilocularis	tyrosine protein kinase Fps85D	0.0697	1	1
Loa Loa (eye worm)	TK protein kinase	0.0284	0.0453	0.0453
Onchocerca volvulus		0.0414	0.3459	0.3148
Toxoplasma gondii	STE kinase	0.0284	0.0453	0.5
Onchocerca volvulus		0.0697	1	1
Brugia malayi	Variant SH3 domain containing protein	0.0414	0.3459	0.3148
Loa Loa (eye worm)	hypothetical protein	0.0284	0.0453	0.0453
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Brugia malayi	SRC-1	0.0697	1	1
Echinococcus multilocularis	raf serine:threonine protein kinase	0.0284	0.0453	0.0453
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0284	0.0453	0.0453
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Loa Loa (eye worm)	hypothetical protein	0.0414	0.3459	0.3459
Echinococcus multilocularis	protein kinase	0.0284	0.0453	0.0453
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.0697	1	1
Leishmania major	protein kinase, putative	0.0284	0.0453	0.5
Echinococcus granulosus	tyrosine protein kinase Fps85D	0.0697	1	1
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0414	0.3459	0.3459
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0414	0.3459	0.3148
Schistosoma mansoni	tyrosine kinase	0.0284	0.0453	0.0453
Onchocerca volvulus	Suppressor of cytokine signaling at 36E homolog	0.0414	0.3459	0.3148
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Echinococcus multilocularis	suppressor of cytokine signaling 7	0.0414	0.3459	0.3459
Loa Loa (eye worm)	SH2 domain-containing protein	0.0414	0.3459	0.3459
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0284	0.0453	0.0453
Schistosoma mansoni	tyrosine kinase	0.0284	0.0453	0.0453
Echinococcus granulosus	epidermal growth factor receptor	0.0284	0.0453	0.0453
Schistosoma mansoni	ephrin receptor	0.0284	0.0453	0.0453
Echinococcus multilocularis	phosphatidylinositol 3 kinase regulatory subunit	0.0414	0.3459	0.3459
Brugia malayi	Protein kinase domain containing protein	0.0697	1	1
Schistosoma mansoni	tensin-related	0.0414	0.3459	0.3459
Trypanosoma brucei	AGC/RSK family serine/threonine kinase, putative	0.0284	0.0453	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0284	0.0453	0.0453
Schistosoma mansoni	protein kinase	0.0284	0.0453	0.0453
Plasmodium vivax	protein kinase, putative	0.0284	0.0453	0.5
Echinococcus granulosus	kinase suppressor of Ras 1	0.0284	0.0453	0.0453
Echinococcus granulosus	tyrosine protein kinase csk	0.0284	0.0453	0.0453
Schistosoma mansoni	serine/threonine protein kinase	0.0284	0.0453	0.0453
Echinococcus granulosus	integrin linked protein kinase	0.0284	0.0453	0.0453
Brugia malayi	tRNA modification GTPase TrmE family protein	0.0414	0.3459	0.3148
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0414	0.3459	0.3459
Echinococcus multilocularis	SH2 motif	0.0414	0.3459	0.3459
Echinococcus granulosus	tyrosine kinase	0.0697	1	1
Trypanosoma brucei	STE/STE11 serine/threonine-protein kinase, putative	0.0284	0.0453	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0697	1	1
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0284	0.0453	0.5
Loa Loa (eye worm)	TK/ALK protein kinase	0.0284	0.0453	0.0453
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0414	0.3459	0.3459
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Brugia malayi	Variant SH3 domain containing protein	0.0414	0.3459	0.3148
Loa Loa (eye worm)	TK/FER protein kinase	0.0697	1	1
Toxoplasma gondii	protein kinase domain-containing protein	0.0284	0.0453	0.5
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0284	0.0453	0.0453
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0414	0.3459	0.3459
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Brugia malayi	Variant SH3 domain containing protein	0.0414	0.3459	0.3148
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Echinococcus multilocularis	epidermal growth factor receptor	0.0284	0.0453	0.0453
Echinococcus multilocularis	ephrin type A receptor 4 A	0.0284	0.0453	0.0453
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0697	1	1
Brugia malayi	SH2 domain containing protein	0.0414	0.3459	0.3148
Schistosoma mansoni	protein tyrosine phosphatase n11 (shp2)	0.0414	0.3459	0.3459
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0284	0.0453	0.0453
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0284	0.0453	0.0453
Echinococcus multilocularis	SH2 domain containing adapter protein F	0.0414	0.3459	0.3459
Brugia malayi	SH2 domain containing protein	0.0414	0.3459	0.3148
Trichomonas vaginalis	conserved hypothetical protein	0.0284	0.0453	0.5
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0697	1	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0697	1	1
Echinococcus granulosus	SH2 motif	0.0414	0.3459	0.3459
Echinococcus granulosus	protein kinase	0.0284	0.0453	0.0453
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Schistosoma mansoni	protein kinase	0.0284	0.0453	0.0453
Loa Loa (eye worm)	TK protein kinase	0.0697	1	1
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Echinococcus multilocularis	growth factor receptor bound protein 2	0.0414	0.3459	0.3459
Schistosoma mansoni	adapter molecule crk	0.0414	0.3459	0.3459
Echinococcus multilocularis	tyrosine protein kinase Blk	0.0697	1	1
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0697	1	1
Loa Loa (eye worm)	hypothetical protein	0.0414	0.3459	0.3459
Loa Loa (eye worm)	STAT protein	0.0414	0.3459	0.3459
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Echinococcus granulosus	activated cdc42 kinase 1	0.0284	0.0453	0.0453
Schistosoma mansoni	protein kinase	0.0284	0.0453	0.0453
Schistosoma mansoni	tyrosine kinase	0.0284	0.0453	0.0453
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.0414	0.3459	0.3459
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.0697	1	1
Giardia lamblia	Kinase, NEK	0.0284	0.0453	0.5
Loa Loa (eye worm)	hypothetical protein	0.0284	0.0453	0.0453
Loa Loa (eye worm)	TK/EGFR protein kinase	0.0284	0.0453	0.0453
Onchocerca volvulus		0.0697	1	1
Brugia malayi	hypothetical protein	0.0414	0.3459	0.3148
Echinococcus multilocularis	protein KINase family member (kin 25)	0.0284	0.0453	0.0453
Echinococcus multilocularis	kinase suppressor of Ras 1	0.0284	0.0453	0.0453
Echinococcus granulosus	SH2 motif	0.0414	0.3459	0.3459
Loa Loa (eye worm)	TK protein kinase	0.0284	0.0453	0.0453
Echinococcus multilocularis	transfer RNA-Thr	0.0284	0.0453	0.0453
Loa Loa (eye worm)	TK/FER protein kinase	0.0697	1	1
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Brugia malayi	STAT protein, DNA binding domain containing protein	0.0414	0.3459	0.3148
Echinococcus multilocularis	activated cdc42 kinase 1	0.0284	0.0453	0.0453
Trypanosoma brucei	Flagellum attachment zone protein 20	0.0284	0.0453	0.5
Loa Loa (eye worm)	hypothetical protein	0.0414	0.3459	0.3459
Echinococcus granulosus	mitogen-activated protein kinase kinase kinase 9	0.0284	0.0453	0.0453
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.0284	0.0453	0.0453
Loa Loa (eye worm)	TK/FER protein kinase	0.0284	0.0453	0.0453
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0284	0.0453	0.0453
Echinococcus granulosus	epidermal growth factor receptor	0.0284	0.0453	0.0453
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Echinococcus granulosus	c src tyrosine kinase	0.0697	1	1
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Loa Loa (eye worm)	RhoGAP domain-containing protein	0.0414	0.3459	0.3459
Schistosoma mansoni	protein kinase	0.0284	0.0453	0.0453
Onchocerca volvulus		0.0697	1	1
Loa Loa (eye worm)	hypothetical protein	0.0284	0.0453	0.0453
Schistosoma mansoni	tyrosine kinase	0.0284	0.0453	0.0453
Echinococcus granulosus	suppressor of cytokine signaling 6	0.0414	0.3459	0.3459
Echinococcus granulosus	fibroblast growth factor receptor 4	0.0284	0.0453	0.0453
Loa Loa (eye worm)	hypothetical protein	0.0284	0.0453	0.0453
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.0697	1	1
Loa Loa (eye worm)	TK/FAK protein kinase	0.0284	0.0453	0.0453
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Echinococcus multilocularis	activin receptor type	0.0284	0.0453	0.0453
Echinococcus multilocularis	tyrosine protein kinase csk	0.0284	0.0453	0.0453
Onchocerca volvulus		0.0414	0.3459	0.3148
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Loa Loa (eye worm)	TK/DDR protein kinase	0.0284	0.0453	0.0453
Echinococcus multilocularis	atrial natriuretic peptide receptor 1	0.0284	0.0453	0.0453
Trichomonas vaginalis	protein kinase atn1, putative	0.0284	0.0453	0.5
Echinococcus granulosus	activin receptor type	0.0284	0.0453	0.0453
Schistosoma mansoni	protein kinase	0.0284	0.0453	0.0453
Schistosoma mansoni	tyrosine kinase	0.0697	1	1
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Schistosoma mansoni	tyrosine kinase	0.0284	0.0453	0.0453
Loa Loa (eye worm)	SH2 domain-containing protein	0.0414	0.3459	0.3459
Loa Loa (eye worm)	hypothetical protein	0.0414	0.3459	0.3459
Echinococcus granulosus	dual specificity testis-specific protein kinase	0.0284	0.0453	0.0453
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Loa Loa (eye worm)	TK/KIN6 protein kinase	0.0284	0.0453	0.0453
Trichomonas vaginalis	CAMK family protein kinase	0.0284	0.0453	0.5
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.0697	1	1
Brugia malayi	Sex muscle abnormal protein 5	0.0414	0.3459	0.3148
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Echinococcus granulosus	SHC transforming protein 3	0.0414	0.3459	0.3459
Echinococcus granulosus	tyrosine kinase	0.0284	0.0453	0.0453
Echinococcus multilocularis	basic fibroblast growth factor receptor 1 A	0.0284	0.0453	0.0453
Echinococcus granulosus	tyrosine protein kinase Srms	0.0697	1	1
Schistosoma mansoni	GTPase activating protein	0.0414	0.3459	0.3459
Echinococcus granulosus	SH2 domain containing protein 7	0.0414	0.3459	0.3459
Plasmodium falciparum	tyrosine kinase-like protein	0.0284	0.0453	0.5
Loa Loa (eye worm)	hypothetical protein	0.0414	0.3459	0.3459
Schistosoma mansoni	tyrosine kinase	0.0284	0.0453	0.0453
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.0697	1	1
Onchocerca volvulus		0.0697	1	1
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.0697	1	1
Echinococcus granulosus	signal transduction protein lnk realted	0.0414	0.3459	0.3459
Plasmodium falciparum	protein kinase, putative	0.0284	0.0453	0.5
Echinococcus multilocularis	epidermal growth factor receptor	0.0284	0.0453	0.0453
Schistosoma mansoni	tyrosine kinase	0.0284	0.0453	0.0453
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Schistosoma mansoni	tyrosine kinase	0.0284	0.0453	0.0453
Loa Loa (eye worm)	TK/INSR protein kinase	0.0284	0.0453	0.0453
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.0697	1	1
Echinococcus multilocularis	protein tyrosine kinase	0.0284	0.0453	0.0453
Loa Loa (eye worm)	TK/FER protein kinase	0.0697	1	1
Echinococcus granulosus	growth factor receptor bound protein 2	0.0414	0.3459	0.3459
Schistosoma mansoni	tyrosine kinase	0.0284	0.0453	0.0453
Brugia malayi	SH2 domain containing protein	0.0414	0.3459	0.3148
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.0414	0.3459	0.3459
Trypanosoma brucei	Pseudokinase, putative	0.0284	0.0453	0.5
Schistosoma mansoni	tyrosine protein kinase	0.0284	0.0453	0.0453
Schistosoma mansoni	tyrosine kinase	0.0284	0.0453	0.0453
Loa Loa (eye worm)	TK protein kinase	0.0284	0.0453	0.0453
Echinococcus granulosus	natriuretic peptide receptor 1	0.0284	0.0453	0.0453
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Schistosoma mansoni	tyrosine kinase	0.0697	1	1
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Giardia lamblia	Kinase, NEK	0.0284	0.0453	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Echinococcus multilocularis	tyrosine protein kinase csk	0.0284	0.0453	0.0453
Echinococcus granulosus	tyrosine kinase	0.0697	1	1
Echinococcus granulosus	insulin growth factor 1 receptor beta	0.0284	0.0453	0.0453
Trichomonas vaginalis	br serine/threonine-protein kinase, putative	0.0284	0.0453	0.5
Brugia malayi	Variant SH3 domain containing protein	0.0414	0.3459	0.3148
Echinococcus granulosus	tyrosine protein kinase shark	0.0697	1	1
Schistosoma mansoni	serine/threonine protein kinase	0.0284	0.0453	0.0453
Loa Loa (eye worm)	TKL/MLK/HH498 protein kinase	0.0284	0.0453	0.0453
Loa Loa (eye worm)	hypothetical protein	0.0284	0.0453	0.0453
Echinococcus multilocularis	tyrosine protein kinase shark	0.0697	1	1
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Schistosoma mansoni	tyrosine kinase	0.0284	0.0453	0.0453
Loa Loa (eye worm)	TK/FER protein kinase	0.0284	0.0453	0.0453
Schistosoma mansoni	hypothetical protein	0.0284	0.0453	0.0453
Echinococcus multilocularis	suppressor of cytokine signaling 6	0.0414	0.3459	0.3459
Echinococcus granulosus	tyrosine protein kinase Src64B	0.0697	1	1
Schistosoma mansoni	tensin	0.0414	0.3459	0.3459
Loa Loa (eye worm)	hypothetical protein	0.0284	0.0453	0.0453
Loa Loa (eye worm)	sex muscle abnormal protein 5	0.0414	0.3459	0.3459
Echinococcus granulosus	tensin	0.0414	0.3459	0.3459
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Echinococcus multilocularis	tyrosine protein kinase Abl	0.0697	1	1
Loa Loa (eye worm)	hypothetical protein	0.0414	0.3459	0.3459
Brugia malayi	hypothetical protein	0.0697	1	1
Loa Loa (eye worm)	hypothetical protein	0.0697	1	1
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0284	0.0453	0.0453
Brugia malayi	SH2 domain containing protein	0.0414	0.3459	0.3148
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0284	0.0453	0.0453
Schistosoma mansoni	protein kinase	0.0284	0.0453	0.0453
Echinococcus granulosus	N chimaerin	0.0414	0.3459	0.3459
Schistosoma mansoni	tyrosine kinase	0.0284	0.0453	0.0453
Echinococcus multilocularis	signal transduction protein lnk realted	0.0414	0.3459	0.3459
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0284	0.0453	0.0453
Entamoeba histolytica	SH2 domain containing protein	0.0414	0.3459	0.3148
Echinococcus granulosus	tyrosine protein kinase HCK	0.0284	0.0453	0.0453
Brugia malayi	Tyrosine-protein kinase abl-1	0.0697	1	1
Echinococcus multilocularis	insulin receptor	0.0284	0.0453	0.0453
Loa Loa (eye worm)	TK/FER protein kinase	0.0284	0.0453	0.0453
Onchocerca volvulus		0.0414	0.3459	0.3148
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Onchocerca volvulus		0.0697	1	1
Onchocerca volvulus		0.0414	0.3459	0.3148
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Schistosoma mansoni	tyrosine kinase	0.0284	0.0453	0.0453
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Schistosoma mansoni	src-type protein tyrosine kinase-related	0.0284	0.0453	0.0453
Onchocerca volvulus		0.0414	0.3459	0.3148
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Brugia malayi	SH2 domain containing protein	0.0414	0.3459	0.3148
Schistosoma mansoni	tyrosine kinase	0.0284	0.0453	0.0453
Echinococcus granulosus	tyrosine protein kinase csk	0.0284	0.0453	0.0453
Loa Loa (eye worm)	TK/ABL protein kinase	0.0697	1	1
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Schistosoma mansoni	tyrosine-protein kinase zap-70	0.0414	0.3459	0.3459
Loa Loa (eye worm)	SRC-1	0.0697	1	1
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0697	1	1
Loa Loa (eye worm)	SH2 domain-containing protein	0.0414	0.3459	0.3459
Brugia malayi	Protein kinase domain containing protein	0.0697	1	1
Schistosoma mansoni	tensin	0.0414	0.3459	0.3459
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0284	0.0453	0.0453
Trichomonas vaginalis	conserved hypothetical protein	0.0284	0.0453	0.5
Echinococcus multilocularis	guanine nucleotide exchange factor VAV2	0.0414	0.3459	0.3459
Schistosoma mansoni	protein kinase	0.0284	0.0453	0.0453
Echinococcus multilocularis	tyrosine protein kinase HCK	0.0284	0.0453	0.0453
Schistosoma mansoni	shc transforming protein	0.0414	0.3459	0.3459
Loa Loa (eye worm)	hypothetical protein	0.0414	0.3459	0.3459
Trichomonas vaginalis	conserved hypothetical protein	0.0284	0.0453	0.5
Loa Loa (eye worm)	TK/ROR protein kinase	0.0284	0.0453	0.0453
Echinococcus granulosus	tyrosine protein kinase Fes:Fps	0.0284	0.0453	0.0453
Schistosoma mansoni	suppressor of cytokine signaling	0.0414	0.3459	0.3459
Trichomonas vaginalis	conserved hypothetical protein	0.0284	0.0453	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Echinococcus multilocularis	tyrosine kinase	0.0697	1	1
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0284	0.0453	0.0453
Trichomonas vaginalis	conserved hypothetical protein	0.0284	0.0453	0.5
Schistosoma mansoni	tyrosine kinase	0.0284	0.0453	0.0453
Loa Loa (eye worm)	hypothetical protein	0.0414	0.3459	0.3459
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0697	1	1
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0697	1	1
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Echinococcus multilocularis	SHC transforming protein 3	0.0414	0.3459	0.3459
Loa Loa (eye worm)	TK protein kinase	0.0284	0.0453	0.0453
Schistosoma mansoni	protein kinase	0.0284	0.0453	0.0453
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0284	0.0453	0.5
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0284	0.0453	0.0453
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Schistosoma mansoni	tyrosine kinase	0.0284	0.0453	0.0453
Echinococcus granulosus	tyrosine protein kinase ABL1	0.0697	1	1
Echinococcus granulosus	tyrosine protein kinase Blk	0.0697	1	1
Schistosoma mansoni	tyrosine kinase	0.0284	0.0453	0.0453
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Echinococcus granulosus	tyrosine protein kinase pr2	0.0284	0.0453	0.0453
Schistosoma mansoni	protein kinase	0.0284	0.0453	0.0453
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Schistosoma mansoni	hypothetical protein	0.0414	0.3459	0.3459
Echinococcus granulosus	guanine nucleotide exchange factor VAV2	0.0414	0.3459	0.3459
Echinococcus multilocularis	dual specificity testis specific protein kinase	0.0284	0.0453	0.0453
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0697	1	1
Brugia malayi	Tensin	0.0414	0.3459	0.3148
Schistosoma mansoni	tyrosine kinase	0.0697	1	1
Echinococcus multilocularis	tyrosine protein kinase csk	0.0284	0.0453	0.0453
Echinococcus multilocularis	FL cytokine receptor	0.0284	0.0453	0.0453
Giardia lamblia	Kinase	0.0284	0.0453	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Echinococcus granulosus	tyrosine protein kinase Lyn	0.0697	1	1
Loa Loa (eye worm)	TK/EPH protein kinase	0.0284	0.0453	0.0453
Echinococcus multilocularis	integrin linked protein kinase	0.0284	0.0453	0.0453
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.0414	0.3459	0.3148
Schistosoma mansoni	serine/threonine protein kinase	0.0284	0.0453	0.0453
Schistosoma mansoni	tyrosine kinase	0.0284	0.0453	0.0453
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0284	0.0453	0.5
Loa Loa (eye worm)	hypothetical protein	0.0284	0.0453	0.0453
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0697	1	1
Echinococcus granulosus	tyrosine protein kinase csk	0.0284	0.0453	0.0453
Loa Loa (eye worm)	hypothetical protein	0.0414	0.3459	0.3459
Echinococcus granulosus	insulin receptor	0.0284	0.0453	0.0453
Schistosoma mansoni	tyrosine kinase	0.0697	1	1
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0414	0.3459	0.3459
Echinococcus multilocularis	c src tyrosine kinase	0.0697	1	1
Echinococcus multilocularis	insulin growth factor 1 receptor beta	0.0284	0.0453	0.0453
Loa Loa (eye worm)	hypothetical protein	0.0414	0.3459	0.3459
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Schistosoma mansoni	tyrosine kinase	0.0284	0.0453	0.0453
Schistosoma mansoni	tyrosine kinase	0.0284	0.0453	0.0453
Echinococcus multilocularis	SH2 domain containing protein 7	0.0414	0.3459	0.3459
Schistosoma mansoni	nck2/grb4	0.0414	0.3459	0.3459
Loa Loa (eye worm)	TK/FER protein kinase	0.0284	0.0453	0.0453
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0284	0.0453	0.5
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.0697	1	1
Loa Loa (eye worm)	TK protein kinase	0.0284	0.0453	0.0453
Echinococcus multilocularis	natriuretic peptide receptor 1	0.0284	0.0453	0.0453
Echinococcus multilocularis	tyrosine protein kinase Fes:Fps	0.0284	0.0453	0.0453
Loa Loa (eye worm)	hypothetical protein	0.0414	0.3459	0.3459
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Schistosoma mansoni	tensin-related	0.0414	0.3459	0.3459
Toxoplasma gondii	calcium dependent protein kinase CDPK8	0.0284	0.0453	0.5
Schistosoma mansoni	tensin	0.0414	0.3459	0.3459
Loa Loa (eye worm)	protein kinase domain-containing protein	0.0284	0.0453	0.0453
Plasmodium falciparum	tyrosine kinase-like protein	0.0284	0.0453	0.5
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0284	0.0453	0.0453
Trypanosoma cruzi	protein kinase, putative	0.0284	0.0453	0.5
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0284	0.0453	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Echinococcus multilocularis	heat shock protein 70	0.0284	0.0453	0.0453
Echinococcus granulosus	macrophage colony stimulating factor 1 receptor	0.0284	0.0453	0.0453
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0697	1	1
Echinococcus granulosus	melanoma receptor tyrosine protein kinase	0.0284	0.0453	0.0453
Echinococcus multilocularis	tensin	0.0414	0.3459	0.3459
Onchocerca volvulus	Suppressor of cytokine signaling 7 homolog	0.0414	0.3459	0.3148
Loa Loa (eye worm)	TK/Met protein kinase	0.0284	0.0453	0.0453
Loa Loa (eye worm)	cytokine inducible SH2-containing protein 5	0.0414	0.3459	0.3459
Trichomonas vaginalis	conserved hypothetical protein	0.0284	0.0453	0.5
Trichomonas vaginalis	TK family protein kinase	0.0284	0.0453	0.5
Trypanosoma cruzi	protein kinase, putative	0.0284	0.0453	0.5
Schistosoma mansoni	protein kinase	0.0284	0.0453	0.0453
Echinococcus multilocularis	tyrosine protein kinase pr2	0.0284	0.0453	0.0453
Brugia malayi	SH2 domain containing protein	0.0414	0.3459	0.3148
Echinococcus granulosus	ephrin type A receptor 4 A	0.0284	0.0453	0.0453
Loa Loa (eye worm)	hypothetical protein	0.0284	0.0453	0.0453
Schistosoma mansoni	chimerin-related rho-gtpase-activating protein	0.0414	0.3459	0.3459
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Schistosoma mansoni	tyrosine kinase	0.0284	0.0453	0.0453
Leishmania major	protein kinase, putative	0.0284	0.0453	0.5
Loa Loa (eye worm)	serine/threonine protein kinase	0.0284	0.0453	0.0453
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Onchocerca volvulus		0.0697	1	1
Giardia lamblia	Protein 21.1	0.0284	0.0453	0.5
Echinococcus granulosus	suppressor of cytokine signaling 7	0.0414	0.3459	0.3459
Loa Loa (eye worm)	TK protein kinase	0.0284	0.0453	0.0453
Loa Loa (eye worm)	TK/FER protein kinase	0.0697	1	1
Trichomonas vaginalis	STE family protein kinase	0.0284	0.0453	0.5
Loa Loa (eye worm)	hypothetical protein	0.0284	0.0453	0.0453
Echinococcus granulosus	3'partial\|retinal guanylyl cyclase 2	0.0284	0.0453	0.0453
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0284	0.0453	0.5
Echinococcus granulosus	basic fibroblast growth factor receptor 1 A	0.0284	0.0453	0.0453
Schistosoma mansoni	signal transduction protein lnk-related	0.0414	0.3459	0.3459
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Echinococcus multilocularis	N chimaerin	0.0414	0.3459	0.3459
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0697	1	1
Entamoeba histolytica	protein kinase, putative	0.0414	0.3459	0.3148
Echinococcus granulosus	hypothetical protein	0.0414	0.3459	0.3459
Brugia malayi	SH2 domain containing protein	0.0414	0.3459	0.3148
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0284	0.0453	0.0453
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0697	1	1
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Echinococcus multilocularis	tyrosine protein kinase csk	0.0284	0.0453	0.0453
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase abl1	0.0414	0.3459	0.3459
Echinococcus granulosus	tyrosine protein kinase	0.0284	0.0453	0.0453
Echinococcus granulosus	mitogen activated protein kinase kinase kinase	0.0284	0.0453	0.0453
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0284	0.0453	0.0453
Echinococcus multilocularis	receptor type guanylyl cyclase	0.0284	0.0453	0.0453
Loa Loa (eye worm)	hypothetical protein	0.0284	0.0453	0.0453
Loa Loa (eye worm)	hypothetical protein	0.0414	0.3459	0.3459
Plasmodium falciparum	protein kinase, putative	0.0284	0.0453	0.5
Loa Loa (eye worm)	TK/RYK protein kinase	0.0284	0.0453	0.0453
Echinococcus multilocularis	fibroblast growth factor receptor 4	0.0284	0.0453	0.0453
Schistosoma mansoni	serine/threonine protein kinase	0.0284	0.0453	0.0453
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Echinococcus granulosus	atrial natriuretic peptide receptor 1	0.0284	0.0453	0.0453
Loa Loa (eye worm)	hypothetical protein	0.0414	0.3459	0.3459
Schistosoma mansoni	tyrosine kinase	0.0284	0.0453	0.0453
Loa Loa (eye worm)	TK/CSK protein kinase	0.0284	0.0453	0.0453
Brugia malayi	cytokine inducible SH2-containing protein 5	0.0414	0.3459	0.3148
Loa Loa (eye worm)	hypothetical protein	0.0284	0.0453	0.0453
Loa Loa (eye worm)	TK/FER protein kinase	0.0697	1	1
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0284	0.0453	0.0453
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.0697	1	1
Echinococcus multilocularis	SH2 motif	0.0414	0.3459	0.3459
Echinococcus multilocularis		0.0414	0.3459	0.3459
Echinococcus granulosus	tensin C1 domain containing phosphatase	0.0414	0.3459	0.3459
Echinococcus multilocularis	SH2 motif	0.0414	0.3459	0.3459
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0284	0.0453	0.0453
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0284	0.0453	0.5
Brugia malayi	Protein kinase domain containing protein	0.0697	1	1
Trichomonas vaginalis	AGC family protein kinase	0.0284	0.0453	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0284	0.0453	0.0453
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0414	0.3459	0.3459
Trypanosoma brucei	protein kinase, putative	0.0284	0.0453	0.5
Trichomonas vaginalis	serine-threonine protein kinase, putative	0.0284	0.0453	0.5
Echinococcus granulosus	receptor type guanylyl cyclase	0.0284	0.0453	0.0453
Loa Loa (eye worm)	hypothetical protein	0.0284	0.0453	0.0453
Loa Loa (eye worm)	TK/ACK protein kinase	0.0284	0.0453	0.0453
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0284	0.0453	0.0453
Loa Loa (eye worm)	TK/FER protein kinase	0.0697	1	1
Echinococcus granulosus	activated cdc42 kinase 1	0.0284	0.0453	0.0453
Schistosoma mansoni	suppressor of cytokine signaling	0.0414	0.3459	0.3459
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Loa Loa (eye worm)	TKL/MLK/ILK protein kinase	0.0284	0.0453	0.0453
Loa Loa (eye worm)	TKL/RAF/KSR protein kinase	0.0284	0.0453	0.0453
Brugia malayi	SH2 domain containing protein	0.0697	1	1
Schistosoma mansoni	vav2	0.0414	0.3459	0.3459
Schistosoma mansoni	tyrosine kinase	0.0284	0.0453	0.0453
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.0697	1	1
Echinococcus multilocularis	protein kinase	0.0284	0.0453	0.0453
Brugia malayi	protein-tyrosine kinase	0.0697	1	1
Onchocerca volvulus		0.0414	0.3459	0.3148
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.0697	1	1
Schistosoma mansoni	tyrosine kinase	0.0697	1	1
Echinococcus multilocularis	tyrosine protein kinase Srms	0.0697	1	1
Loa Loa (eye worm)	TKL/RAF/RAF protein kinase	0.0284	0.0453	0.0453
Schistosoma mansoni	protein kinase	0.0284	0.0453	0.0453
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Leishmania major	hypothetical protein, conserved	0.0284	0.0453	0.5
Loa Loa (eye worm)	hypothetical protein	0.0414	0.3459	0.3459
Loa Loa (eye worm)	TK/FER protein kinase	0.0284	0.0453	0.0453
Loa Loa (eye worm)	TKL/MLK/TAK1 protein kinase	0.0284	0.0453	0.0453
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0284	0.0453	0.0453
Schistosoma mansoni	serine/threonine RGC	0.0284	0.0453	0.0453
Schistosoma mansoni	tyrosine kinase	0.0697	1	1
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0284	0.0453	0.5
Schistosoma mansoni	growth factor receptor-bound protein	0.0414	0.3459	0.3459
Schistosoma mansoni	hypothetical protein	0.0414	0.3459	0.3459
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0697	1	1
Echinococcus multilocularis	suppressor of cytokine signaling 7	0.0414	0.3459	0.3459
Loa Loa (eye worm)	TK protein kinase	0.0284	0.0453	0.0453
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0284	0.0453	0.0453
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0284	0.0453	0.0453
Echinococcus multilocularis	NCK adaptor protein	0.0414	0.3459	0.3459

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	= 0.26 uM	In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbits	ChEMBL.	8230120
IC50 (binding)	= 0.26 uM	In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbits	ChEMBL.	8230120

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

PubChem: 14977531

Bibliographic References

1 literature reference was collected for this gene.

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Detailed information for compound 183312