Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | cholesteryl ester transfer protein, plasma | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | hypothetical protein | 0.0023 | 0.0103 | 0.0464 |
Loa Loa (eye worm) | hypothetical protein | 0.0215 | 0.222 | 1 |
Brugia malayi | LBP / BPI / CETP family, C-terminal domain containing protein | 0.0041 | 0.0294 | 0.1326 |
Mycobacterium ulcerans | bifunctional nicotinate-nucleotide adenylyltransferase NadD/hypothetical protein | 0.0346 | 0.3666 | 1 |
Treponema pallidum | hypothetical protein | 0.0346 | 0.3666 | 1 |
Onchocerca volvulus | 0.0041 | 0.0294 | 0.1215 | |
Schistosoma mansoni | rab6-interacting | 0.0209 | 0.2153 | 1 |
Brugia malayi | hypothetical protein | 0.0209 | 0.2153 | 0.9698 |
Schistosoma mansoni | inositol monophosphatase | 0.0043 | 0.0323 | 0.1165 |
Schistosoma mansoni | lipoxygenase | 0.0209 | 0.2153 | 1 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0209 | 0.2153 | 1 |
Onchocerca volvulus | 0.0041 | 0.0294 | 0.1215 | |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0043 | 0.0323 | 0.1348 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0037 | 0.0168 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.0323 | 1 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0043 | 0.0323 | 1 |
Mycobacterium leprae | PROBABLE NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE NADD (DEAMIDO-NAD(+) PYROPHOSPHORYLASE) (DEAMIDO-NAD(+) DIPHOSPHORYLASE) (NIC | 0.0346 | 0.3666 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0021 | 0.0081 | 0.2523 |
Plasmodium vivax | nicotinate-nucleotide adenylyltransferase, putative | 0.0346 | 0.3666 | 1 |
Onchocerca volvulus | 0.0209 | 0.2153 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0037 | 0.0168 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0043 | 0.0323 | 0.1348 |
Brugia malayi | Inositol-1 | 0.0043 | 0.0323 | 0.1454 |
Loa Loa (eye worm) | LBP/BPI/CETP family domain-containing protein | 0.0023 | 0.0103 | 0.0464 |
Loa Loa (eye worm) | LBP/BPI/CETP family domain-containing protein | 0.0023 | 0.0103 | 0.0464 |
Onchocerca volvulus | 0.0041 | 0.0294 | 0.1215 | |
Plasmodium falciparum | LCCL domain-containing protein | 0.0209 | 0.2153 | 0.578 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0021 | 0.0081 | 0.2523 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0021 | 0.0081 | 0.0208 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0043 | 0.0323 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0103 | 0.0464 |
Brugia malayi | LBP/BPI | 0.0017 | 0.0037 | 0.0168 |
Schistosoma mansoni | polycystin 1-related | 0.0209 | 0.2153 | 1 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0043 | 0.0323 | 0.0881 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0209 | 0.2153 | 1 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0021 | 0.0081 | 0.2523 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0037 | 0.0168 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0209 | 0.2153 | 0.2089 |
Brugia malayi | hypothetical protein | 0.0209 | 0.2153 | 0.9698 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0037 | 0.0168 |
Brugia malayi | LBP / BPI / CETP family, N-terminal domain containing protein | 0.0041 | 0.0294 | 0.1326 |
Onchocerca volvulus | 0.0041 | 0.0294 | 0.1215 | |
Schistosoma mansoni | loxhd1 | 0.0209 | 0.2153 | 1 |
Echinococcus multilocularis | RUN | 0.0209 | 0.2153 | 0.2089 |
Brugia malayi | Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog | 0.0215 | 0.222 | 1 |
Loa Loa (eye worm) | LBP/BPI/CETP family domain-containing protein | 0.0041 | 0.0294 | 0.1326 |
Brugia malayi | hypothetical protein | 0.0023 | 0.0103 | 0.0464 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.0323 | 1 |
Loa Loa (eye worm) | doublecortin family protein | 0.0209 | 0.2153 | 0.9698 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0021 | 0.0081 | 0.0208 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0021 | 0.0081 | 0.5 |
Mycobacterium tuberculosis | Probable nicotinate-nucleotide adenylyltransferase NadD (deamido-NAD(+) pyrophosphorylase) (deamido-NAD(+) diphosphorylase) (nic | 0.0346 | 0.3666 | 1 |
Onchocerca volvulus | 0.0041 | 0.0294 | 0.1215 | |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0039 | 0.0273 | 0.0534 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0294 | 0.1326 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0043 | 0.0323 | 0.1165 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0209 | 0.2153 | 1 |
Brugia malayi | LBP / BPI / CETP family, C-terminal domain containing protein | 0.0023 | 0.0103 | 0.0464 |
Onchocerca volvulus | 0.0209 | 0.2153 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0103 | 0.0464 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0043 | 0.0323 | 1 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0209 | 0.2153 | 0.578 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.0323 | 1 |
Echinococcus granulosus | RUN | 0.0209 | 0.2153 | 1 |
Onchocerca volvulus | 0.0023 | 0.0103 | 0.0311 | |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0043 | 0.0323 | 0.0243 |
Onchocerca volvulus | 0.0023 | 0.0103 | 0.0311 | |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0021 | 0.0081 | 0.0222 |
Brugia malayi | LBP / BPI / CETP family, N-terminal domain containing protein | 0.0041 | 0.0294 | 0.1326 |
Schistosoma mansoni | inositol monophosphatase | 0.0043 | 0.0323 | 0.1165 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0209 | 0.2156 | 1 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0209 | 0.2153 | 0.2089 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0103 | 0.0464 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 0.2153 | 0.9698 |
Onchocerca volvulus | 0.0041 | 0.0294 | 0.1215 | |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0043 | 0.0323 | 0.1348 |
Plasmodium falciparum | nicotinamide/nicotinic acid mononucleotide adenylyltransferase | 0.0346 | 0.3666 | 1 |
Brugia malayi | Doublecortin family protein | 0.0209 | 0.2153 | 0.9698 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0021 | 0.0081 | 0.0367 |
Brugia malayi | LBP / BPI / CETP family, C-terminal domain containing protein | 0.0023 | 0.0103 | 0.0464 |
Onchocerca volvulus | 0.0041 | 0.0294 | 0.1215 | |
Brugia malayi | LBP / BPI / CETP family, C-terminal domain containing protein | 0.0023 | 0.0103 | 0.0464 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.0323 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0209 | 0.2153 | 1 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0209 | 0.2153 | 0.2089 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0103 | 0.0464 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 0.2153 | 0.9698 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0103 | 0.0464 |
Loa Loa (eye worm) | inositol-1 | 0.0043 | 0.0323 | 0.1454 |
Onchocerca volvulus | 0.0041 | 0.0294 | 0.1215 | |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0021 | 0.0081 | 0.0367 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0021 | 0.0081 | 0.2523 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0037 | 0.0168 |
Schistosoma mansoni | rab6-interacting | 0.0209 | 0.2153 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.