Detailed view for ML1454c

Basic information

TDR Targets ID: 256815
Mycobacterium leprae, PROBABLE NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE NADD (DEAMIDO-NAD(+) PYROPHOSPHORYLASE) (DEAMIDO-NAD(+) DIPHOSPHORYLASE) (NIC
Source Database / ID:  Leproma 

pI: 5.5116 | Length (AA): 214 | MW (Da): 23700 | Paralog Number: 0

Signal peptide: N | GPI Anchor: | Predicted trans-membrane segments: 0

Druggability Group : DG1

Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable

Pfam domains

PF01467   Cytidylyltransferase-like

Gene Ontology

Mouse over links to read term descriptions.
GO:0016779   nucleotidyltransferase activity  
GO:0003824   catalytic activity  
GO:0009435   NAD biosynthetic process  
GO:0009058   biosynthetic process  

Metabolic Pathways

Nicotinate and nicotinamide metabolism (KEGG)
Global map (KEGG)

Structural information

Modbase 3D models:

There are 2 models calculated for this protein. More info on these models, including the models themselves is available at: Modbase

Target Beg Target End Template Template Beg Template End Identity Evalue Model Score MPQS zDope
1 191 5vir (A) 12 201 76.00 0 1 1.75722 -1.11
1 191 4s1o (A) 9 199 89.00 0 1 1.85522 -1.09

Help me make sense of these data.

Target Beg: first modeled residue
Target End: last modeled residue
Template: template structure used for modelling (PDB accession and chain)
Template Beg: first template residue in target-template alignment
Template End: last template residue in target-template alignment
Identity: sequence identity
Evalue: E value for target-template hit
Model Score: GA341 score (>0.7 for reliable model)
MPQS: ModPipe Quality Score (>1.1 for reliable model)
zDope: zDope Score (negative for reliable model)

A more detailed description of these scores is available at the Modbase Model Evaluation Help Pages, and in the papers referenced therein.

PDB Structures:

No structure availble in the PDB for this protein

Expression

No expression data available for this gene

Orthologs

Ortholog group members (OG5_131883)

Species Accession Gene Product
Babesia bovis BBOV_III002480   cytidylyltransferase family protein
Escherichia coli b0639   nicotinic acid mononucleotide adenylyltransferase, NAD(P)-dependent
Mycobacterium leprae ML1454c   PROBABLE NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE NADD (DEAMIDO-NAD(+) PYROPHOSPHORYLASE) (DEAMIDO-NAD(+) DIPHOSPHORYLASE) (NIC
Mycobacterium tuberculosis Rv2421c   Probable nicotinate-nucleotide adenylyltransferase NadD (deamido-NAD(+) pyrophosphorylase) (deamido-NAD(+) diphosphorylase) (nic
Mycobacterium ulcerans MUL_3692   bifunctional nicotinate-nucleotide adenylyltransferase NadD/hypothetical protein
Plasmodium berghei PBANKA_1342800   nicotinamide/nicotinic acid mononucleotide adenylyltransferase, putative
Plasmodium falciparum PF3D7_1327600   nicotinamide/nicotinic acid mononucleotide adenylyltransferase
Plasmodium knowlesi PKNH_1201000   nicotinamide/nicotinic acid mononucleotide adenylyltransferase, putative
Plasmodium vivax PVX_116500   nicotinate-nucleotide adenylyltransferase, putative
Plasmodium yoelii PY06728   Predicted nucleotidyltransferase, putative
Treponema pallidum TP0741   hypothetical protein
Theileria parva TP03_0631   hypothetical protein, conserved

Essentiality

ML1454c has one or more orthologs with essentiality data
Gene/Ortholog Organism Phenotype Source Study
mtu2463 Mycobacterium tuberculosis essential nmpdr
b0639 Escherichia coli essential goodall
PBANKA_1342800 Plasmodium berghei Slow plasmo
Show/Hide essentiality data references
  • shigen Profiling of E. coli Chromosome (PEC) National Institute of Genetics, Japan
  • yeastgenome Systematic deletion of yeast genes Saccharomyces Genome Database
  • goodall The Essential Genome of Escherichia coli K-12 (Transposon directed high-throughput mutagenesis) Goodall, Emily CA, et al. "The essential genome of Escherichia coli K-12." mBio 9.1 (2018): e02096-17.
  • gerdes Experimental determination and system-level analysis of essential genes in E. coli MG1655 Gerdes et al., J Bacteriol. 2003 185:5673-84
  • alsford High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome Genome Res 2011, 21:915-924
  • nmpdr Genome-scale essentiality datasets from published studies (M. tuberculosis) National Microbial Pathogen Data Resource
  • neb C. elegans RNAi phenotypes Data obtained from Wormbase WS150, curated by K. Chaudary and T. Carlow, New England Biolabs
  • plasmo Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes. Bushell, Ellen, et al. "Functional profiling of a Plasmodium genome reveals an abundance of essential genes." Cell 170.2 (2017): 260-272.
  • keio Systematic single-gene knock-out mutants of E. coli K12 The Keio Collection
  • sidik A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes. Sidik, Saima M., et al. "A genome-wide CRISPR screen in toxoplasma identifies essential apicomplexan genes." Cell 166.6 (2016): 1423-1435.
  • wormbase C. elegans RNAi experiments WormBase web site, http://www.wormbase.org, release WS170
  • blattner Systematic mutagenesis of the E. coli (MG1655) genome J Bacteriol 2004, 186:4921-4930

Phenotypes and Validation (curated)

We have no manually annotated phenotypes for this target. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please contact us.

Annotated validation

No validation data for this target

Associated compounds / Druggability

Known modulators for this target

No chemical compounds associated to this gene

Predicted associations

By orthology with druggable targets
Species Known druggable target Linked compounds Reference
Bacillus anthracis Nicotinate-nucleotide adenylyltransferase Compounds References
Escherichia coli nicotinic acid mononucleotide adenylyltransferase, NAD(P)-dependent Compounds References
Staphylococcus aureus (strain N315) Probable nicotinate-nucleotide adenylyltransferase Compounds References
By sequence similarity to non orthologous druggable targets
No additional associated druggable targets
Obtained from network model

Ranking Plot

Putative Drugs List

Compound Raw Global Species
0.0345 0.3361 1
0.0585 0.2701 1
0.0557 0.5833 1
0.0284 0.6466 1
0.0296 0.339 1
0.0303 0.2594 0.3225
0.0591 0.3446 0.4767
0.0278 0.384 0.5
0.0287 0.3993 1
0.0345 0.4144 0.5
0.0345 0.6946 0.5
0.0619 0.4104 1
0.0989 0.275 1
0.0345 0.4845 1
0.0564 0.7906 1
0.0345 0.3397 0.5
0.0327 0.4047 1
0.087 0.7139 1
0.0229 0.3993 1
0.0582 0.6774 1
0.0302 0.3852 1
0.0305 0.2646 0.328
0.0573 0.3546 0.5
0.028 0.4621 0
0.0286 0.4554 0.5
0.0844 0.3901 1
0.0978 0.4156 1
0.0342 0.2912 1
0.0345 0.4079 0.4934
0.0319 0.8019 1
0.0279 0.3267 1
0.0279 0.2707 0.2707
0.0345 0.3491 1
0.0297 0.3423 0.8744
0.0345 0.4084 1
0.0287 0.4014 1
0.0153 0.2964 1
0.0278 0.7464 1
0.0271 0.3096 1
0.0345 0.2702 1
0.0345 0.4309 0.5
0.0285 0.2873 1
0.0317 0.3712 1
0.0331 0.3882 1
0.0327 0.3554 1
0.0345 0.402 1
0.0913 0.3517 1
0.0317 0.3717 1
0.0345 0.401 1
0.0306 0.3989 0.8509
0.0343 0.3075 1
0.026 0.279 1
0.0279 0.3963 0
0.0316 0.3642 1
0.0598 0.6916 1
0.0345 0.3275 1
0.0911 0.4147 1
0.0578 0.4052 1
0.0345 0.384 1
0.0278 0.4106 1
0.0345 0.41 0.5
0.0989 0.9614 1
0.0345 0.4074 1
0.0313 0.8894 1
0.0345 0.6936 1
0.0315 0.4985 1
0.0564 0.6628 1
0.0345 0.6926 1
0.0582 0.2541 0.9047
0.0624 0.4594 1
0.0281 0.2835 0.5
0.0283 0.408 1
0.0655 0.695 1
0.0345 0.4322 0.5
0.0558 0.2775 1
0.0989 0.3459 1
0.0567 0.6265 1
0.0345 0.3913 1
0.0936 0.2614 1
0.0345 0.2643 1
0.0864 0.5223 1
0.0316 0.3642 1
0.0286 0.7452 0.5
0.0302 0.4452 1
0.0682 0.3875 1
0.0345 0.6463 0.5
0.0277 0.6928 0.5
0.0297 0.9508 0.5
0.0862 0.524 1
0.0335 0.3428 1
0.0281 0.9734 1
0.0293 0.6676 1
0.0285 0.2742 1
0.0345 0.4709 1
0.0345 0.3481 0.5
0.0303 0.3709 1
0.0928 0.2624 1
0.0552 0.3123 1
0.0323 0.3258 1
0.0293 0.594 1
0.0279 0.3353 1
0.0297 0.3607 0.5
0.089 0.7031 0.8797
0.0637 0.2793 1
0.0264 0.3821 1
0.0601 0.3103 0.3839
0.0309 0.5463 0.5
0.0287 0.2957 1
0.0291 0.9226 1
0.1268 0.5524 1
0.0345 0.4075 1
0.0345 0.4037 0.5
0.0602 0.3573 1
0.0288 0.2798 1
0.0279 0.3413 1
0.0648 0.408 1
0.0295 0.5047 1
0.0312 0.4075 0.4934
0.0283 0.3475 1
0.0311 0.3282 1
0.0958 0.4793 1
0.0331 0.3139 1
0.0925 0.4149 1
0.0587 0.7296 1
0.0307 0.3904 1
0.0345 0.6069 1
0.0241 0.3302 1
0.0656 0.5058 1
0.0266 0.3019 1
0.0236 0.4061 1
0.0895 0.3075 1
0.1433 0.5829 1
0.0345 0.3491 1
0.0926 0.419 1
0.0345 0.4445 1
0.0279 0.3412 1
0.0613 0.2555 1
0.0287 0.2849 1
0.0287 0.2604 0.4216
0.0345 0.4002 0.5
0.0276 0.8166 0.5
0.0282 0.4872 1
0.0345 0.409 1
0.0345 0.3993 1
0.0281 0.2641 1
0.0937 0.7074 1
0.0901 0.4051 1
0.0337 0.8415 0.5
0.0345 0.2559 1
0.0336 0.3488 1
0.0323 0.3446 1
0.0244 0.3001 1
0.0578 0.3569 0.4474
0.0319 0.5011 1
0.0342 0.35 1
0.0345 0.9257 1
0.031 0.9324 1
0.0335 0.4058 1
0.0561 0.2614 1
0.0303 0.3844 1
0.033 0.4062 1
0.0276 0.3049 1
0.0279 0.4039 0.5
0.0955 0.52 1
0.0285 0.6895 1
0.0902 0.3744 1
0.0914 0.7152 1
0.0938 0.4042 1
0.0335 0.3461 1
0.0282 0.401 0.8208
0.0523 0.2726 1
0.0926 0.419 1
0.0847 0.6886 1
0.057 0.2596 1
0.0307 0.3455 1
0.0995 0.9787 1
0.0293 0.3831 1
0.0611 0.3502 1
0.0595 0.2908 0.4295
0.0289 0.29 1
0.0667 0.7162 0.5
0.0634 0.3481 1
0.0576 0.3604 0.5624
0.0301 0.3388 0.4286
0.0327 0.4081 1
0.0285 0.4078 1
0.0345 0.7402 0.5
0.0241 0.3302 1
0.0345 0.3658 1
0.0226 0.3211 1
0.0345 0.4075 1
0.0345 0.9098 1
0.0553 0.6989 1
0.0917 0.6382 1
0.0989 0.3459 1
0.0283 0.9734 1
0.028 0.3987 1
0.0905 0.5499 1
0.0302 0.3464 0.5
0.0307 0.4388 1
0.0926 0.4045 1
0.0281 0.3708 1
0.0345 0.3467 1
0.0293 0.3428 1
0.0315 0.4157 1
0.0276 0.3033 1
0.034 0.4846 0.5
0.09 0.3521 1
0.033 0.394 0.712
0.0335 0.2505 1
0.0345 0.3401 1
0.0345 0.4088 1
0.0594 0.3134 0.6508
0.0538 0.3915 1
0.0345 0.3467 1
0.0345 0.6868 1
0.0611 0.2573 1
0.0308 0.3955 1
0.0243 0.3995 0.5
0.0281 0.6919 1
0.0911 0.5303 1
0.0345 0.3893 1
0.0284 0.6928 1
0.0334 0.4081 1
0.0651 0.3457 1
0.028 0.8162 0.5
0.0611 0.3502 1
0.0602 0.3403 0.4397
0.0897 0.6937 1
0.0643 0.4584 1
0.0282 0.3659 0.5
0.0345 0.387 0.5
0.0329 0.5672 1
0.0286 0.3281 1
0.0913 0.3517 1
0.0607 0.3491 1
0.0345 0.9689 1
0.0345 0.4074 1
0.0289 0.289 1
0.0345 0.4081 1
0.0345 0.3831 1
0.0679 0.2835 0.5
0.0261 0.6491 1
0.0283 0.5033 0.5
0.0288 0.4103 1
0.0648 0.408 1
0.0345 0.9426 1
0.0332 0.3471 1
0.0182 0.4482 1
0.0345 0.3763 1
0.0345 0.3831 1
0.0598 0.2901 0.3713
0.0315 0.3391 1
0.0601 0.316 0.7389
0.0153 0.2971 1
0.0318 0.5121 1
0.0575 0.4262 0.5351
0.0284 0.45 0.7838
0.0337 0.7944 1
0.0292 0.3424 1
0.0345 0.402 1
0.0345 0.3471 1
0.0988 0.5216 1
0.0283 0.3346 1
0.028 0.4589 0.5
0.0283 0.633 1
0.0309 0.9907 1
0.0311 0.4211 1
0.0405 0.4172 1
0.0303 0.6032 0.5
0.0572 0.8223 1
0.0284 0.2794 1
0.0345 0.3467 1
0.0324 0.3894 1
0.0311 0.3625 1
0.0345 0.3437 1
0.0592 0.4628 0.9062
0.057 0.2596 1
0.0345 0.6941 1
0.0345 0.9426 1
0.128 0.4145 1
0.0328 0.3993 0.7097
0.0345 0.4532 1
0.034 0.4034 1
0.0345 0.3993 1
0.0286 0.693 1
0.0306 0.273 1
0.0249 0.2935 0.5
0.0327 0.6126 1
0.0225 0.3913 1
0.0319 0.6694 1
0.0319 0.3405 0
0.0345 0.4077 1
0.0288 0.3394 1
0.028 0.3459 1
0.033 0.4062 1
0.0615 0.6994 1
0.0574 0.6915 1
0.132 0.4665 1
0.0277 0.4401 0.7639
0.0627 0.424 0.5
0.0335 0.3987 1
0.0345 0.6895 1
0.1433 0.5829 1
0.0897 0.6937 1
0.028 0.5078 1
0.057 0.2596 1
0.0345 0.4198 1
0.0319 0.3719 1
0.0302 0.3464 0.5
0.0593 0.3345 0.482
0.0345 0.9216 0.5
0.0286 0.4554 0.5
0.0345 0.4222 1
0.0581 0.4057 0.5245
0.0914 0.4182 1
0.0327 0.6126 1
0.0282 0.8369 1
0.0574 0.3452 1
0.029 0.6946 0.5
0.0664 0.5865 1
0.0311 0.3625 1
0.0933 0.2622 1
0.0345 0.339 1
0.0307 0.3963 0.8525
0.0282 0.6068 0.9928
0.0292 0.3339 0
0.0284 0.45 0.7838
0.0153 0.2964 1
0.0304 0.3613 1
0.0289 0.5026 0.8104
0.1127 0.4106 1
0.0345 0.6937 1
0.0284 0.3486 1
0.0345 0.6946 1
0.0345 0.3763 1
0.0345 0.3844 1
0.0843 0.3891 1
0.0317 0.3383 1
0.0325 0.3999 1
0.0276 0.8176 0.5
0.0289 0.3649 1
0.028 0.6936 1
0.0311 0.6946 0.5
0.0328 0.3386 1
0.0641 0.3888 1
0.0296 0.3472 1
0.0656 0.5957 1
0.0975 0.7135 1
0.0345 0.3914 1
0.0574 0.9438 1
0.0308 0.309 1
0.0277 0.6119 1
0.0611 0.3502 1
0.031 0.3575 0.5
0.0989 0.275 1
0.0276 0.4078 1
0.0286 0.3453 1
0.0345 0.383 1
0.0589 0.9189 1
0.0345 0.4059 1
0.0292 0.4091 0.5
0.0276 0.3417 0.9503
0.0966 0.3062 1
0.0325 0.4069 1
0.0345 0.2702 1
0.0345 0.4325 0.5
0.0294 0.2952 1
0.0333 0.4433 1
0.0279 0.3201 1
0.0309 0.3709 1
0.0293 0.3969 1
0.0277 0.3251 1
0.0256 0.3383 1
0.0335 0.3327 1
0.0891 0.2844 1
0.024 0.3758 1
0.058 0.4234 1
0.029 0.3466 1
0.0284 0.2794 1
0.0665 0.8128 1
0.0345 0.5555 1
0.0281 0.9734 1
0.0345 0.3433 1
0.0287 0.2604 0.4216
0.0642 0.3592 1
0.0581 0.4057 0.5245
0.0345 0.3481 0.5
0.0299 0.3318 1
0.029 0.3632 1
0.0613 0.2555 1
0.0579 0.3402 0.439
0.0313 0.9736 1
0.0984 0.4422 1
0.0204 0.3202 1
0.0293 0.6946 0.5
0.0279 0.3903 0.6188
0.0889 0.524 1
0.0279 0.388 1
0.0285 0.6895 1
0.0172 0.2685 1
0.0296 0.3038 1
0.0316 0.3642 1
0.034 0.3567 1
0.0284 0.3419 1
0.0345 0.6131 1
0.0288 0.6951 1
0.0345 0.2643 1
0.0605 0.423 1
0.0308 0.3374 1
0.0566 0.6851 1
0.0609 0.6166 0.5
0.091 0.5477 1
0.0641 0.6232 1
0.0345 0.3413 1
0.0276 0.9734 1
0.0345 0.4084 0.5
0.0309 0.3399 1
0.0345 0.3413 1
0.0287 0.2849 1
0.0306 0.4065 1
0.0544 0.3477 1
0.0333 0.3319 1
0.0284 0.5488 1
0.0582 0.2541 0.9047
0.0284 0.3297 1
0.0295 0.6906 1
0.0231 0.6923 1
0.0283 0.9734 1
0.0246 0.6193 1
0.0279 0.6915 0.5
0.0345 0.4105 1
0.0924 0.7249 1
0.0289 0.29 1
0.0874 0.3079 1
0.028 0.7686 1
0.0874 0.3079 1
0.0295 0.3965 1
0.057 0.4034 0.5
0.0624 0.4594 1
0.0345 0.3963 1
0.0345 0.3094 0.5
0.0293 0.3578 1
0.056 0.6923 1
0.0345 0.4037 1
0.0334 0.3276 1
0.0295 0.3383 0.5022
0.0575 0.4149 1
0.064 0.4676 1
0.1134 0.6759 1
0.0345 0.3459 1
0.0323 0.3453 1
0.0345 0.3906 1
0.0291 0.3398 1
0.0879 0.6878 1
0.1181 0.4603 1
0.0231 0.6391 0.5
0.1279 0.3492 1
0.089 0.4095 1
0.0656 0.6892 1
0.0689 0.2508 1
0.0345 0.9249 0.5
0.0299 0.3956 1
0.0307 0.378 1
0.0303 0.4883 0.5
0.0345 0.4064 0.5
0.0345 0.3418 0.5
0.0334 0.3713 1
0.0345 0.3476 1
0.0281 0.5012 1
0.0881 0.685 1
0.0278 0.3246 1
0.0281 0.3459 1
0.0311 0.9759 1
0.033 0.3621 1
0.0289 0.5504 1
0.0667 0.7162 0.5
0.0283 0.633 1
0.0345 0.4088 0.5
0.0345 0.4048 1
0.0291 0.2886 0.5
0.0345 0.4084 1
0.089 0.5461 0.875
0.0902 0.5383 1
0.0294 0.4079 1
0.0312 0.4 1
0.0279 0.9975 0.5
0.0648 0.3763 1
0.0306 0.4894 0.5
0.0335 0.6928 1
0.0636 0.2748 0.7779
0.0278 0.3638 1
0.0215 0.2614 1
0.0345 0.4079 1
0.0244 0.3993 1
0.0337 0.789 0.5
0.0267 0.284 1
0.0277 0.3473 1
0.0283 0.408 1
0.0345 0.3467 1
0.0345 0.4092 1
0.0345 0.9837 0.5
0.0342 0.2912 1
0.0317 0.3717 1
0.0654 0.3479 1
0.0288 0.3396 1
0.0269 0.3319 1
0.0967 0.2645 1
0.0345 0.3488 1
0.0442 0.2595 1
0.0663 0.3466 1
0.094 0.4107 1
0.0345 0.3486 1
0.0345 0.9358 0.5
0.0339 0.3812 1
0.0876 0.5295 1
0.0296 0.3386 1
0.0282 0.401 0.8208
0.0326 0.3419 1
0.0319 0.6694 1
0.0289 0.3296 0.5
0.0895 0.5267 1
0.0584 0.3107 0.3913
0.0304 0.6923 1
0.0291 0.3654 1
0.0282 0.667 0.6604
0.0345 0.3454 1
0.0324 0.406 1
0.0613 0.2555 1
0.0624 0.4594 1
0.0933 0.2546 1
0.0915 0.7086 1
0.0578 0.3558 0.4468
0.0302 0.3629 1
0.0677 0.3852 1
0.0276 0.3359 1
0.1205 0.4091 1
0.0939 0.7091 1
0.0314 0.3382 1
0.0598 0.4261 1
0.0345 0.3947 1
0.0846 0.3473 1
0.0299 0.2945 1
0.0917 0.5523 1
0.0658 0.3383 1
0.0278 0.3098 1
0.025 0.6646 1
0.0917 0.6382 1
0.0205 0.2555 1
0.0611 0.3502 1
0.0345 0.4262 1
0.0989 0.275 1
0.0619 0.3406 1
0.0305 0.3993 1
0.0295 0.3447 1
0.026 0.279 1
0.0337 0.847 0.5
0.0345 0.427 1
0.0345 0.3884 1
0.0345 0.4031 1
0.0317 0.3717 1
0.0321 0.3949 1
0.0345 0.3884 1
0.033 0.2579 1
0.0297 0.3423 0.8744
0.0306 0.3653 1
0.0309 0.3399 1
0.0281 0.5906 1
0.0345 0.2809 0.5
0.032 0.3199 1
0.1433 0.5829 1
0.0644 0.6896 1
0.0576 0.3618 1
0.0332 0.7939 1
0.0345 0.3486 1
0.0321 0.3949 1
0.0277 0.2817 0.5844
0.0531 0.2692 0.456
0.0647 0.351 1
0.0345 0.4081 1
0.0285 0.4993 0
0.0316 0.3642 1
0.0345 0.4048 0.5
0.0564 0.4242 0.5305
0.0634 0.468 1
0.0325 0.3685 1
0.0279 0.3592 1
0.0204 0.3796 1
0.0286 0.3397 1
0.0302 0.363 1
0.0289 0.372 1
0.1458 0.59 1
0.0345 0.3993 0.5
0.0279 0.3889 0.5
0.0871 0.703 1
0.0276 0.7532 0.5
0.0294 0.358 0.6069
0.0345 0.4081 1
0.0303 0.3945 1
0.0345 0.6951 1
0.0345 0.3893 1
0.03 0.4088 1
0.0345 0.6904 0.5
0.0239 0.3175 1
0.0345 0.9241 0.5
0.0558 0.4564 0.5835
0.0345 0.4198 1
0.0345 0.4088 1
0.0315 0.3946 1
0.0345 0.4062 1
0.089 0.4095 1
0.0911 0.4147 1
0.0345 0.3418 1
0.0296 0.3965 1
0.033 0.394 0.712
0.0652 0.349 1
0.0345 0.6771 1
0.0345 0.4135 1
0.0217 0.3481 1
0.0287 0.2957 1
0.0278 0.4019 0.8212
0.0274 0.3337 0.5
0.0287 0.3467 1
0.0345 0.3486 1
0.0345 0.6036 1
0.0321 0.3156 0.448
0.0287 0.6323 0.5
0.0309 0.4951 0.5
0.0647 0.351 1
0.057 0.2596 1
0.0345 0.404 1
0.0287 0.3006 1
0.0277 0.2562 0.5
0.027 0.9 1
0.0308 0.3982 1
0.027 0.695 0.5
0.0342 0.2912 1
0.0284 0.5153 1
0.0288 0.3394 1
0.0345 0.3394 1
0.0345 0.4429 0.5
0.0276 0.4291 1
0.0318 0.3155 0.5
0.0311 0.3897 1
0.0613 0.377 0.6461
0.0331 0.8088 1
0.0288 0.3417 1
0.0538 0.3915 1
0.0333 0.3883 1
0.0286 0.4554 0.5
0.057 0.2596 1
0.0278 0.2912 0.5
0.0345 0.3492 1
0.0345 0.3486 1
0.0937 0.7074 1
0.0897 0.5574 1
0.0297 0.3462 0.5
0.0608 0.2599 1
0.0292 0.5945 1
0.0681 0.2814 1
0.0915 0.5574 1
0.0663 0.4089 1
0.0268 0.3349 0.4994
0.0283 0.2899 1
0.0281 0.3467 1
0.0346 0.3666 1
0.0278 0.3149 1
0.0639 0.5848 1
0.0283 0.408 1
0.0615 0.4411 1
0.0345 0.921 1
0.0308 0.3853 1
0.0331 0.3469 1
0.0281 0.2835 0.5
0.0617 0.3382 1
0.026 0.2683 1
0.0325 0.6928 0.5
0.0333 0.4228 0.5
0.0345 0.344 0.4133
0.0345 0.3454 1
0.0557 0.5634 0.5
0.0345 0.2559 1
0.0283 0.3333 1
0.0903 0.7194 1
0.0283 0.3656 1
0.0278 0.337 0.5
0.0324 0.3894 1
0.0277 0.3323 1
0.0608 0.4397 1
0.0345 0.3456 1
0.0295 0.5047 1
0.031 0.3406 1
0.0665 0.6146 1
0.0285 0.2664 1
0.0331 0.4002 1
0.0329 0.4453 0.5
0.0345 0.4325 0.5
0.0906 0.5396 1
0.0256 0.6115 1
0.0345 0.3763 1
0.0336 0.6072 1
0.028 0.3987 1
0.0581 0.2916 0.4055
0.0276 0.9742 1
0.0332 0.7939 1
0.0288 0.3471 1
0.0955 0.2578 1
0.0951 0.4182 1
0.0345 0.344 0.4133
0.0341 0.4651 0.5
0.0278 0.4106 1
0.0345 0.406 1
0.0907 0.7283 0.9283
0.0896 0.7098 1
0.0345 0.3796 1
0.0299 0.4055 1
0.0281 0.5012 1
0.0299 0.4055 1
0.0277 0.985 0.5
0.0332 0.9585 1
0.0295 0.2912 0.5051
0.0279 0.405 1
0.0624 0.4594 1
0.0967 0.2645 1
0.0288 0.3203 1
0.0277 0.7883 1
0.1169 0.2775 1
0.0278 0.3665 0.5
0.0849 0.7346 0.5
0.0286 0.6037 1
0.0336 0.3753 1
0.0345 0.3463 1

Assayability

Assay information

No assay information for this target.

Reagent availability

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Gene identifier ML1454c (Mycobacterium leprae), PROBABLE NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE NADD (DEAMIDO-NAD(+) PYROPHOSPHORYLASE) (DEAMIDO-NAD(+) DIPHOSPHORYLASE) (NIC
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