Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | ceramide glucosyltransferase | 0.1408 | 0.961 | 1 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.1408 | 0.961 | 1 |
Onchocerca volvulus | Ceramide glucosyltransferase homolog | 0.1408 | 0.961 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.1302 | 0.8798 | 0.9155 |
Schistosoma mansoni | alpha-glucosidase | 0.1302 | 0.8798 | 0.9155 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.1027 | 0.6677 | 0.6948 |
Echinococcus granulosus | non lysosomal glucosylceramidase | 0.1027 | 0.6677 | 0.6339 |
Schistosoma mansoni | alpha glucosidase | 0.0281 | 0.0925 | 0.0962 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0495 | 0.2575 | 0.4521 |
Onchocerca volvulus | 0.0875 | 0.5505 | 0.4164 | |
Loa Loa (eye worm) | ceramide glucosyltransferase | 0.1408 | 0.961 | 0.957 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0281 | 0.0925 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0754 | 0.4575 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0281 | 0.0925 | 0.5 |
Echinococcus multilocularis | bile acid beta glucosidase | 0.1027 | 0.6677 | 0.6339 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0754 | 0.4575 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0281 | 0.0925 | 0.5 |
Brugia malayi | Ceramide glucosyltransferase | 0.1408 | 0.961 | 0.957 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0495 | 0.2575 | 0.4521 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0281 | 0.0925 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0522 | 0.2781 | 0.5084 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0754 | 0.4575 | 1 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0754 | 0.4575 | 0.4022 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0495 | 0.2575 | 0.4521 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0754 | 0.4575 | 1 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0281 | 0.0925 | 0.5 |
Echinococcus granulosus | ceramide glucosyltransferase | 0.1408 | 0.961 | 0.957 |
Trypanosoma brucei | glucosidase, putative | 0.0281 | 0.0925 | 0.5 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0754 | 0.4575 | 0.4022 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0495 | 0.2575 | 0.4521 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0281 | 0.0925 | 0.5 |
Echinococcus multilocularis | non lysosomal glucosylceramidase | 0.1027 | 0.6677 | 0.6339 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0522 | 0.2781 | 0.5084 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0754 | 0.4575 | 1 |
Echinococcus multilocularis | ceramide glucosyltransferase | 0.1408 | 0.961 | 0.957 |
Loa Loa (eye worm) | hypothetical protein | 0.0693 | 0.4104 | 0.3503 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0754 | 0.4575 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0495 | 0.2575 | 0.4521 |
Giardia lamblia | Ceramide glucosyltransferase | 0.0638 | 0.3678 | 0.5 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.1027 | 0.6677 | 0.6948 |
Echinococcus granulosus | bile acid beta glucosidase | 0.1027 | 0.6677 | 0.6339 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0495 | 0.2575 | 0.4521 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0495 | 0.2575 | 0.4521 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.