Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0992 | 1 | 0.5 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0218 | 0.0329 |
Echinococcus granulosus | mucolipin 3 | 0.0063 | 0.0237 | 0.0177 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0218 | 0.0329 |
Brugia malayi | Coelomocyte uptake defective protein 5 | 0.0063 | 0.0237 | 0.0019 |
Trypanosoma brucei | Prostaglandin E synthase | 0.0992 | 1 | 0.5 |
Echinococcus multilocularis | intestinal type alkaline phosphatase | 0.0163 | 0.1291 | 1 |
Echinococcus multilocularis | alkaline phosphatase | 0.0163 | 0.1291 | 1 |
Schistosoma mansoni | mucolipin | 0.0063 | 0.0237 | 0.0499 |
Echinococcus multilocularis | intestinal type alkaline phosphatase 1 | 0.0163 | 0.1291 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0218 | 0.0329 |
Loa Loa (eye worm) | mucolipin 1 | 0.0063 | 0.0237 | 0.0019 |
Echinococcus granulosus | alkaline phosphatase | 0.0163 | 0.1291 | 1 |
Trypanosoma cruzi | glutathione-S-transferase/glutaredoxin, putative | 0.0992 | 1 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0218 | 0.0329 |
Trypanosoma cruzi | glutathione-S-transferase/glutaredoxin, putative | 0.0992 | 1 | 0.5 |
Schistosoma mansoni | alkaline phosphatase | 0.0163 | 0.1291 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0085 | 0.0466 | 0.2567 |
Echinococcus granulosus | intestinal type alkaline phosphatase | 0.0163 | 0.1291 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0218 | 0.0329 |
Echinococcus multilocularis | alkaline phosphatase, intestinal, gene 2 | 0.0163 | 0.1291 | 1 |
Schistosoma mansoni | alkaline phosphatase | 0.0163 | 0.1291 | 1 |
Echinococcus granulosus | intestinal type alkaline phosphatase 1 | 0.0163 | 0.1291 | 1 |
Echinococcus granulosus | alkaline phosphatase intestinal gene 2 | 0.0163 | 0.1291 | 1 |
Echinococcus multilocularis | mucolipin 3 | 0.0063 | 0.0237 | 0.0177 |
Loa Loa (eye worm) | hypothetical protein | 0.0992 | 1 | 1 |
Leishmania major | glutathione-S-transferase/glutaredoxin, putative | 0.0992 | 1 | 0.5 |
Toxoplasma gondii | prostaglandin-E synthase | 0.0992 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.