Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Wolbachia endosymbiont of Brugia malayi | major facilitator superfamily permease | 0.0106 | 1 | 0.5 |
Trichomonas vaginalis | Regulatory protein uhpC, putative | 0.0106 | 1 | 0.5 |
Trichomonas vaginalis | glucarate, hexuronate transporter, putative | 0.0106 | 1 | 0.5 |
Trichomonas vaginalis | Hexuronate transporter, putative | 0.0106 | 1 | 0.5 |
Giardia lamblia | Sugar transport family protein | 0.0106 | 1 | 0.5 |
Onchocerca volvulus | Phospholipase A2 homolog | 0.0046 | 0 | 0.5 |
Trichomonas vaginalis | glucarate, hexuronate transporter, putative | 0.0106 | 1 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0106 | 1 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0106 | 1 | 0.5 |
Trichomonas vaginalis | Regulatory protein uhpC, putative | 0.0106 | 1 | 0.5 |
Onchocerca volvulus | Phospholipase A2 homolog | 0.0046 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0106 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0106 | 1 | 0.5 |
Trichomonas vaginalis | glucose-6-phosphate translocase, putative | 0.0106 | 1 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0106 | 1 | 0.5 |
Chlamydia trachomatis | hexose phosphate transporter | 0.0106 | 1 | 0.5 |
Trichomonas vaginalis | transport proetin, putative | 0.0106 | 1 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0106 | 1 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0106 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable conserved integral membrane protein | 0.0106 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.