TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 429.528 | Formula: C24H32FN3O3
H donors: 2 H acceptors: 1 LogP: 3.51 Rotable bonds: 9
Rule of 5 violations (Lipinski): 1
SMILES: FCCOc1ccc(cc1)N1CCN(CC1)CCNC[C@H]1CCc2c(O1)cc(cc2)O
InChi: 1S/C24H32FN3O3/c25-9-16-30-22-7-3-20(4-8-22)28-14-12-27(13-15-28)11-10-26-18-23-6-2-19-1-5-21(29)17-24(19)31-23/h1,3-5,7-8,17,23,26,29H,2,6,9-16,18H2/t23-/m1/s1
InChiKey: MSHUBKLFRWFTKI-HSZRJFAPSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Entamoeba histolytica	tyrosine kinase, putative	0.0061	0.3192	0.3216
Loa Loa (eye worm)	TK protein kinase	0.0103	0.9925	1
Entamoeba histolytica	hypothetical protein, conserved	0.0061	0.3192	0.3216
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.0103	0.9925	1
Loa Loa (eye worm)	hypothetical protein	0.0061	0.3192	0.106
Loa Loa (eye worm)	TK/EPH protein kinase	0.0061	0.3192	0.106
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0061	0.3192	0.3216
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Loa Loa (eye worm)	hypothetical protein	0.0061	0.3192	0.106
Schistosoma mansoni	protein kinase	0.0062	0.3267	0.116
Entamoeba histolytica	protein kinase, putative	0.0061	0.3192	0.3216
Trichomonas vaginalis	protein tyrosine kinase, putative	0.0061	0.3192	1
Loa Loa (eye worm)	hypothetical protein	0.0061	0.3192	0.106
Brugia malayi	protein-tyrosine kinase	0.0103	0.9925	1
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0061	0.3192	0.106
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0061	0.3192	0.106
Loa Loa (eye worm)	TKL/MLK/TAK1 protein kinase	0.0061	0.3192	0.106
Entamoeba histolytica	protein kinase, putative	0.0061	0.3192	0.3216
Brugia malayi	Protein kinase domain containing protein	0.0061	0.3192	0.106
Loa Loa (eye worm)	TK/ALK protein kinase	0.0061	0.3192	0.106
Trichomonas vaginalis	conserved hypothetical protein	0.0061	0.3192	1
Onchocerca volvulus		0.0103	0.9925	1
Schistosoma mansoni	protein kinase	0.0061	0.3192	0.106
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0103	0.9925	0.9901
Entamoeba histolytica	protein kinase, putative	0.0061	0.3192	0.3216
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0061	0.3192	0.106
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Entamoeba histolytica	protein kinase domain containing protein	0.0061	0.3192	0.3216
Entamoeba histolytica	hypothetical protein	0.0061	0.3192	0.3216
Entamoeba histolytica	protein kinase, putative	0.0061	0.3192	0.3216
Schistosoma mansoni	tyrosine kinase	0.0061	0.3192	0.106
Brugia malayi	Protein kinase domain containing protein	0.0061	0.3192	0.106
Brugia malayi	Protein kinase domain containing protein	0.0061	0.3192	0.106
Echinococcus multilocularis	protein KINase family member (kin 25)	0.0061	0.3192	0.106
Entamoeba histolytica	protein kinase domain containing protein	0.0061	0.3192	0.3216
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0061	0.3192	0.106
Entamoeba histolytica	tyrosine kinase, putative	0.0061	0.3192	0.3216
Plasmodium falciparum	protein kinase, putative	0.0061	0.3192	0.9139
Brugia malayi	Tyrosine-protein kinase abl-1	0.0103	0.9925	1
Brugia malayi	hypothetical protein	0.0061	0.3192	0.106
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0061	0.3192	0.106
Brugia malayi	hypothetical protein	0.0103	0.9925	1
Schistosoma mansoni	tyrosine kinase	0.0061	0.3192	0.106
Brugia malayi	Protein kinase domain containing protein	0.0061	0.3192	0.106
Schistosoma mansoni	protein tyrosine kinase	0.0061	0.3192	0.106
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Schistosoma mansoni	protein kinase	0.0061	0.3192	0.106
Trichomonas vaginalis	conserved hypothetical protein	0.0061	0.3192	1
Loa Loa (eye worm)	hypothetical protein	0.0061	0.3192	0.106
Entamoeba histolytica	tyrosine kinase, putative	0.0061	0.3192	0.3216
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0061	0.3192	0.3216
Loa Loa (eye worm)	TK protein kinase	0.0061	0.3192	0.106
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Schistosoma mansoni	tyrosine kinase	0.0103	0.9925	1
Loa Loa (eye worm)	hypothetical protein	0.0061	0.3192	0.106
Plasmodium vivax	protein kinase, putative	0.0061	0.3192	1
Loa Loa (eye worm)	TK protein kinase	0.0061	0.3192	0.106
Echinococcus granulosus	insulin receptor	0.0061	0.3192	0.105
Loa Loa (eye worm)	hypothetical protein	0.0061	0.3192	0.106
Entamoeba histolytica	protein kinase, putative	0.0061	0.3192	0.3216
Schistosoma mansoni	serine/threonine protein kinase	0.0061	0.3192	0.106
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Schistosoma mansoni	tyrosine kinase	0.0061	0.3192	0.106
Brugia malayi	integrin-linked kinase	0.0061	0.3192	0.106
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Loa Loa (eye worm)	TK/ACK protein kinase	0.0061	0.3192	0.106
Echinococcus multilocularis	tyrosine protein kinase csk	0.0061	0.3192	0.106
Echinococcus granulosus	activated cdc42 kinase 1	0.0061	0.3192	0.105
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Trichomonas vaginalis	TK family protein kinase	0.0061	0.3192	1
Entamoeba histolytica	protein kinase domain containing protein	0.0061	0.3192	0.3216
Brugia malayi	SH2 domain containing protein	0.0103	0.9925	1
Brugia malayi	Protein kinase domain containing protein	0.0103	0.9925	1
Giardia lamblia	Kinase	0.0061	0.3192	1
Entamoeba histolytica	protein kinase with ankyrin repeats, putative	0.0061	0.3192	0.3216
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0061	0.3192	1
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Entamoeba histolytica	hypothetical protein	0.0061	0.3192	0.3216
Entamoeba histolytica	protein kinase domain containing protein	0.0061	0.3192	0.3216
Entamoeba histolytica	tyrosine kinase, putative	0.0061	0.3192	0.3216
Schistosoma mansoni	tyrosine kinase	0.0061	0.3192	0.106
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0061	0.3192	0.106
Entamoeba histolytica	tyrosine kinase, putative	0.0061	0.3192	0.3216
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0061	0.3192	0.3216
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0061	0.3192	0.3216
Toxoplasma gondii	protein kinase	0.0061	0.3192	0.9139
Schistosoma mansoni	protein kinase	0.0061	0.3192	0.106
Toxoplasma gondii	STE kinase	0.0061	0.3192	0.9139
Brugia malayi	Raf kinase	0.0061	0.3192	0.106
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0061	0.3192	0.9139
Schistosoma mansoni	protein kinase	0.0061	0.3192	0.106
Entamoeba histolytica	protein kinase domain containing protein	0.0061	0.3192	0.3216
Onchocerca volvulus		0.0103	0.9925	1
Loa Loa (eye worm)	hypothetical protein	0.0061	0.3192	0.106
Echinococcus granulosus	tyrosine protein kinase csk	0.0061	0.3192	0.105
Toxoplasma gondii	calcium dependent protein kinase CDPK8	0.0062	0.3267	1
Schistosoma mansoni	tyrosine kinase	0.0061	0.3192	0.106
Schistosoma mansoni	tyrosine kinase	0.0061	0.3192	0.106
Echinococcus multilocularis	integrin linked protein kinase	0.0061	0.3192	0.106
Schistosoma mansoni	tyrosine kinase	0.0061	0.3192	0.106
Brugia malayi	Protein kinase domain containing protein	0.0061	0.3192	0.106
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0061	0.3192	0.9139
Entamoeba histolytica	leucine-rich repeat domain-containing protein	0.0061	0.3192	0.3216
Schistosoma mansoni	tyrosine kinase	0.0103	0.9925	1
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0061	0.3192	0.106
Trichomonas vaginalis	AGC family protein kinase	0.0061	0.3192	1
Echinococcus granulosus	tyrosine kinase	0.0061	0.3192	0.105
Loa Loa (eye worm)	hypothetical protein	0.0061	0.3192	0.106
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Brugia malayi	Protein kinase domain containing protein	0.0061	0.3192	0.106
Brugia malayi	SRC-1	0.0103	0.9925	1
Echinococcus granulosus	c src tyrosine kinase	0.0103	0.9925	0.9901
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.0077	0.5721	0.4419
Entamoeba histolytica	protein kinase, putative	0.0061	0.3192	0.3216
Schistosoma mansoni	tyrosine kinase	0.0061	0.3192	0.106
Entamoeba histolytica	protein kinase, putative	0.0061	0.3192	0.3216
Loa Loa (eye worm)	TK/CSK protein kinase	0.0061	0.3192	0.106
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0061	0.3192	0.105
Brugia malayi	proto-oncogene tyrosine-protein kinase FER	0.0061	0.3192	0.106
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0061	0.3192	0.106
Loa Loa (eye worm)	TK/FAK protein kinase	0.0061	0.3192	0.106
Schistosoma mansoni	tyrosine kinase	0.0061	0.3192	0.106
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Entamoeba histolytica	tyrosin kinase, putative	0.0061	0.3192	0.3216
Entamoeba histolytica	protein kinase domain containing protein	0.0061	0.3192	0.3216
Loa Loa (eye worm)	hypothetical protein	0.0061	0.3192	0.106
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0061	0.3192	0.106
Entamoeba histolytica	hypothetical protein	0.0061	0.3192	0.3216
Schistosoma mansoni	protein kinase	0.0061	0.3192	0.106
Plasmodium falciparum	tyrosine kinase-like protein	0.0061	0.3192	0.9139
Entamoeba histolytica	protein kinase, putative	0.0061	0.3192	0.3216
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Echinococcus multilocularis	c src tyrosine kinase	0.0103	0.9925	1
Echinococcus granulosus	atrial natriuretic peptide receptor 1	0.0061	0.3192	0.105
Brugia malayi	Protein kinase domain containing protein	0.0061	0.3192	0.106
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Entamoeba histolytica	protein kinase, putative	0.0061	0.3192	0.3216
Loa Loa (eye worm)	TK/FER protein kinase	0.0061	0.3192	0.106
Echinococcus multilocularis	tyrosine protein kinase	0.0061	0.3192	0.106
Echinococcus multilocularis	insulin growth factor 1 receptor beta	0.0061	0.3192	0.106
Schistosoma mansoni	tyrosine kinase	0.0061	0.3192	0.106
Trichomonas vaginalis	serine/threonine-protein kinase wnk, putative	0.0061	0.3192	1
Loa Loa (eye worm)	TK/EGFR protein kinase	0.0061	0.3192	0.106
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0061	0.3192	0.105
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0103	0.9925	0.9901
Toxoplasma gondii	protein kinase domain-containing protein	0.0061	0.3192	0.9139
Echinococcus granulosus	receptor type guanylyl cyclase	0.0061	0.3192	0.105
Echinococcus granulosus	mitogen-activated protein kinase kinase kinase 9	0.0061	0.3192	0.105
Echinococcus granulosus	tyrosine protein kinase HCK	0.0061	0.3192	0.105
Echinococcus multilocularis	kinase suppressor of Ras 1	0.0061	0.3192	0.106
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Entamoeba histolytica	hypothetical protein	0.0061	0.3192	0.3216
Entamoeba histolytica	hypothetical protein	0.0061	0.3192	0.3216
Entamoeba histolytica	serine/threonine kinase, putative	0.0061	0.3192	0.3216
Entamoeba histolytica	tyrosine kinase, putative	0.0061	0.3192	0.3216
Loa Loa (eye worm)	TK/FER protein kinase	0.0103	0.9925	1
Trypanosoma cruzi	protein kinase, putative	0.0061	0.3192	0.9139
Trypanosoma brucei	AGC/RSK family serine/threonine kinase, putative	0.0061	0.3192	0.9139
Schistosoma mansoni	tyrosine kinase	0.0061	0.3192	0.106
Trichomonas vaginalis	conserved hypothetical protein	0.0061	0.3192	1
Trichomonas vaginalis	br serine/threonine-protein kinase, putative	0.0061	0.3192	1
Brugia malayi	bone morphogenetic protein type 1 receptor	0.0061	0.3192	0.106
Brugia malayi	Protein kinase domain containing protein	0.0061	0.3192	0.106
Entamoeba histolytica	serine/threonine kinase, putative	0.0061	0.3192	0.3216
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0061	0.3192	1
Entamoeba histolytica	protein kinase domain containing protein	0.0061	0.3192	0.3216
Entamoeba histolytica	tyrosine- protein kinase 2, putative	0.0061	0.3192	0.3216
Echinococcus multilocularis	tyrosine protein kinase csk	0.0061	0.3192	0.106
Loa Loa (eye worm)	TK/FER protein kinase	0.0061	0.3192	0.106
Loa Loa (eye worm)	TK protein kinase	0.0061	0.3192	0.106
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Echinococcus granulosus	tyrosine protein kinase Fes:Fps	0.0061	0.3192	0.105
Giardia lamblia	Kinase, NEK	0.0061	0.3192	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0061	0.3192	0.3216
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Entamoeba histolytica	serine/threonine kinase, putative	0.0061	0.3192	0.3216
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0061	0.3192	0.106
Brugia malayi	Protein kinase domain containing protein	0.0061	0.3192	0.106
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Brugia malayi	Tyrosine-protein kinase PR2	0.0061	0.3192	0.106
Echinococcus multilocularis	basic fibroblast growth factor receptor 1 A	0.0061	0.3192	0.106
Trichomonas vaginalis	conserved hypothetical protein	0.0061	0.3192	1
Echinococcus multilocularis	tyrosine protein kinase shark	0.0103	0.9925	1
Echinococcus multilocularis	epidermal growth factor receptor	0.0061	0.3192	0.106
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Entamoeba histolytica	tyrosine kinase, putative	0.0061	0.3192	0.3216
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Schistosoma mansoni	tyrosine kinase	0.0061	0.3192	0.106
Entamoeba histolytica	tyrosin kinase, putative	0.0061	0.3192	0.3216
Loa Loa (eye worm)	TKL/STKR/TYPE1 protein kinase	0.0061	0.3192	0.106
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0103	0.9925	0.9901
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0062	0.3267	1
Schistosoma mansoni	tyrosine kinase	0.0061	0.3192	0.106
Loa Loa (eye worm)	TK/RYK protein kinase	0.0061	0.3192	0.106
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Schistosoma mansoni	ephrin receptor	0.0061	0.3192	0.106
Echinococcus multilocularis	atrial natriuretic peptide receptor 1	0.0061	0.3192	0.106
Echinococcus granulosus	tyrosine protein kinase csk	0.0061	0.3192	0.105
Schistosoma mansoni	tyrosine protein kinase	0.0061	0.3192	0.106
Entamoeba histolytica	hypothetical protein	0.0061	0.3192	0.3216
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0061	0.3192	0.106
Loa Loa (eye worm)	TK/FER protein kinase	0.0061	0.3192	0.106
Loa Loa (eye worm)	TK/FER protein kinase	0.0103	0.9925	1
Echinococcus multilocularis	tyrosine protein kinase Srms	0.0103	0.9925	1
Brugia malayi	Protein kinase domain containing protein	0.0103	0.9925	1
Loa Loa (eye worm)	TK protein kinase	0.0061	0.3192	0.106
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0103	0.9925	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0061	0.3192	0.106
Echinococcus granulosus	tyrosine protein kinase Fps85D	0.0103	0.9925	0.9901
Echinococcus multilocularis	receptor type guanylyl cyclase	0.0061	0.3192	0.106
Schistosoma mansoni	serine/threonine protein kinase	0.0061	0.3192	0.106
Echinococcus multilocularis	FL cytokine receptor	0.0061	0.3192	0.106
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0061	0.3192	0.106
Schistosoma mansoni	tyrosine kinase	0.0061	0.3192	0.106
Brugia malayi	Guanylyl cyclase protein 23	0.0061	0.3192	0.106
Trypanosoma brucei	protein kinase, putative	0.0062	0.3267	1
Entamoeba histolytica	protein kinase, putative	0.0061	0.3192	0.3216
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Echinococcus granulosus	3'partial\|retinal guanylyl cyclase 2	0.0061	0.3192	0.105
Entamoeba histolytica	hypothetical protein	0.0061	0.3192	0.3216
Entamoeba histolytica	protein kinase domain containing protein	0.0061	0.3192	0.3216
Entamoeba histolytica	protein kinase, putative	0.0061	0.3192	0.3216
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Brugia malayi	Protein kinase domain containing protein	0.0061	0.3192	0.106
Entamoeba histolytica	tyrosine kinase, putative	0.0061	0.3192	0.3216
Echinococcus granulosus	protein tyrosine kinase	0.0061	0.3192	0.105
Echinococcus granulosus	insulin growth factor 1 receptor beta	0.0061	0.3192	0.105
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0061	0.3192	0.106
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Loa Loa (eye worm)	serine/threonine protein kinase	0.0061	0.3192	0.106
Echinococcus granulosus	tyrosine protein kinase Src64B	0.0103	0.9925	0.9901
Loa Loa (eye worm)	hypothetical protein	0.0103	0.9925	1
Entamoeba histolytica	tyrosin kinase, putative	0.0061	0.3192	0.3216
Echinococcus granulosus	fibroblast growth factor receptor 4	0.0061	0.3192	0.105
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Echinococcus granulosus	tyrosine protein kinase	0.0061	0.3192	0.105
Entamoeba histolytica	ankyrin repeat protein	0.0061	0.3192	0.3216
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Loa Loa (eye worm)	TKL/MLK/HH498 protein kinase	0.0061	0.3192	0.106
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.0103	0.9925	1
Echinococcus granulosus	kinase suppressor of Ras 1	0.0061	0.3192	0.105
Schistosoma mansoni	protein kinase	0.0061	0.3192	0.106
Trypanosoma brucei	STE/STE11 serine/threonine-protein kinase, putative	0.0062	0.3267	1
Echinococcus multilocularis	raf serine:threonine protein kinase	0.0061	0.3192	0.106
Entamoeba histolytica	protein kinase domain containing protein	0.0061	0.3192	0.3216
Echinococcus multilocularis	protein kinase	0.0061	0.3192	0.106
Echinococcus multilocularis	protein tyrosine kinase	0.0061	0.3192	0.106
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0061	0.3192	0.3216
Schistosoma mansoni	serine/threonine protein kinase	0.0061	0.3192	0.106
Brugia malayi	Protein kinase domain containing protein	0.0103	0.9925	1
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.0103	0.9925	1
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0061	0.3192	0.105
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Entamoeba histolytica	protein kinase domain containing protein	0.0061	0.3192	0.3216
Entamoeba histolytica	serine/threonine- protein kinase 6, putative	0.0056	0.2393	0.2411
Schistosoma mansoni	tyrosine kinase	0.0061	0.3192	0.106
Echinococcus granulosus	natriuretic peptide receptor 1	0.0061	0.3192	0.105
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Entamoeba histolytica	tyrosine kinase, putative	0.0061	0.3192	0.3216
Entamoeba histolytica	receptor protein kinase, putative	0.0061	0.3192	0.3216
Trypanosoma brucei	Flagellum attachment zone protein 20	0.0061	0.3192	0.9139
Onchocerca volvulus		0.0103	0.9925	1
Echinococcus granulosus	tyrosine protein kinase ABL1	0.0103	0.9925	0.9901
Echinococcus multilocularis	natriuretic peptide receptor 1	0.0061	0.3192	0.106
Entamoeba histolytica	protein kinase , putative	0.0056	0.2393	0.2411
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Echinococcus granulosus	tyrosine protein kinase pr2	0.0061	0.3192	0.105
Brugia malayi	Protein kinase domain containing protein	0.0061	0.3192	0.106
Loa Loa (eye worm)	TKL/MLK/ILK protein kinase	0.0061	0.3192	0.106
Loa Loa (eye worm)	TK/FER protein kinase	0.0061	0.3192	0.106
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.0103	0.9925	0.9901
Schistosoma mansoni	tyrosine kinase	0.0103	0.9925	1
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.0103	0.9925	0.9901
Entamoeba histolytica	protein kinase domain containing protein	0.0061	0.3192	0.3216
Loa Loa (eye worm)	TK/FER protein kinase	0.0061	0.3192	0.106
Entamoeba histolytica	ankyrin repeat protein	0.0061	0.3192	0.3216
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Trypanosoma cruzi	protein kinase, putative	0.0061	0.3192	0.9139
Loa Loa (eye worm)	protein kinase domain-containing protein	0.0061	0.3192	0.106
Entamoeba histolytica	protein kinase domain containing protein	0.0061	0.3192	0.3216
Entamoeba histolytica	protein kinase domain containing protein	0.0061	0.3192	0.3216
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0062	0.3267	1
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0061	0.3192	0.106
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Echinococcus granulosus	melanoma receptor tyrosine protein kinase	0.0061	0.3192	0.105
Echinococcus multilocularis	transfer RNA-Thr	0.0061	0.3192	0.106
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0061	0.3192	0.105
Echinococcus granulosus	activated cdc42 kinase 1	0.0061	0.3192	0.105
Entamoeba histolytica	tyrosine kinase, putative	0.0061	0.3192	0.3216
Onchocerca volvulus		0.0103	0.9925	1
Trypanosoma brucei	Pseudokinase, putative	0.0061	0.3192	0.9139
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Brugia malayi	Protein kinase domain containing protein	0.0103	0.9925	1
Entamoeba histolytica	tyrosine kinase, putative	0.0061	0.3192	0.3216
Echinococcus multilocularis	tyrosine protein kinase Blk	0.0103	0.9925	1
Brugia malayi	Protein kinase domain containing protein	0.0061	0.3192	0.106
Echinococcus granulosus	ephrin type A receptor 4 A	0.0061	0.3192	0.105
Entamoeba histolytica	protein kinase, putative	0.0061	0.3192	0.3216
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0061	0.3192	0.3216
Schistosoma mansoni	tyrosine kinase	0.0103	0.9925	1
Entamoeba histolytica	serine/threonine kinase, putative	0.0061	0.3192	0.3216
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0061	0.3192	0.3216
Entamoeba histolytica	tyrosine kinase, putative	0.0061	0.3192	0.3216
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0103	0.9925	1
Echinococcus multilocularis	tyrosine protein kinase HCK	0.0061	0.3192	0.106
Echinococcus granulosus	integrin linked protein kinase	0.0061	0.3192	0.105
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.0103	0.9925	1
Entamoeba histolytica	tyrosin kinase, putative	0.0061	0.3192	0.3216
Entamoeba histolytica	cysteine surface protein, putative	0.0061	0.3192	0.3216
Entamoeba histolytica	protein kinase, putative	0.0056	0.2393	0.2411
Schistosoma mansoni	tyrosine kinase	0.0061	0.3192	0.106
Schistosoma mansoni	tyrosine kinase	0.0061	0.3192	0.106
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0061	0.3192	0.106
Loa Loa (eye worm)	SRC-1	0.0103	0.9925	1
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Echinococcus granulosus	tyrosine kinase	0.0103	0.9925	0.9901
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0061	0.3192	0.3216
Entamoeba histolytica	hypothetical protein	0.0061	0.3192	0.3216
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0103	0.9925	1
Loa Loa (eye worm)	hypothetical protein	0.0061	0.3192	0.106
Trichomonas vaginalis	STE family protein kinase	0.0061	0.3192	1
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0061	0.3192	0.106
Brugia malayi	Receptor family ligand binding region containing protein	0.0061	0.3192	0.106
Entamoeba histolytica	tyrosine kinase, putative	0.0061	0.3192	0.3216
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.0103	0.9925	1
Brugia malayi	Protein kinase domain containing protein	0.0061	0.3192	0.106
Entamoeba histolytica	protein kinase domain containing protein	0.0061	0.3192	0.3216
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Echinococcus granulosus	tyrosine protein kinase Srms	0.0103	0.9925	0.9901
Entamoeba histolytica	protein kinase domain containing protein	0.0056	0.2393	0.2411
Loa Loa (eye worm)	TK/FER protein kinase	0.0103	0.9925	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0061	0.3192	0.3216
Echinococcus granulosus	dual specificity testis-specific protein kinase	0.0062	0.3267	0.1149
Trichomonas vaginalis	CAMK family protein kinase	0.0061	0.3192	1
Entamoeba histolytica	protein kinase, putative	0.0061	0.3192	0.3216
Echinococcus granulosus	basic fibroblast growth factor receptor 1 A	0.0061	0.3192	0.105
Brugia malayi	Protein kinase domain containing protein	0.0061	0.3192	0.106
Echinococcus multilocularis	tyrosine protein kinase pr2	0.0061	0.3192	0.106
Leishmania major	protein kinase, putative	0.0061	0.3192	0.9139
Entamoeba histolytica	protein kinase, putative	0.0061	0.3192	0.3216
Brugia malayi	Protein kinase domain containing protein	0.0061	0.3192	0.106
Echinococcus granulosus	protein kinase	0.0061	0.3192	0.105
Entamoeba histolytica	serine/threonine protein kinase 6, putative	0.0056	0.2393	0.2411
Giardia lamblia	Protein 21.1	0.0061	0.3192	1
Entamoeba histolytica	protein kinase domain containing protein	0.0061	0.3192	0.3216
Brugia malayi	Protein kinase domain containing protein	0.0061	0.3192	0.106
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Schistosoma mansoni	tyrosine kinase	0.0061	0.3192	0.106
Entamoeba histolytica	protein kinase domain containing protein	0.0061	0.3192	0.3216
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0103	0.9925	1
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Echinococcus granulosus	tyrosine kinase	0.0103	0.9925	0.9901
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Entamoeba histolytica	protein kinase domain containing protein	0.0061	0.3192	0.3216
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Schistosoma mansoni	serine/threonine RGC	0.0061	0.3192	0.106
Trichomonas vaginalis	conserved hypothetical protein	0.0061	0.3192	1
Echinococcus multilocularis	dual specificity testis specific protein kinase	0.0062	0.3267	0.116
Entamoeba histolytica	hypothetical protein	0.0061	0.3192	0.3216
Trichomonas vaginalis	conserved hypothetical protein	0.0061	0.3192	1
Schistosoma mansoni	protein kinase	0.0062	0.3267	0.116
Loa Loa (eye worm)	TK/FER protein kinase	0.0103	0.9925	1
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Schistosoma mansoni	hypothetical protein	0.0061	0.3192	0.106
Brugia malayi	Protein kinase domain containing protein	0.0061	0.3192	0.106
Echinococcus multilocularis	macrophage colony stimulating factor 1 receptor	0.0061	0.3192	0.106
Loa Loa (eye worm)	TK/FER protein kinase	0.0103	0.9925	1
Schistosoma mansoni	tyrosine kinase	0.0061	0.3192	0.106
Loa Loa (eye worm)	TK/FER protein kinase	0.0103	0.9925	1
Schistosoma mansoni	protein kinase	0.0062	0.3267	0.116
Loa Loa (eye worm)	hypothetical protein	0.0061	0.3192	0.106
Schistosoma mansoni	src-type protein tyrosine kinase-related	0.0061	0.3192	0.106
Brugia malayi	SH2 domain containing protein	0.0103	0.9925	1
Brugia malayi	Protein kinase domain containing protein	0.0061	0.3192	0.106
Loa Loa (eye worm)	TK/FER protein kinase	0.0103	0.9925	1
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Echinococcus granulosus	activin receptor type	0.0062	0.3267	0.1149
Loa Loa (eye worm)	TK/KIN6 protein kinase	0.0061	0.3192	0.106
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Schistosoma mansoni	tyrosine kinase	0.0061	0.3192	0.106
Entamoeba histolytica	serine/threonine kinase, putative	0.0061	0.3192	0.3216
Schistosoma mansoni	tyrosine kinase	0.0061	0.3192	0.106
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Echinococcus multilocularis	epidermal growth factor receptor	0.0061	0.3192	0.106
Echinococcus multilocularis	protein kinase	0.0061	0.3192	0.106
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Schistosoma mansoni	serine/threonine protein kinase	0.0061	0.3192	0.106
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.0103	0.9925	1
Echinococcus multilocularis	tyrosine protein kinase csk	0.0061	0.3192	0.106
Loa Loa (eye worm)	TK protein kinase	0.0061	0.3192	0.106
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0061	0.3192	1
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0103	0.9925	0.9901
Echinococcus multilocularis	tyrosine protein kinase Abl	0.0103	0.9925	1
Entamoeba histolytica	protein kinase domain containing protein	0.0061	0.3192	0.3216
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Entamoeba histolytica	protein kinase, putative	0.0056	0.2393	0.2411
Brugia malayi	C-terminal src kinase protein 1	0.0061	0.3192	0.106
Entamoeba histolytica	tyrosine kinase, putative	0.0061	0.3192	0.3216
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Loa Loa (eye worm)	TK protein kinase	0.0061	0.3192	0.106
Schistosoma mansoni	protein kinase	0.0061	0.3192	0.106
Echinococcus granulosus	tyrosine protein kinase shark	0.0103	0.9925	0.9901
Entamoeba histolytica	protein kinase domain containing protein	0.0061	0.3192	0.3216
Brugia malayi	Furin-like cysteine rich region family protein	0.0061	0.3192	0.106
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Echinococcus granulosus	tyrosine protein kinase Blk	0.0103	0.9925	0.9901
Schistosoma mansoni	tyrosine kinase	0.0061	0.3192	0.106
Echinococcus multilocularis	fibroblast growth factor receptor 4	0.0061	0.3192	0.106
Echinococcus multilocularis	activated cdc42 kinase 1	0.0061	0.3192	0.106
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Echinococcus granulosus	epidermal growth factor receptor	0.0061	0.3192	0.105
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0061	0.3192	0.106
Entamoeba histolytica	protein kinase domain containing protein	0.0061	0.3192	0.3216
Giardia lamblia	Kinase, NEK	0.0061	0.3192	1
Echinococcus multilocularis	activin receptor type	0.0062	0.3267	0.116
Trichomonas vaginalis	conserved hypothetical protein	0.0061	0.3192	1
Entamoeba histolytica	protein kinase domain containing protein	0.0062	0.3267	0.3292
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0103	0.9925	0.9901
Loa Loa (eye worm)	TK/FER protein kinase	0.0103	0.9925	1
Entamoeba histolytica	receptor protein kinase, putative	0.0061	0.3192	0.3216
Schistosoma mansoni	tyrosine kinase	0.0061	0.3192	0.106
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Brugia malayi	Protein kinase domain containing protein	0.0061	0.3192	0.106
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0061	0.3192	0.106
Brugia malayi	hypothetical protein	0.0061	0.3192	0.106
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.0103	0.9925	1
Echinococcus granulosus	epidermal growth factor receptor	0.0061	0.3192	0.105
Loa Loa (eye worm)	TK/DDR protein kinase	0.0061	0.3192	0.106
Loa Loa (eye worm)	hypothetical protein	0.0061	0.3192	0.106
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.0103	0.9925	1
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0061	0.3192	0.106
Entamoeba histolytica	serine/threonine kinase, putative	0.0061	0.3192	0.3216
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0077	0.5721	0.4419
Entamoeba histolytica	tyrosine kinase, putative	0.0061	0.3192	0.3216
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Brugia malayi	Tyrosine-protein kinase F09A5.2 in chromosome X, putative	0.0061	0.3192	0.106
Schistosoma mansoni	tyrosine kinase	0.0103	0.9925	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0061	0.3192	0.3216
Loa Loa (eye worm)	TK/ABL protein kinase	0.0103	0.9925	1
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0061	0.3192	0.106
Loa Loa (eye worm)	TK protein kinase	0.0061	0.3192	0.106
Echinococcus multilocularis	tyrosine kinase	0.0103	0.9925	1
Echinococcus multilocularis	tyrosine protein kinase Fes:Fps	0.0061	0.3192	0.106
Echinococcus granulosus	raf serine:threonine protein kinase	0.0061	0.3192	0.105
Echinococcus multilocularis	heat shock protein 70	0.0061	0.3192	0.106
Loa Loa (eye worm)	TK protein kinase	0.0061	0.3192	0.106
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Loa Loa (eye worm)	TKL/RAF/RAF protein kinase	0.0061	0.3192	0.106
Entamoeba histolytica	protein kinase, putative	0.0061	0.3192	0.3216
Trichomonas vaginalis	serine-threonine protein kinase, putative	0.0061	0.3192	1
Brugia malayi	Protein kinase domain containing protein	0.0061	0.3192	0.106
Schistosoma mansoni	tyrosine kinase	0.0061	0.3192	0.106
Loa Loa (eye worm)	TK/Met protein kinase	0.0061	0.3192	0.106
Loa Loa (eye worm)	TK/ROR protein kinase	0.0061	0.3192	0.106
Brugia malayi	Protein kinase domain containing protein	0.0061	0.3192	0.106
Brugia malayi	Protein kinase domain containing protein	0.0061	0.3192	0.106
Brugia malayi	Protein kinase domain containing protein	0.0061	0.3192	0.106
Loa Loa (eye worm)	TKL/RAF/KSR protein kinase	0.0061	0.3192	0.106
Echinococcus multilocularis	insulin receptor	0.0061	0.3192	0.106
Entamoeba histolytica	protein kinase, putative	0.0061	0.3192	0.3216
Loa Loa (eye worm)	TK protein kinase	0.0061	0.3192	0.106
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0061	0.3192	0.3216
Entamoeba histolytica	tyrosine kinase, putative	0.0061	0.3192	0.3216
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0103	0.9925	1
Brugia malayi	Protein kinase domain containing protein	0.0061	0.3192	0.106
Brugia malayi	ephrin receptor 1 precursor	0.0061	0.3192	0.106
Leishmania major	hypothetical protein, conserved	0.0061	0.3192	0.9139
Echinococcus granulosus	tyrosine protein kinase csk	0.0061	0.3192	0.105
Echinococcus multilocularis	tyrosine protein kinase csk	0.0061	0.3192	0.106
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0061	0.3192	0.105
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0061	0.3192	0.3216
Loa Loa (eye worm)	TK/FER protein kinase	0.0103	0.9925	1
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0103	0.9925	1
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0061	0.3192	0.105
Leishmania major	protein kinase, putative	0.0062	0.3267	1
Entamoeba histolytica	hypothetical protein	0.0061	0.3192	0.3216
Plasmodium falciparum	protein kinase, putative	0.0062	0.3267	1
Entamoeba histolytica	protein kinase, putative	0.0061	0.3192	0.3216
Entamoeba histolytica	hypothetical protein	0.0061	0.3192	0.3216
Schistosoma mansoni	tyrosine kinase	0.0061	0.3192	0.106
Entamoeba histolytica	serine/threonine- protein kinase 6 , putative	0.0056	0.2393	0.2411
Echinococcus multilocularis	tyrosine kinase	0.0061	0.3192	0.106
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Brugia malayi	Protein kinase domain containing protein	0.0061	0.3192	0.106
Echinococcus multilocularis	ephrin type A receptor 4 A	0.0061	0.3192	0.106
Echinococcus multilocularis	tyrosine protein kinase Fps85D	0.0103	0.9925	1
Entamoeba histolytica	protein kinase, putative	0.0061	0.3192	0.3216
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.0103	0.9925	0.9901
Echinococcus granulosus	macrophage colony stimulating factor 1 receptor	0.0061	0.3192	0.105
Entamoeba histolytica	protein kinase domain containing protein	0.0061	0.3192	0.3216
Plasmodium falciparum	protein kinase, putative	0.0061	0.3192	0.9139
Onchocerca volvulus		0.0103	0.9925	1
Schistosoma mansoni	tyrosine kinase	0.0103	0.9925	1
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0061	0.3192	0.106
Schistosoma mansoni	protein kinase	0.0061	0.3192	0.106
Schistosoma mansoni	ephrin receptor	0.0061	0.3192	0.106
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0061	0.3192	0.106
Plasmodium falciparum	tyrosine kinase-like protein	0.0061	0.3192	0.9139
Trichomonas vaginalis	protein kinase atn1, putative	0.0061	0.3192	1
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Entamoeba histolytica	tyrosine kinase, putative	0.0061	0.3192	0.3216
Loa Loa (eye worm)	TK/FER protein kinase	0.0103	0.9925	1
Entamoeba histolytica	protein kinase, putative	0.0061	0.3192	0.3216
Onchocerca volvulus		0.0103	0.9925	1
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Brugia malayi	Protein kinase domain containing protein	0.0103	0.9925	1
Trichomonas vaginalis	TKL family protein kinase	0.0061	0.3192	1
Loa Loa (eye worm)	TK/INSR protein kinase	0.0061	0.3192	0.106
Echinococcus granulosus	mitogen activated protein kinase kinase kinase	0.0061	0.3192	0.105

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL3139265

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1859962