Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | rac-beta serine/threonine protein kinase, putative | 0.0128 | 0.1989 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0068 | 0.0866 | 0.0233 |
Brugia malayi | Hr1 repeat family protein | 0.0066 | 0.0843 | 0.0843 |
Echinococcus multilocularis | protein kinase c iota type | 0.0066 | 0.0843 | 0.1783 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.2632 | 0.1953 |
Echinococcus multilocularis | rho associated protein kinase | 0.0182 | 0.2977 | 0.6293 |
Trichomonas vaginalis | AGC family protein kinase | 0.0066 | 0.0843 | 0.0139 |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.0193 | 0.3183 | 0.3183 |
Echinococcus multilocularis | serine threonine protein kinase nrc serine threonine protein kinase gad | 0.0128 | 0.1989 | 0.4206 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0066 | 0.0843 | 0.1783 |
Echinococcus granulosus | serine threonine protein kinase nrc | 0.0128 | 0.1989 | 0.4206 |
Loa Loa (eye worm) | AGC/DMPK/ROCK protein kinase | 0.0562 | 1 | 1 |
Echinococcus multilocularis | nervana 2 | 0.0127 | 0.1956 | 0.4135 |
Onchocerca volvulus | 0.0182 | 0.2977 | 1 | |
Trichomonas vaginalis | AGC family protein kinase | 0.0194 | 0.3205 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0066 | 0.0843 | 0.2833 |
Echinococcus multilocularis | nervana 2 | 0.0127 | 0.1956 | 0.4135 |
Toxoplasma gondii | AGC kinase | 0.0193 | 0.3183 | 0.5 |
Echinococcus granulosus | protein kinase C gamma type | 0.0066 | 0.0843 | 0.1783 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0066 | 0.0843 | 0.1783 |
Echinococcus multilocularis | serine:threonine protein kinase 38 | 0.0066 | 0.0843 | 0.1783 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0066 | 0.0843 | 0.1783 |
Entamoeba histolytica | protein kinase 2, putative | 0.0128 | 0.1989 | 0.6207 |
Trichomonas vaginalis | AGC family protein kinase | 0.0194 | 0.3205 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0066 | 0.0843 | 0.1783 |
Entamoeba histolytica | protein kinase, putative | 0.0194 | 0.3205 | 1 |
Brugia malayi | protein kinase C II. | 0.0066 | 0.0843 | 0.0843 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.013 | 0.2012 | 0.6277 |
Brugia malayi | Protein kinase domain containing protein | 0.0066 | 0.0843 | 0.0843 |
Schistosoma mansoni | serine/threonine kinase | 0.0066 | 0.0843 | 0.2833 |
Echinococcus multilocularis | Ribosomal protein S6 kinase beta 2 | 0.0066 | 0.0843 | 0.1783 |
Trichomonas vaginalis | AGC family protein kinase | 0.0194 | 0.3205 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0194 | 0.3205 | 1 |
Onchocerca volvulus | 0.018 | 0.2943 | 0.9033 | |
Schistosoma mansoni | serine/threonine-protein kinase | 0.013 | 0.2012 | 0.6759 |
Echinococcus multilocularis | ribosomal protein s6 kinase beta 1 | 0.0066 | 0.0843 | 0.1783 |
Entamoeba histolytica | protein kinase, putative | 0.0066 | 0.0843 | 0.2631 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0066 | 0.0843 | 0.1783 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0066 | 0.0843 | 0.2833 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase | 0.0128 | 0.1989 | 0.4206 |
Schistosoma mansoni | atypical protein kinase C | 0.0066 | 0.0843 | 0.2833 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.013 | 0.2012 | 0.6759 |
Trichomonas vaginalis | AGC family protein kinase | 0.0066 | 0.0843 | 0.0139 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0277 | 0.473 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0066 | 0.0843 | 0.2833 |
Echinococcus granulosus | rho-associated protein kinase 1 | 0.0182 | 0.2977 | 0.6293 |
Echinococcus multilocularis | rac serine:threonine kinase | 0.013 | 0.2012 | 0.4253 |
Plasmodium falciparum | RAC-beta serine/threonine protein kinase | 0.0128 | 0.1989 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0066 | 0.0843 | 0.2833 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0066 | 0.0843 | 0.1783 |
Echinococcus granulosus | Ribosomal protein S6 kinase beta 2 | 0.0066 | 0.0843 | 0.1783 |
Echinococcus granulosus | serine/threonine protein kinase | 0.013 | 0.2012 | 0.4253 |
Brugia malayi | Protein kinase domain containing protein | 0.0066 | 0.0843 | 0.0843 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0066 | 0.0843 | 0.1783 |
Trypanosoma cruzi | Protein kinase B | 0.013 | 0.2012 | 1 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0277 | 0.473 | 1 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.013 | 0.2012 | 1 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0127 | 0.1956 | 0.4135 |
Echinococcus granulosus | ribosomal protein s6 kinase beta 1 | 0.0066 | 0.0843 | 0.1783 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0194 | 0.3205 | 0.2579 |
Brugia malayi | Myb-like DNA-binding domain containing protein | 0.0158 | 0.2546 | 0.2546 |
Echinococcus granulosus | nervana 2 | 0.0127 | 0.1956 | 0.4135 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0194 | 0.3205 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0194 | 0.3205 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0066 | 0.0843 | 0.2833 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0066 | 0.0843 | 0.1783 |
Entamoeba histolytica | protein kinase, putative | 0.0194 | 0.3205 | 1 |
Echinococcus granulosus | neuropeptide s receptor | 0.0277 | 0.473 | 1 |
Echinococcus multilocularis | ribosomal protein S6 kinase alpha 3 | 0.0066 | 0.0843 | 0.1783 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0277 | 0.473 | 1 |
Echinococcus granulosus | protein kinase c iota type | 0.0066 | 0.0843 | 0.1783 |
Echinococcus granulosus | ribosomal protein S6 kinase alpha 3 | 0.0066 | 0.0843 | 0.1783 |
Echinococcus multilocularis | Glutaredoxin protein 5 | 0.0127 | 0.1956 | 0.4135 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.013 | 0.2012 | 0.6277 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0066 | 0.0843 | 0.2833 |
Echinococcus granulosus | nervana 2 | 0.0127 | 0.1956 | 0.4135 |
Brugia malayi | Protein kinase domain containing protein | 0.0194 | 0.3205 | 0.3205 |
Echinococcus granulosus | Glutaredoxin protein 5 | 0.0127 | 0.1956 | 0.4135 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0182 | 0.2977 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0194 | 0.3205 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0066 | 0.0843 | 0.0139 |
Entamoeba histolytica | protein kinase, putative | 0.0193 | 0.3183 | 0.993 |
Loa Loa (eye worm) | hypothetical protein | 0.0158 | 0.2546 | 0.186 |
Trichomonas vaginalis | AGC family protein kinase | 0.0194 | 0.3205 | 1 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0127 | 0.1956 | 0.4135 |
Echinococcus granulosus | NDR protein kinase | 0.0066 | 0.0843 | 0.1783 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0066 | 0.0843 | 0.2833 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0193 | 0.3183 | 0.2555 |
Giardia lamblia | Kinase, AGC PKA | 0.0128 | 0.1989 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.