Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Intermediate filament tail domain containing protein | 0.0033 | 0.4341 | 0.4129 |
Echinococcus multilocularis | lamin | 0.0033 | 0.4341 | 0.3011 |
Schistosoma mansoni | lamin | 0.0033 | 0.4341 | 0.3011 |
Echinococcus multilocularis | dna polymerase eta | 0.0054 | 1 | 1 |
Schistosoma mansoni | lamin | 0.0033 | 0.4341 | 0.3011 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0054 | 1 | 1 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0033 | 0.4341 | 0.4129 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.1904 | 0.1904 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0023 | 0.1904 | 0.5 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0023 | 0.1904 | 0.16 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.1904 | 0.1904 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.1904 | 0.1904 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0038 | 0.577 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.1904 | 0.1904 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0023 | 0.1904 | 0.1904 |
Loa Loa (eye worm) | intermediate filament protein | 0.0033 | 0.4341 | 0.4129 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.1904 | 0.1904 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0023 | 0.1904 | 0.1904 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0023 | 0.1904 | 0.5 |
Echinococcus multilocularis | musashi | 0.0033 | 0.4341 | 0.3011 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0023 | 0.1904 | 0.5 |
Schistosoma mansoni | intermediate filament proteins | 0.0033 | 0.4341 | 0.3011 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.4341 | 0.4129 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.1904 | 0.1904 |
Trypanosoma brucei | unspecified product | 0.0023 | 0.1904 | 0.1904 |
Onchocerca volvulus | 0.0033 | 0.4341 | 0.5 | |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0038 | 0.577 | 0.4775 |
Brugia malayi | intermediate filament protein | 0.0033 | 0.4341 | 0.4129 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.1904 | 0.1904 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0054 | 1 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0023 | 0.1904 | 0.5 |
Echinococcus granulosus | intermediate filament protein | 0.0033 | 0.4341 | 0.3011 |
Echinococcus granulosus | dna polymerase eta | 0.0054 | 1 | 1 |
Schistosoma mansoni | DNA polymerase eta | 0.0054 | 1 | 1 |
Onchocerca volvulus | 0.0033 | 0.4341 | 0.5 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.1904 | 0.1904 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.1904 | 0.1904 |
Echinococcus granulosus | lamin dm0 | 0.0033 | 0.4341 | 0.3011 |
Echinococcus multilocularis | lamin dm0 | 0.0033 | 0.4341 | 0.3011 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0023 | 0.1904 | 0.5 |
Leishmania major | DNA polymerase eta, putative | 0.0038 | 0.577 | 0.4775 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0023 | 0.1904 | 0.5 |
Giardia lamblia | DINP protein human, muc B family | 0.0023 | 0.1904 | 0.5 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0023 | 0.1904 | 0.16 |
Echinococcus granulosus | lamin | 0.0033 | 0.4341 | 0.3011 |
Leishmania major | DNA polymerase eta, putative | 0.0054 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.4184 | 0.3966 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0023 | 0.1904 | 0.5 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0023 | 0.1904 | 0.1904 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.1904 | 0.1904 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.