Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.0333 | 0.5009 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0208 | 0.2764 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0208 | 0.2764 | 1 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.0359 | 0.5463 | 1 |
Mycobacterium leprae | probable zinc metalloprotease | 0.0208 | 0.2764 | 0.5 |
Echinococcus granulosus | endothelin converting enzyme 1 | 0.0208 | 0.2764 | 0.0996 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0164 | 0.1964 | 0.5758 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.1788 | 0.4828 |
Loa Loa (eye worm) | carboxylesterase | 0.0164 | 0.1964 | 0.5758 |
Schistosoma mansoni | neprilysin-2 (M13 family) | 0.0105 | 0.0911 | 0.3296 |
Brugia malayi | Peptidase family M13 containing protein | 0.0208 | 0.2764 | 1 |
Onchocerca volvulus | 0.0103 | 0.0877 | 0.5 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0164 | 0.1964 | 0.7104 |
Loa Loa (eye worm) | hypothetical protein | 0.0158 | 0.1853 | 0.5172 |
Echinococcus multilocularis | endothelin converting enzyme 1 | 0.0208 | 0.2764 | 0.0996 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.1788 | 0.4828 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0611 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0158 | 0.1853 | 0.5172 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.0154 | 0.1788 | 0.4828 |
Loa Loa (eye worm) | hypothetical protein | 0.0158 | 0.1853 | 0.5172 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.0359 | 0.5463 | 1 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0105 | 0.0911 | 0.3296 |
Loa Loa (eye worm) | hypothetical protein | 0.0158 | 0.1853 | 0.5172 |
Loa Loa (eye worm) | hypothetical protein | 0.0158 | 0.1853 | 0.5172 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.0154 | 0.1788 | 0.4828 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.1788 | 0.4828 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0208 | 0.2764 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.1964 | 0.5758 |
Loa Loa (eye worm) | hypothetical protein | 0.0158 | 0.1853 | 0.5172 |
Loa Loa (eye worm) | hypothetical protein | 0.0208 | 0.2764 | 1 |
Schistosoma mansoni | Nep2 peptidase (M13 family) | 0.0105 | 0.0911 | 0.3296 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.1964 | 0.5758 |
Toxoplasma gondii | peptidase family M13 protein | 0.0208 | 0.2764 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.1788 | 0.4828 |
Brugia malayi | Hypothetical zinc metalloproteinase T16A9.4 | 0.0208 | 0.2764 | 1 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0105 | 0.0911 | 0.3296 |
Schistosoma mansoni | family M13 non-peptidase homologue (M13 family) | 0.0105 | 0.0911 | 0.3296 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.