Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.0121 | 0.0987 | 0.1534 |
Leishmania major | proteasome beta 5 subunit, putative | 0.0265 | 0.6437 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0164 | 0.2604 | 0.4046 |
Brugia malayi | proteasome subunit beta type 2 | 0.0121 | 0.0987 | 0.1534 |
Entamoeba histolytica | probable proteasome subunit beta type 2, putative | 0.0121 | 0.0987 | 0.1534 |
Brugia malayi | Proteasome A-type and B-type family protein | 0.0265 | 0.6437 | 1 |
Plasmodium falciparum | proteasome subunit beta type-2, putative | 0.0121 | 0.0987 | 0.1534 |
Trypanosoma cruzi | 20S proteasome subunit | 0.0121 | 0.0987 | 0.1534 |
Trypanosoma brucei | proteasome subunit beta type-2, putative | 0.0121 | 0.0987 | 0.1534 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0265 | 0.6437 | 1 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.0121 | 0.0987 | 0.1534 |
Loa Loa (eye worm) | proteasome subunit beta type 2 | 0.0121 | 0.0987 | 0.1534 |
Giardia lamblia | Proteasome subunit beta type 5 precursor | 0.0265 | 0.6437 | 1 |
Mycobacterium leprae | proteasome (beta subunit) PrcB | 0.0265 | 0.6437 | 0.5 |
Toxoplasma gondii | proteasome subunit beta type, putative | 0.0265 | 0.6437 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0164 | 0.2604 | 0.4046 |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.0121 | 0.0987 | 0.1534 |
Trypanosoma cruzi | proteasome subunit beta type-2, putative | 0.0121 | 0.0987 | 0.1534 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.0333 | 0.9042 | 1 |
Echinococcus granulosus | proteasome prosome macropain | 0.0265 | 0.6437 | 1 |
Schistosoma mansoni | proteasome catalytic subunit 3 (T01 family) | 0.0265 | 0.6437 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0164 | 0.2604 | 0.4046 |
Plasmodium vivax | proteasome subunit beta type-5, putative | 0.0265 | 0.6437 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0164 | 0.2604 | 0.4046 |
Leishmania major | proteasome beta 2 subunit, putative | 0.0121 | 0.0987 | 0.1534 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0265 | 0.6437 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0164 | 0.2604 | 0.4046 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0121 | 0.0987 | 0.1534 |
Echinococcus granulosus | carboxylesterase 5A | 0.0164 | 0.2604 | 0.4046 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0265 | 0.6437 | 1 |
Toxoplasma gondii | proteasome subunit beta type 2, putative | 0.0121 | 0.0987 | 0.1534 |
Plasmodium falciparum | proteasome subunit beta type-5 | 0.0265 | 0.6437 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0164 | 0.2604 | 0.4046 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0164 | 0.2604 | 0.4046 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0121 | 0.0987 | 0.1534 |
Brugia malayi | Carboxylesterase family protein | 0.0164 | 0.2604 | 0.4046 |
Echinococcus multilocularis | acetylcholinesterase | 0.0164 | 0.2604 | 0.4046 |
Giardia lamblia | Proteasome subunit beta type 2 | 0.0121 | 0.0987 | 0.1534 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0265 | 0.6437 | 1 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.0121 | 0.0987 | 0.1534 |
Echinococcus multilocularis | proteasome (prosome, macropain) | 0.0265 | 0.6437 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.2604 | 0.4046 |
Trypanosoma brucei | proteasome subunit beta type-5, putative | 0.0265 | 0.6437 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0164 | 0.2604 | 0.4046 |
Entamoeba histolytica | proteasome subunit beta type 5 precursor, putative | 0.0265 | 0.6437 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.2604 | 0.4046 |
Plasmodium vivax | proteasome subunit beta type-2, putative | 0.0121 | 0.0987 | 0.1534 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.