Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0019 | 0.0316 | 0.4712 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0027 | 0.067 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.4217 | 0.4217 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0019 | 0.0316 | 0.0316 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0027 | 0.067 | 0.067 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0019 | 0.0316 | 0.0316 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0018 | 0.0285 | 0.0285 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0089 | 0.3396 | 0.3396 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0019 | 0.0316 | 0.0316 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0019 | 0.0316 | 0.0316 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0025 | 0.0572 | 1 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0027 | 0.067 | 1 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0092 | 0.3509 | 0.6668 |
Plasmodium vivax | SET domain protein, putative | 0.0019 | 0.0316 | 0.4712 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0025 | 0.0572 | 1 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0092 | 0.3509 | 0.3509 |
Brugia malayi | Pre-SET motif family protein | 0.0019 | 0.0316 | 0.06 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0132 | 0.5262 | 0.5262 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0025 | 0.0572 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0316 | 0.0316 |
Onchocerca volvulus | 0.0019 | 0.0316 | 0.0521 | |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0019 | 0.0316 | 0.0316 |
Trichomonas vaginalis | set domain proteins, putative | 0.015 | 0.6059 | 1 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0228 | 0.9487 | 0.9487 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0019 | 0.0316 | 0.0316 |
Brugia malayi | Pre-SET motif family protein | 0.0132 | 0.5262 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.4758 | 0.4758 |
Onchocerca volvulus | 0.015 | 0.6059 | 1 | |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0092 | 0.3509 | 0.3509 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0019 | 0.0316 | 0.0316 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0027 | 0.067 | 0.1106 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0027 | 0.067 | 1 |
Loa Loa (eye worm) | acetyltransferase | 0.0092 | 0.3509 | 0.3509 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0027 | 0.067 | 0.1106 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.