Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0049 | 0.0192 | 0.0194 |
Mycobacterium tuberculosis | Probable bifunctional purine biosynthesis protein PurH: phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transfo | 0.0293 | 1 | 1 |
Trichomonas vaginalis | glutaminase, putative | 0.0265 | 0.8876 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0192 | 0.0194 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0049 | 0.0192 | 0.0194 |
Loa Loa (eye worm) | glutaminase 2 | 0.0265 | 0.8876 | 0.8955 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0291 | 0.9912 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0291 | 0.9912 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0192 | 0.0194 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0192 | 0.0194 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0049 | 0.0192 | 0.0194 |
Schistosoma mansoni | gliotactin | 0.0049 | 0.0192 | 0.0194 |
Mycobacterium ulcerans | bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase | 0.0293 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | AICAR transformylase/IMP cyclohydrolase PurH | 0.0293 | 1 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0291 | 0.9912 | 1 |
Schistosoma mansoni | acetylcholinesterase | 0.0049 | 0.0192 | 0.0194 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0291 | 0.9912 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0291 | 0.9912 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0049 | 0.0192 | 0.0194 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0192 | 0.0194 |
Loa Loa (eye worm) | carboxylesterase | 0.0291 | 0.9912 | 1 |
Onchocerca volvulus | 0.0049 | 0.0192 | 0.5 | |
Loa Loa (eye worm) | carboxylesterase | 0.0049 | 0.0192 | 0.0194 |
Loa Loa (eye worm) | hypothetical protein | 0.0291 | 0.9912 | 1 |
Onchocerca volvulus | 0.0049 | 0.0192 | 0.5 | |
Onchocerca volvulus | 0.0049 | 0.0192 | 0.5 | |
Echinococcus multilocularis | acetylcholinesterase | 0.0291 | 0.9912 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0192 | 0.0194 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.016 | 0.0162 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0049 | 0.0192 | 0.0194 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0049 | 0.0192 | 0.0194 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0291 | 0.9912 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0049 | 0.0192 | 0.0194 |
Echinococcus granulosus | neuroligin | 0.0049 | 0.0192 | 0.0194 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.016 | 0.0162 |
Mycobacterium ulcerans | glutaminase | 0.0265 | 0.8876 | 0.8854 |
Brugia malayi | hypothetical protein | 0.0049 | 0.0192 | 0.0194 |
Brugia malayi | Carboxylesterase family protein | 0.0049 | 0.0192 | 0.0194 |
Loa Loa (eye worm) | carboxylesterase | 0.0049 | 0.0192 | 0.0194 |
Echinococcus multilocularis | acetylcholinesterase | 0.0291 | 0.9912 | 1 |
Brugia malayi | glutaminase DH11.1 | 0.0265 | 0.8876 | 0.8955 |
Onchocerca volvulus | 0.0049 | 0.0192 | 0.5 | |
Echinococcus multilocularis | neuroligin | 0.0049 | 0.0192 | 0.0194 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0049 | 0.0192 | 0.0194 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0192 | 0.0194 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0049 | 0.0192 | 0.0194 |
Schistosoma mansoni | glutaminase | 0.0265 | 0.8876 | 0.8955 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.016 | 0.0162 |
Onchocerca volvulus | 0.0049 | 0.0192 | 0.5 | |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0049 | 0.0192 | 0.0194 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0049 | 0.0192 | 0.0194 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0049 | 0.0192 | 0.0194 |
Echinococcus granulosus | acetylcholinesterase | 0.0291 | 0.9912 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0192 | 0.0194 |
Echinococcus granulosus | carboxylesterase 5A | 0.0291 | 0.9912 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0049 | 0.0192 | 0.0194 |
Echinococcus granulosus | acetylcholinesterase | 0.0291 | 0.9912 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.016 | 0.0162 |
Loa Loa (eye worm) | glutaminase | 0.0265 | 0.8876 | 0.8955 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0049 | 0.0192 | 0.0194 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.