Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | glycosyl hydrolase, putative | 0.0154 | 0.2117 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0318 | 1 | 1 |
Onchocerca volvulus | 0.0318 | 1 | 0.5 | |
Onchocerca volvulus | 0.0318 | 1 | 0.5 | |
Loa Loa (eye worm) | trehalase | 0.0318 | 1 | 1 |
Brugia malayi | Trehalase family protein | 0.0318 | 1 | 1 |
Mycobacterium leprae | Possible hydrolase | 0.0154 | 0.2117 | 0.5 |
Brugia malayi | Trehalase family protein | 0.0318 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0318 | 1 | 0.5 |
Leishmania major | glycosyl hydrolase, putative | 0.0154 | 0.2117 | 0.5 |
Onchocerca volvulus | Trehalase homolog | 0.0318 | 1 | 0.5 |
Brugia malayi | hypothetical protein | 0.0318 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0318 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0318 | 1 | 1 |
Onchocerca volvulus | 0.0318 | 1 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0318 | 1 | 1 |
Brugia malayi | Trehalase family protein | 0.0318 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0318 | 1 | 1 |
Loa Loa (eye worm) | trehalase | 0.0318 | 1 | 1 |
Loa Loa (eye worm) | TRE-1 protein | 0.0318 | 1 | 1 |
Loa Loa (eye worm) | trehalase | 0.0318 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0208 | 0.47 | 0.47 |
Onchocerca volvulus | 0.0318 | 1 | 0.5 | |
Loa Loa (eye worm) | TRE-2 protein | 0.0318 | 1 | 1 |
Treponema pallidum | hypothetical protein | 0.011 | 0 | 0.5 |
Mycobacterium tuberculosis | Conserved protein | 0.0154 | 0.2117 | 0.5 |
Onchocerca volvulus | 0.0318 | 1 | 0.5 | |
Mycobacterium ulcerans | glycosyl hydrolase | 0.0154 | 0.2117 | 0.5 |
Trichomonas vaginalis | trehalase, putative | 0.0318 | 1 | 0.5 |
Trypanosoma cruzi | glycosyl hydrolase, putative | 0.0154 | 0.2117 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.