Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Hexuronate transporter, putative | 0.004 | 1 | 0.5 |
Trichomonas vaginalis | Regulatory protein uhpC, putative | 0.004 | 1 | 0.5 |
Trichomonas vaginalis | Regulatory protein uhpC, putative | 0.004 | 1 | 0.5 |
Trichomonas vaginalis | glucarate, hexuronate transporter, putative | 0.004 | 1 | 0.5 |
Echinococcus granulosus | voltage gated sodium channel Nav1 alpha subunit | 0.0015 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable conserved integral membrane protein | 0.004 | 1 | 0.5 |
Echinococcus granulosus | sodium channel protein | 0.0015 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 1 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 1 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 1 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 1 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | major facilitator superfamily permease | 0.004 | 1 | 0.5 |
Leishmania major | calcium channel protein, putative,ion transporter, putative | 0.0015 | 0 | 0.5 |
Trichomonas vaginalis | glucarate, hexuronate transporter, putative | 0.004 | 1 | 0.5 |
Trichomonas vaginalis | transport proetin, putative | 0.004 | 1 | 0.5 |
Echinococcus multilocularis | sodium channel protein | 0.0015 | 0 | 0.5 |
Trichomonas vaginalis | glucose-6-phosphate translocase, putative | 0.004 | 1 | 0.5 |
Chlamydia trachomatis | hexose phosphate transporter | 0.004 | 1 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 1 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 1 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 1 | 0.5 |
Giardia lamblia | Sugar transport family protein | 0.004 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.