Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | alpha glucosidase II subunit, putative | 0.034 | 0.002 | 0.5 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.0745 | 0.3581 | 0.4257 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0514 | 0.1546 | 0.4309 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.0785 | 0.3929 | 0.4674 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0743 | 0.3561 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.034 | 0.002 | 0.5 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.0745 | 0.3581 | 0.4257 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0743 | 0.3561 | 1 |
Onchocerca volvulus | 0.0919 | 0.5106 | 1 | |
Echinococcus granulosus | ceramide glucosyltransferase | 0.0745 | 0.3581 | 0.3568 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0487 | 0.1315 | 0.3657 |
Onchocerca volvulus | Ceramide glucosyltransferase homolog | 0.0745 | 0.3581 | 0.5976 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0743 | 0.3561 | 1 |
Echinococcus multilocularis | non lysosomal glucosylceramidase | 0.0785 | 0.3929 | 0.3917 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0487 | 0.1315 | 0.3657 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0487 | 0.1315 | 0.3657 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.1475 | 1 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.1291 | 0.8384 | 1 |
Echinococcus granulosus | non lysosomal glucosylceramidase | 0.0785 | 0.3929 | 0.3917 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.1475 | 1 | 1 |
Echinococcus multilocularis | bile acid beta glucosidase | 0.0785 | 0.3929 | 0.3917 |
Echinococcus multilocularis | ceramide glucosyltransferase | 0.0745 | 0.3581 | 0.3568 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.0785 | 0.3929 | 0.4674 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.034 | 0.002 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.053 | 0.1687 | 0.167 |
Loa Loa (eye worm) | ceramide glucosyltransferase | 0.0745 | 0.3581 | 0.3568 |
Schistosoma mansoni | alpha-glucosidase | 0.1291 | 0.8384 | 1 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.034 | 0.002 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0487 | 0.1315 | 0.3657 |
Giardia lamblia | Ceramide glucosyltransferase | 0.0338 | 0 | 0.5 |
Brugia malayi | Ceramide glucosyltransferase | 0.0745 | 0.3581 | 0.3568 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0487 | 0.1315 | 0.3657 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0743 | 0.3561 | 1 |
Echinococcus granulosus | bile acid beta glucosidase | 0.0785 | 0.3929 | 0.3917 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0514 | 0.1546 | 0.4309 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0487 | 0.1315 | 0.3657 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.1475 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0743 | 0.3561 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.034 | 0.002 | 0.5 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0743 | 0.3561 | 0.3548 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.034 | 0.002 | 0.5 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0743 | 0.3561 | 0.3548 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.1475 | 1 | 1 |
Trypanosoma brucei | glucosidase, putative | 0.034 | 0.002 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0743 | 0.3561 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0487 | 0.1315 | 0.3657 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.