Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | glycosyl hydrolase, putative | 0.0154 | 0.2117 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0318 | 1 | 1 |
Onchocerca volvulus | 0.0318 | 1 | 0.5 | |
Onchocerca volvulus | 0.0318 | 1 | 0.5 | |
Loa Loa (eye worm) | trehalase | 0.0318 | 1 | 1 |
Brugia malayi | Trehalase family protein | 0.0318 | 1 | 1 |
Mycobacterium leprae | Possible hydrolase | 0.0154 | 0.2117 | 0.5 |
Brugia malayi | Trehalase family protein | 0.0318 | 1 | 1 |
Onchocerca volvulus | Trehalase homolog | 0.0318 | 1 | 0.5 |
Leishmania major | glycosyl hydrolase, putative | 0.0154 | 0.2117 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0318 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0318 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0318 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0318 | 1 | 1 |
Onchocerca volvulus | 0.0318 | 1 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0318 | 1 | 1 |
Brugia malayi | Trehalase family protein | 0.0318 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0318 | 1 | 1 |
Loa Loa (eye worm) | trehalase | 0.0318 | 1 | 1 |
Loa Loa (eye worm) | trehalase | 0.0318 | 1 | 1 |
Loa Loa (eye worm) | TRE-1 protein | 0.0318 | 1 | 1 |
Loa Loa (eye worm) | TRE-2 protein | 0.0318 | 1 | 1 |
Onchocerca volvulus | 0.0318 | 1 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0208 | 0.47 | 0.47 |
Mycobacterium ulcerans | glycosyl hydrolase | 0.0154 | 0.2117 | 0.5 |
Mycobacterium tuberculosis | Conserved protein | 0.0154 | 0.2117 | 0.5 |
Onchocerca volvulus | 0.0318 | 1 | 0.5 | |
Treponema pallidum | hypothetical protein | 0.011 | 0 | 0.5 |
Trypanosoma cruzi | glycosyl hydrolase, putative | 0.0154 | 0.2117 | 0.5 |
Trichomonas vaginalis | trehalase, putative | 0.0318 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.