Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0482 | 0.0482 |
Schistosoma mansoni | lipoxygenase | 0.0031 | 0.0804 | 0.0804 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.0042 | 0.1229 | 0.1229 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1229 | 0.1229 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.0042 | 0.1229 | 0.1229 |
Onchocerca volvulus | 0.0023 | 0.0482 | 0.1309 | |
Brugia malayi | hypothetical protein | 0.002 | 0.0357 | 0.0969 |
Schistosoma mansoni | nAChR subunit | 0.0042 | 0.1229 | 0.1229 |
Mycobacterium tuberculosis | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA | 0.0064 | 0.2038 | 0.5 |
Brugia malayi | Acetylcholine receptor protein, alpha-like chain 1 precursor | 0.002 | 0.0357 | 0.0969 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0357 | 0.0357 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1229 | 0.1229 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0042 | 0.1229 | 0.3339 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0107 | 0.3681 | 0.3681 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0023 | 0.0482 | 0.1309 |
Brugia malayi | Cation transporter family protein | 0.0075 | 0.2455 | 0.6669 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0357 | 0.0357 |
Schistosoma mansoni | nAChR subunit | 0.002 | 0.0357 | 0.0357 |
Schistosoma mansoni | nAChR subunit | 0.0042 | 0.1229 | 0.1229 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0482 | 0.0482 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0042 | 0.1229 | 0.1229 |
Loa Loa (eye worm) | ACC-1 protein | 0.0042 | 0.1229 | 0.1229 |
Schistosoma mansoni | acetylcholine receptor subunit beta | 0.002 | 0.0357 | 0.0357 |
Echinococcus multilocularis | nAChR subunit | 0.0023 | 0.0482 | 0.0482 |
Schistosoma mansoni | nAChR subunit | 0.0042 | 0.1229 | 0.1229 |
Echinococcus multilocularis | geminin | 0.0071 | 0.2316 | 0.2316 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0482 | 0.0482 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0042 | 0.1229 | 0.1229 |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.0042 | 0.1229 | 0.1229 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1229 | 0.1229 |
Schistosoma mansoni | lipoxygenase | 0.0045 | 0.1317 | 0.1317 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0016 | 0.0227 | 0.5 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0042 | 0.1229 | 0.3339 |
Giardia lamblia | DNA repair protein RAD52 | 0.0146 | 0.5163 | 1 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0107 | 0.3681 | 0.3681 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.0042 | 0.1229 | 0.3339 |
Loa Loa (eye worm) | neuronal acetylcholine receptor protein | 0.002 | 0.0357 | 0.0357 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0042 | 0.1229 | 0.1229 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0023 | 0.0482 | 0.0482 |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.0042 | 0.1229 | 0.3339 |
Brugia malayi | hypothetical protein | 0.002 | 0.0357 | 0.0969 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0482 | 0.0615 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1229 | 0.1229 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0042 | 0.1229 | 0.3339 |
Mycobacterium ulcerans | hypothetical protein | 0.0064 | 0.2038 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1229 | 0.1229 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0357 | 0.0357 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0482 | 0.0482 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0042 | 0.1229 | 0.1229 |
Loa Loa (eye worm) | GABA receptor subunit | 0.0023 | 0.0482 | 0.0482 |
Trichomonas vaginalis | acetylornithine aminotransferase, putative | 0.0064 | 0.2038 | 1 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0042 | 0.1229 | 0.1229 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.002 | 0.0357 | 0.0357 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1229 | 0.1229 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0482 | 0.0482 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0075 | 0.2455 | 0.2455 |
Onchocerca volvulus | 0.002 | 0.0357 | 0.0969 | |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.0042 | 0.1229 | 0.1229 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0042 | 0.1229 | 0.1229 |
Brugia malayi | hypothetical protein | 0.002 | 0.0357 | 0.0969 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0016 | 0.0227 | 0.5 |
Echinococcus granulosus | nAChR subunit | 0.0042 | 0.1229 | 0.1229 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0042 | 0.1229 | 0.3339 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0357 | 0.0357 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0107 | 0.3681 | 0.3681 |
Echinococcus granulosus | nAChR subunit | 0.0023 | 0.0482 | 0.0482 |
Schistosoma mansoni | nAChR subunit | 0.0042 | 0.1229 | 0.1229 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0107 | 0.3681 | 0.3681 |
Entamoeba histolytica | Rad52/22 family double-strand break repair protein, putative | 0.0041 | 0.1189 | 0.2034 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0357 | 0.0357 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.002 | 0.0357 | 0.0969 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.1708 | 0.1708 |
Brugia malayi | Cation transporter family protein | 0.0042 | 0.1229 | 0.3339 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.002 | 0.0357 | 0.0357 |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.0042 | 0.1229 | 0.1229 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0042 | 0.1229 | 0.1229 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1229 | 0.1229 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0107 | 0.3681 | 0.3681 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.0042 | 0.1229 | 0.3339 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0357 | 0.0357 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1229 | 0.1229 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0016 | 0.0227 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1229 | 0.1229 |
Schistosoma mansoni | nAChR subunit | 0.0042 | 0.1229 | 0.1229 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.2316 | 0.2316 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0042 | 0.1229 | 0.3339 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0042 | 0.1229 | 0.3339 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.3681 | 0.3681 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.0042 | 0.1229 | 0.3339 |
Onchocerca volvulus | 0.0075 | 0.2455 | 0.6669 | |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1229 | 0.1229 |
Loa Loa (eye worm) | ACC-1 protein | 0.0042 | 0.1229 | 0.1229 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0357 | 0.0357 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.002 | 0.0357 | 0.0969 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0482 | 0.0482 |
Brugia malayi | hypothetical protein | 0.002 | 0.0357 | 0.0969 |
Schistosoma mansoni | nAChR subunit | 0.0042 | 0.1229 | 0.1229 |
Schistosoma mansoni | nicotinic acetylcholine receptor alpha | 0.0023 | 0.0482 | 0.0482 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.002 | 0.0357 | 0.0357 |
Onchocerca volvulus | 0.002 | 0.0357 | 0.0969 | |
Echinococcus granulosus | geminin | 0.0071 | 0.2316 | 0.2316 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.0042 | 0.1229 | 0.1229 |
Loa Loa (eye worm) | LGC-31 protein | 0.0042 | 0.1229 | 0.1229 |
Onchocerca volvulus | 0.002 | 0.0357 | 0.0969 | |
Loa Loa (eye worm) | acetyltransferase | 0.0055 | 0.1709 | 0.1709 |
Schistosoma mansoni | hypothetical protein | 0.0273 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.2455 | 0.2455 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1229 | 0.1229 |
Mycobacterium tuberculosis | Probable aminotransferase | 0.0064 | 0.2038 | 0.5 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0042 | 0.1229 | 0.1229 |
Mycobacterium leprae | PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA | 0.0064 | 0.2038 | 0.5 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0198 | 0.7148 | 0.7148 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0055 | 0.1709 | 0.1709 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0042 | 0.1229 | 0.3339 |
Onchocerca volvulus | 0.0042 | 0.1229 | 0.3339 | |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit type | 0.002 | 0.0357 | 0.0357 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0107 | 0.3681 | 0.3681 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0042 | 0.1229 | 0.1229 |
Brugia malayi | glutamate-gated chloride channel alpha3A subunit, putative | 0.0023 | 0.0482 | 0.1309 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0042 | 0.1229 | 0.1229 |
Onchocerca volvulus | Putative nachr subunit | 0.0107 | 0.3681 | 1 |
Schistosoma mansoni | acetylcholine receptor-related | 0.002 | 0.0357 | 0.0357 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0042 | 0.1229 | 0.1229 |
Echinococcus granulosus | gamma aminobutyric acid receptor subunit | 0.002 | 0.0357 | 0.0357 |
Echinococcus multilocularis | small conductance calcium activated potassium | 0.0273 | 1 | 1 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0107 | 0.3681 | 0.3681 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0273 | 1 | 1 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.0042 | 0.1229 | 0.1229 |
Loa Loa (eye worm) | acetylcholine receptor protein | 0.002 | 0.0357 | 0.0357 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0015 | 0.0175 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0357 | 0.0357 |
Schistosoma mansoni | nAChR subunit | 0.002 | 0.0357 | 0.0357 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.0042 | 0.1229 | 0.1229 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0042 | 0.1229 | 0.1229 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.2455 | 0.2455 |
Brugia malayi | hypothetical protein | 0.002 | 0.0357 | 0.0969 |
Echinococcus multilocularis | nAChR subunit | 0.0042 | 0.1229 | 0.1229 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0357 | 0.0357 |
Brugia malayi | Neuronal acetylcholine receptor protein, alpha-2 chain precursor | 0.002 | 0.0357 | 0.0969 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0357 | 0.0357 |
Schistosoma mansoni | nAChR subunit | 0.0042 | 0.1229 | 0.1229 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0075 | 0.2455 | 0.2455 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0107 | 0.3681 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0482 | 0.0482 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.3582 | 0.3582 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0357 | 0.0357 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0042 | 0.1229 | 0.1229 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0357 | 0.0357 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0088 | 0.2964 | 0.2964 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0045 | 0.1317 | 0.1317 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1229 | 0.1229 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0482 | 0.0482 |
Echinococcus multilocularis | gamma aminobutyric acid receptor subunit | 0.002 | 0.0357 | 0.0357 |
Loa Loa (eye worm) | hypothetical protein | 0.0273 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1229 | 0.1229 |
Brugia malayi | follicle stimulating hormone receptor | 0.0088 | 0.2964 | 0.8051 |
Onchocerca volvulus | 0.0075 | 0.2455 | 0.6669 | |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0055 | 0.1709 | 0.4641 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0023 | 0.0482 | 0.0482 |
Mycobacterium ulcerans | adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 0.0064 | 0.2038 | 0.5 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0042 | 0.1229 | 0.1229 |
Onchocerca volvulus | 0.0042 | 0.1229 | 0.3339 | |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0054 | 0.165 | 0.165 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0357 | 0.0357 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.3175 | 0.3175 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.002 | 0.0357 | 0.0969 |
Onchocerca volvulus | 0.0075 | 0.2455 | 0.6669 | |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0045 | 0.1317 | 0.1317 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0042 | 0.1229 | 0.1229 |
Onchocerca volvulus | 0.0042 | 0.1229 | 0.3339 | |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.0042 | 0.1229 | 0.3339 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.0042 | 0.1229 | 0.1229 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0042 | 0.1229 | 0.1229 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.0042 | 0.1229 | 0.1229 |
Entamoeba histolytica | DNA repair and recombination protein RAD52, putative | 0.0146 | 0.5163 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0023 | 0.0482 | 0.1309 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.1189 | 0.2034 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0357 | 0.0357 |
Onchocerca volvulus | 0.0023 | 0.0482 | 0.1309 | |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.002 | 0.0357 | 0.0357 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0042 | 0.1229 | 0.3339 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0042 | 0.1229 | 0.3339 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.2075 | 0.2075 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0042 | 0.1229 | 0.3339 |
Brugia malayi | glutamate-gated chloride channel alpha3A subunit, putative | 0.002 | 0.0357 | 0.0969 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1229 | 0.1229 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.0042 | 0.1229 | 0.1229 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0023 | 0.0482 | 0.1309 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0055 | 0.1709 | 0.1709 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1229 | 0.1229 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0357 | 0.0357 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0016 | 0.0227 | 0.0227 |
Brugia malayi | Cation transporter family protein | 0.0042 | 0.1229 | 0.3339 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.0042 | 0.1229 | 0.1229 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1229 | 0.1229 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.2316 | 0.2316 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.002 | 0.0357 | 0.0357 |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.0042 | 0.1229 | 0.3339 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.