Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | arginine N-methyltransferase protein, putative | 0.0024 | 0.0316 | 0.5 |
Brugia malayi | Pre-SET motif family protein | 0.0302 | 0.8737 | 1 |
Trypanosoma brucei | S-adenosylmethionine decarboxylase proenzyme, putative | 0.0038 | 0.0744 | 1 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0043 | 0.0908 | 0.4689 |
Leishmania major | S-adenosylmethionine decarboxylase | 0.0038 | 0.0744 | 1 |
Plasmodium falciparum | protein arginine N-methyltransferase 1 | 0.0015 | 0.0057 | 0.3667 |
Trypanosoma cruzi | S-adenosylmethionine decarboxylase proenzyme, putative | 0.0038 | 0.0744 | 1 |
Schistosoma mansoni | protein arginine N-methyltransferase 1 | 0.0015 | 0.0057 | 0.0295 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.3758 | 0.4301 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0288 | 0.0329 |
Brugia malayi | S-adenosylmethionine decarboxylase proenzyme | 0.0038 | 0.0744 | 0.0852 |
Trypanosoma brucei | S-adenosylmethionine decarboxylase | 0.0038 | 0.0744 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0043 | 0.0908 | 0.4689 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0016 | 0.0085 | 0.0437 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0043 | 0.0908 | 0.4689 |
Echinococcus multilocularis | geminin | 0.0077 | 0.1937 | 1 |
Brugia malayi | NNMT/PNMT/TEMT family protein | 0.0137 | 0.3758 | 0.4301 |
Schistosoma mansoni | protein arginine N-methyltransferase 1 | 0.0015 | 0.0057 | 0.0295 |
Schistosoma mansoni | hypothetical protein | 0.0077 | 0.1937 | 1 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0016 | 0.0085 | 0.0437 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0302 | 0.8737 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0016 | 0.0085 | 0.0437 |
Plasmodium falciparum | S-adenosylmethionine decarboxylase/ornithine decarboxylase | 0.0018 | 0.0156 | 1 |
Trypanosoma brucei | S-adenosylmethionine decarboxylase | 0.0038 | 0.0744 | 1 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0016 | 0.0085 | 0.0437 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0043 | 0.0908 | 1 |
Loa Loa (eye worm) | NNMT/PNMT/TEMT family protein | 0.0137 | 0.3758 | 0.4301 |
Brugia malayi | jmjC domain containing protein | 0.0016 | 0.0085 | 0.0097 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0043 | 0.0908 | 0.4689 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0908 | 0.104 |
Schistosoma mansoni | hypothetical protein | 0.0077 | 0.1937 | 1 |
Echinococcus granulosus | S adenosylmethionine decarboxylase proenzyme | 0.0038 | 0.0744 | 0.3841 |
Plasmodium vivax | S-adenosylmethionine decarboxylase-ornithine decarboxylase, putative | 0.0018 | 0.0156 | 0.1716 |
Schistosoma mansoni | hypothetical protein | 0.0026 | 0.0377 | 0.1946 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0043 | 0.0908 | 0.4689 |
Onchocerca volvulus | 0.0043 | 0.0908 | 0.0908 | |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0043 | 0.0908 | 0.4689 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0042 | 0.086 | 0.444 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0316 | 0.0362 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0027 | 0.0429 | 0.0491 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0016 | 0.0085 | 0.0097 |
Trichomonas vaginalis | set domain proteins, putative | 0.0344 | 1 | 1 |
Schistosoma mansoni | jumonji domain containing protein | 0.0035 | 0.0645 | 0.3329 |
Echinococcus multilocularis | protein arginine N methyltransferase 8 | 0.0015 | 0.0057 | 0.0295 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0019 | 0.0158 | 0.0814 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0043 | 0.0908 | 0.4689 |
Echinococcus granulosus | geminin | 0.0077 | 0.1937 | 1 |
Plasmodium vivax | SET domain protein, putative | 0.0043 | 0.0908 | 1 |
Echinococcus granulosus | jumonji domain containing protein | 0.0019 | 0.0158 | 0.0814 |
Echinococcus granulosus | protein arginine N methyltransferase 8 | 0.0015 | 0.0057 | 0.0295 |
Echinococcus multilocularis | protein arginine methyltransferase | 0.0015 | 0.0057 | 0.0295 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0316 | 0.0362 |
Echinococcus granulosus | protein arginine methyltransferase | 0.0015 | 0.0057 | 0.0295 |
Schistosoma mansoni | protein arginine N-methyltransferase 1 | 0.0015 | 0.0057 | 0.0295 |
Giardia lamblia | PHD finger protein 15 | 0.0013 | 0 | 0.5 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0044 | 0.0916 | 0.4728 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.3758 | 0.4301 |
Echinococcus multilocularis | S adenosylmethionine decarboxylase proenzyme | 0.0038 | 0.0744 | 0.3841 |
Plasmodium vivax | protein arginine N-methyltransferase 1, putative | 0.0015 | 0.0057 | 0.0629 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0044 | 0.0916 | 0.4728 |
Brugia malayi | jmjC domain containing protein | 0.0044 | 0.0916 | 0.1048 |
Brugia malayi | Pre-SET motif family protein | 0.0043 | 0.0908 | 0.104 |
Trypanosoma cruzi | S-adenosylmethionine decarboxylase proenzyme, putative | 0.0038 | 0.0744 | 1 |
Toxoplasma gondii | histone arginine methyltransferase PRMT1 | 0.0015 | 0.0057 | 0.0629 |
Entamoeba histolytica | hypothetical protein | 0.0024 | 0.0316 | 0.5 |
Loa Loa (eye worm) | S-adenosylmethionine decarboxylase proenzyme | 0.0038 | 0.0744 | 0.0852 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.