Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0031 | 0.2903 | 0.8641 |
Echinococcus multilocularis | musashi | 0.0033 | 0.3359 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0031 | 0.2903 | 0.8641 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.2903 | 0.8641 |
Brugia malayi | intermediate filament protein | 0.0033 | 0.3359 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0031 | 0.2903 | 0.8641 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0031 | 0.2903 | 0.8641 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0031 | 0.2903 | 0.8641 |
Brugia malayi | nuclear receptor NHR-88 | 0.0031 | 0.2903 | 0.8641 |
Echinococcus granulosus | lamin dm0 | 0.0033 | 0.3359 | 1 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0033 | 0.3359 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0031 | 0.2903 | 0.8641 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0031 | 0.2903 | 0.8641 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0031 | 0.2903 | 0.8641 |
Brugia malayi | steroid hormone receptor | 0.0031 | 0.2903 | 0.8641 |
Onchocerca volvulus | 0.0033 | 0.3359 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.2903 | 0.8641 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.2903 | 0.8641 |
Echinococcus multilocularis | lamin dm0 | 0.0033 | 0.3359 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.3227 | 0.9606 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.2903 | 0.8641 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.2903 | 0.8641 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0031 | 0.2903 | 0.8641 |
Brugia malayi | ecdysteroid receptor | 0.0031 | 0.2903 | 0.8641 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0031 | 0.2903 | 0.8641 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.2903 | 0.8641 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0031 | 0.2903 | 0.8641 |
Echinococcus granulosus | lamin | 0.0033 | 0.3359 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0031 | 0.2903 | 0.8641 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.2903 | 0.8641 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0031 | 0.2903 | 0.8641 |
Schistosoma mansoni | lamin | 0.0033 | 0.3359 | 0.0643 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.3359 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0031 | 0.2903 | 0.8641 |
Schistosoma mansoni | intermediate filament proteins | 0.0033 | 0.3359 | 0.0643 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0031 | 0.2903 | 0.8641 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0031 | 0.2903 | 0.8641 |
Loa Loa (eye worm) | intermediate filament protein | 0.0033 | 0.3359 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.2903 | 0.8641 |
Onchocerca volvulus | 0.0033 | 0.3359 | 1 | |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0033 | 0.3359 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0031 | 0.2903 | 0.8641 |
Schistosoma mansoni | lamin | 0.0033 | 0.3359 | 0.0643 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0031 | 0.2903 | 0.8641 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0031 | 0.2903 | 0.8641 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0031 | 0.2903 | 0.8641 |
Echinococcus multilocularis | lamin | 0.0033 | 0.3359 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0031 | 0.2903 | 0.8641 |
Echinococcus granulosus | intermediate filament protein | 0.0033 | 0.3359 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0031 | 0.2903 | 0.8641 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0031 | 0.2903 | 0.8641 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0031 | 0.2903 | 0.8641 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0031 | 0.2903 | 0.8641 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.