Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | protein arginine N methyltransferase 8 | 0.0037 | 0.0089 | 0.0295 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0045 | 0.0245 | 0.0814 |
Echinococcus multilocularis | geminin | 0.0188 | 0.3009 | 1 |
Trypanosoma brucei | S-adenosylmethionine decarboxylase proenzyme, putative | 0.0092 | 0.1156 | 1 |
Plasmodium falciparum | S-adenosylmethionine decarboxylase/ornithine decarboxylase | 0.0045 | 0.0242 | 1 |
Echinococcus granulosus | S adenosylmethionine decarboxylase proenzyme | 0.0092 | 0.1156 | 0.3841 |
Echinococcus multilocularis | protein arginine methyltransferase | 0.0037 | 0.0089 | 0.0295 |
Trichomonas vaginalis | set domain proteins, putative | 0.055 | 1 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0067 | 0.0666 | 0.0764 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0067 | 0.0665 | 0.2208 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0039 | 0.0132 | 0.0437 |
Entamoeba histolytica | arginine N-methyltransferase protein, putative | 0.0058 | 0.0491 | 0.5 |
Brugia malayi | S-adenosylmethionine decarboxylase proenzyme | 0.0092 | 0.1156 | 0.1327 |
Onchocerca volvulus | 0.0069 | 0.0714 | 0.0714 | |
Trypanosoma cruzi | S-adenosylmethionine decarboxylase proenzyme, putative | 0.0092 | 0.1156 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0334 | 0.5836 | 0.6701 |
Brugia malayi | jmjC domain containing protein | 0.0106 | 0.1423 | 0.1633 |
Giardia lamblia | PHD finger protein 15 | 0.0032 | 0 | 0.5 |
Echinococcus granulosus | protein arginine methyltransferase | 0.0037 | 0.0089 | 0.0295 |
Schistosoma mansoni | protein arginine N-methyltransferase 1 | 0.0037 | 0.0089 | 0.0295 |
Echinococcus multilocularis | protein arginine N methyltransferase 8 | 0.0037 | 0.0089 | 0.0295 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0491 | 0.0564 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0069 | 0.0714 | 0.2372 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0106 | 0.1423 | 0.4728 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0069 | 0.0714 | 0.2372 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0106 | 0.1423 | 0.4728 |
Plasmodium vivax | protein arginine N-methyltransferase 1, putative | 0.0037 | 0.0089 | 0.1244 |
Plasmodium vivax | SET domain protein, putative | 0.0069 | 0.0714 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0069 | 0.0714 | 0.2372 |
Entamoeba histolytica | hypothetical protein | 0.0058 | 0.0491 | 0.5 |
Toxoplasma gondii | histone arginine methyltransferase PRMT1 | 0.0037 | 0.0089 | 0.1244 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0069 | 0.0714 | 0.2372 |
Loa Loa (eye worm) | hypothetical protein | 0.0334 | 0.5836 | 0.6701 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0447 | 0.0513 |
Brugia malayi | Pre-SET motif family protein | 0.0069 | 0.0714 | 0.0819 |
Schistosoma mansoni | protein arginine N-methyltransferase 1 | 0.0037 | 0.0089 | 0.0295 |
Plasmodium falciparum | protein arginine N-methyltransferase 1 | 0.0037 | 0.0089 | 0.3667 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0069 | 0.0714 | 0.2372 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0483 | 0.871 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0069 | 0.0714 | 0.2372 |
Leishmania major | S-adenosylmethionine decarboxylase | 0.0092 | 0.1156 | 1 |
Brugia malayi | hypothetical protein | 0.0058 | 0.0491 | 0.0564 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0039 | 0.0132 | 0.0437 |
Echinococcus granulosus | geminin | 0.0188 | 0.3009 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0483 | 0.871 | 1 |
Brugia malayi | NNMT/PNMT/TEMT family protein | 0.0334 | 0.5836 | 0.6701 |
Schistosoma mansoni | protein arginine N-methyltransferase 1 | 0.0037 | 0.0089 | 0.0295 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0039 | 0.0132 | 0.0437 |
Echinococcus multilocularis | S adenosylmethionine decarboxylase proenzyme | 0.0092 | 0.1156 | 0.3841 |
Schistosoma mansoni | hypothetical protein | 0.0188 | 0.3009 | 1 |
Trypanosoma cruzi | S-adenosylmethionine decarboxylase proenzyme, putative | 0.0092 | 0.1156 | 1 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0069 | 0.0714 | 0.2372 |
Trypanosoma brucei | S-adenosylmethionine decarboxylase | 0.0092 | 0.1156 | 1 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0039 | 0.0132 | 0.0437 |
Schistosoma mansoni | jumonji domain containing protein | 0.0084 | 0.1002 | 0.3329 |
Loa Loa (eye worm) | NNMT/PNMT/TEMT family protein | 0.0334 | 0.5836 | 0.6701 |
Brugia malayi | jmjC domain containing protein | 0.0039 | 0.0132 | 0.0151 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0069 | 0.0714 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0039 | 0.0132 | 0.0151 |
Plasmodium vivax | S-adenosylmethionine decarboxylase-ornithine decarboxylase, putative | 0.0045 | 0.0242 | 0.3392 |
Loa Loa (eye worm) | S-adenosylmethionine decarboxylase proenzyme | 0.0092 | 0.1156 | 0.1327 |
Schistosoma mansoni | hypothetical protein | 0.0063 | 0.0585 | 0.1946 |
Echinococcus granulosus | jumonji domain containing protein | 0.0045 | 0.0245 | 0.0814 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0714 | 0.0819 |
Schistosoma mansoni | hypothetical protein | 0.0188 | 0.3009 | 1 |
Trypanosoma brucei | S-adenosylmethionine decarboxylase | 0.0092 | 0.1156 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.