Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | farnesyltransferase beta subunit | 0.049 | 0.1904 | 0.7831 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0037 | 0.0085 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Brugia malayi | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Brugia malayi | Melatonin receptor type 1A | 0.008 | 0.0256 | 0.0238 |
Onchocerca volvulus | 0.008 | 0.0256 | 0.1021 | |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0037 | 0.0085 | 0.0067 |
Echinococcus multilocularis | g protein coupled receptor | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | geranylgeranyl transferase type I beta subunit | 0.2508 | 1 | 1 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.008 | 0.0256 | 0.0239 |
Toxoplasma gondii | hypothetical protein | 0.1593 | 0.6329 | 1 |
Echinococcus granulosus | fmrfamide receptor | 0.008 | 0.0256 | 0.0238 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.008 | 0.0256 | 0.0239 |
Brugia malayi | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Schistosoma mansoni | amine GPCR | 0.008 | 0.0256 | 0.0239 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.008 | 0.0256 | 0.0239 |
Trypanosoma cruzi | protein farnesyltransferase, putative | 0.049 | 0.1904 | 0.4309 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.008 | 0.0256 | 0.0238 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0719 | 0.2821 | 0.2809 |
Trypanosoma cruzi | protein farnesyltransferase alpha subunit, putative | 0.06 | 0.2344 | 1 |
Brugia malayi | neuropeptide F receptor | 0.008 | 0.0256 | 0.0238 |
Trypanosoma brucei | Protein prenyltransferase alpha subunit repeat, putative | 0.06 | 0.2344 | 1 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.008 | 0.0256 | 0.0238 |
Echinococcus granulosus | somatostatin receptor | 0.008 | 0.0256 | 0.0238 |
Giardia lamblia | Prenyltransferase | 0.049 | 0.1904 | 0.0465 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Schistosoma mansoni | amine GPCR | 0.008 | 0.0256 | 0.0239 |
Brugia malayi | protein-tyrosine kinase | 0.005 | 0.0139 | 0.0121 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.008 | 0.0256 | 0.0238 |
Toxoplasma gondii | Rab geranylgeranyl transferase type II beta subunit, putative | 0.0407 | 0.1571 | 0.2482 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Brugia malayi | Serotonin receptor | 0.008 | 0.0256 | 0.0238 |
Onchocerca volvulus | 0.008 | 0.0256 | 0.1021 | |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.008 | 0.0256 | 0.0238 |
Brugia malayi | Prenyltransferase and squalene oxidase repeat family protein | 0.049 | 0.1904 | 0.1889 |
Entamoeba histolytica | protein farnesyltransferase beta subunit, putative | 0.049 | 0.1904 | 0.1889 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.008 | 0.0256 | 0.0239 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.008 | 0.0256 | 0.0239 |
Schistosoma mansoni | hypothetical protein | 0.008 | 0.0256 | 0.0239 |
Echinococcus multilocularis | allatostatin A receptor | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.0057 | 0.0167 | 0.0149 |
Echinococcus granulosus | tyrosine kinase | 0.005 | 0.0139 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Brugia malayi | GnHR receptor homolog | 0.008 | 0.0256 | 0.0238 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0057 | 0.0166 | 0.0148 |
Brugia malayi | G-protein coupled receptor | 0.008 | 0.0256 | 0.0238 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.008 | 0.0256 | 0.0238 |
Brugia malayi | Dopamine receptor | 0.008 | 0.0256 | 0.0238 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.008 | 0.0256 | 0.0238 |
Onchocerca volvulus | 0.008 | 0.0256 | 0.1021 | |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0057 | 0.0166 | 0.0148 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.008 | 0.0256 | 0.0238 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.008 | 0.0256 | 0.1021 |
Schistosoma mansoni | tyrosine kinase | 0.0057 | 0.0166 | 0.0149 |
Schistosoma mansoni | geranylgeranyl transferase type II beta subunit | 0.0407 | 0.1571 | 0.1556 |
Plasmodium falciparum | protein farnesyltransferase subunit beta | 0.049 | 0.1904 | 0.2179 |
Schistosoma mansoni | hypothetical protein | 0.008 | 0.0256 | 0.0239 |
Schistosoma mansoni | neuropeptide receptor | 0.008 | 0.0256 | 0.0239 |
Toxoplasma gondii | prenyltransferase and squalene oxidase repeat-containing protein | 0.0407 | 0.1571 | 0.2482 |
Brugia malayi | SRC-1 | 0.0057 | 0.0166 | 0.0148 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0057 | 0.0166 | 0.0148 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0057 | 0.0166 | 0.0148 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | protein farnesyltransferase subunit beta | 0.049 | 0.1904 | 0.1889 |
Echinococcus multilocularis | fmrfamide receptor | 0.008 | 0.0256 | 0.0238 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.008 | 0.0256 | 0.0239 |
Entamoeba histolytica | protein farnesyltransferase alpha subunit, putative | 0.2193 | 0.8737 | 0.8734 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.008 | 0.0256 | 0.0238 |
Plasmodium falciparum | protein farnesyltransferase subunit alpha | 0.2193 | 0.8737 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.008 | 0.0256 | 0.0238 |
Brugia malayi | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative | 0.2193 | 0.8737 | 0.8501 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.06 | 0.2344 | 0.233 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase src | 0.0027 | 0.0046 | 0.0028 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Echinococcus granulosus | neuropeptide receptor | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | mitogen activated protein kinase kinase kinase | 0.0706 | 0.2769 | 0.2756 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.06 | 0.2344 | 1 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.008 | 0.0256 | 0.0238 |
Onchocerca volvulus | 0.008 | 0.0256 | 0.1021 | |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.008 | 0.0256 | 0.0238 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.008 | 0.0256 | 0.0238 |
Brugia malayi | ORL1-like opioid receptor | 0.008 | 0.0256 | 0.0238 |
Schistosoma mansoni | tyrosine kinase | 0.0226 | 0.0842 | 0.0826 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit, putative | 0.2193 | 0.8737 | 0.8501 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.008 | 0.0256 | 0.0238 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.008 | 0.0256 | 0.0238 |
Onchocerca volvulus | 0.008 | 0.0256 | 0.1021 | |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.008 | 0.0256 | 0.0238 |
Trypanosoma brucei | hypothetical protein, conserved | 0.06 | 0.2344 | 1 |
Echinococcus multilocularis | c src tyrosine kinase | 0.0027 | 0.0046 | 0.0027 |
Onchocerca volvulus | 0.008 | 0.0256 | 0.1021 | |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.0057 | 0.0166 | 0.0148 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.008 | 0.0256 | 0.0238 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Echinococcus granulosus | g-protein coupled receptor | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Trypanosoma brucei | Protein prenyltransferase alpha subunit repeat, putative | 0.06 | 0.2344 | 1 |
Brugia malayi | Dopamine receptor protein 2 | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | orexin receptor type 2 | 0.008 | 0.0256 | 0.0238 |
Onchocerca volvulus | 0.008 | 0.0256 | 0.1021 | |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Schistosoma mansoni | neuropeptide receptor | 0.008 | 0.0256 | 0.0239 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Giardia lamblia | Rab geranylgeranyltransferase | 0.2193 | 0.8737 | 1 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.008 | 0.0256 | 0.0238 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.008 | 0.0256 | 0.0239 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.008 | 0.0256 | 0.0238 |
Trypanosoma cruzi | lanosterol synthase, putative | 0.0501 | 0.1948 | 0.4884 |
Brugia malayi | G protein-coupled receptor | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Onchocerca volvulus | 0.008 | 0.0256 | 0.1021 | |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.0057 | 0.0166 | 0.0148 |
Brugia malayi | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Schistosoma mansoni | adenoreceptor | 0.008 | 0.0256 | 0.0239 |
Echinococcus multilocularis | tyrosine protein kinase Btk29A | 0.0027 | 0.0046 | 0.0027 |
Loa Loa (eye worm) | prenyltransferase alpha subunit repeat containing protein | 0.2193 | 0.8737 | 0.8734 |
Onchocerca volvulus | 0.008 | 0.0256 | 0.1021 | |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.008 | 0.0256 | 0.0238 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.008 | 0.0256 | 0.0238 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.008 | 0.0256 | 0.0239 |
Loa Loa (eye worm) | prenyltransferase and squalene oxidase repeat family protein | 0.049 | 0.1904 | 0.1889 |
Plasmodium vivax | protein prenyltransferase alpha subunit, putative | 0.06 | 0.2344 | 0.2683 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.0316 | 0.0298 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | tyrosine protein kinase Abl | 0.0108 | 0.0371 | 0.0354 |
Echinococcus granulosus | protein farnesyltransferase alpha subunit | 0.2193 | 0.8737 | 0.8734 |
Brugia malayi | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Brugia malayi | Protein kinase domain containing protein | 0.0706 | 0.2769 | 0.2756 |
Echinococcus granulosus | tyrosine protein kinase HCK | 0.0043 | 0.0111 | 0.0093 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Echinococcus granulosus | protein prenyltransferase alpha subunit | 0.06 | 0.2344 | 0.233 |
Echinococcus multilocularis | g protein coupled receptor | 0.008 | 0.0256 | 0.0238 |
Onchocerca volvulus | 0.008 | 0.0256 | 0.1021 | |
Schistosoma mansoni | tyrosine kinase | 0.002 | 0.0018 | 0.0001 |
Echinococcus granulosus | serotonin receptor | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.0705 | 0.2768 | 0.2754 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Trypanosoma brucei | lanosterol synthase | 0.0501 | 0.1948 | 0.4884 |
Trichomonas vaginalis | geranylgeranyl transferase type beta subunit, putative | 0.049 | 0.1904 | 0.0395 |
Schistosoma mansoni | opsin-like receptor | 0.008 | 0.0256 | 0.0239 |
Onchocerca volvulus | 0.008 | 0.0256 | 0.1021 | |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.008 | 0.0256 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.008 | 0.0256 | 0.0239 |
Schistosoma mansoni | tyrosine kinase | 0.0027 | 0.0046 | 0.0028 |
Plasmodium vivax | farnesyltransferase beta subunit, putative | 0.049 | 0.1904 | 0.2179 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.008 | 0.0256 | 0.0238 |
Echinococcus granulosus | g protein coupled receptor | 0.008 | 0.0256 | 0.0238 |
Onchocerca volvulus | 0.008 | 0.0256 | 0.1021 | |
Echinococcus granulosus | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.008 | 0.0256 | 0.0238 |
Brugia malayi | putative neuropeptide receptor | 0.008 | 0.0256 | 0.0238 |
Onchocerca volvulus | 0.008 | 0.0256 | 0.1021 | |
Echinococcus granulosus | neuropeptide s receptor | 0.008 | 0.0256 | 0.0238 |
Trypanosoma brucei | protein farnesyltransferase beta subunit | 0.049 | 0.1904 | 0.4309 |
Loa Loa (eye worm) | SRC-1 | 0.0057 | 0.0166 | 0.0148 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.008 | 0.0256 | 0.0238 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.008 | 0.0256 | 0.1021 |
Echinococcus multilocularis | g-protein coupled receptor | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.008 | 0.0256 | 0.0238 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.008 | 0.0256 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.0407 | 0.1571 | 0.1555 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Plasmodium falciparum | geranylgeranyl transferase type-2 subunit alpha, putative | 0.06 | 0.2344 | 0.2683 |
Schistosoma mansoni | amine GPCR | 0.008 | 0.0256 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Brugia malayi | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Plasmodium vivax | conserved Plasmodium protein, unknown function | 0.0083 | 0.027 | 0.0309 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.008 | 0.0256 | 0.0239 |
Echinococcus granulosus | g protein coupled receptor | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.008 | 0.0256 | 0.0238 |
Trypanosoma cruzi | lanosterol synthase, putative | 0.0501 | 0.1948 | 0.4884 |
Trichomonas vaginalis | geranylgeranyl transferase type II beta subunit, putative | 0.049 | 0.1904 | 0.0395 |
Schistosoma mansoni | protein farnesyltransferase subunit beta | 0.049 | 0.1904 | 0.189 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.008 | 0.0256 | 0.0239 |
Entamoeba histolytica | geranylgeranyl transferase beta subunit | 0.2508 | 1 | 1 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.008 | 0.0256 | 0.0238 |
Brugia malayi | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Schistosoma mansoni | hypothetical protein | 0.008 | 0.0256 | 0.0239 |
Echinococcus granulosus | protein farnesyltransferase subunit beta | 0.049 | 0.1904 | 0.1889 |
Brugia malayi | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.008 | 0.0256 | 0.0238 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative | 0.1593 | 0.6329 | 0.5645 |
Trypanosoma brucei | protein farnesyltransferase alpha subunit, putative | 0.06 | 0.2344 | 1 |
Echinococcus multilocularis | fmrfamide receptor | 0.008 | 0.0256 | 0.0238 |
Giardia lamblia | Rab geranylgeranyltransferase | 0.06 | 0.2344 | 0.1079 |
Echinococcus granulosus | orexin receptor type 2 | 0.008 | 0.0256 | 0.0238 |
Trypanosoma cruzi | protein farnesyltransferase, putative | 0.049 | 0.1904 | 0.4309 |
Trichomonas vaginalis | geranylgeranyl transferase type II beta subunit, putative | 0.049 | 0.1904 | 0.0395 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.008 | 0.0256 | 0.0238 |
Trypanosoma cruzi | protein farnesyltransferase alpha subunit, putative | 0.06 | 0.2344 | 1 |
Onchocerca volvulus | 0.008 | 0.0256 | 0.1021 | |
Echinococcus multilocularis | neuropeptide Y receptor | 0.008 | 0.0256 | 0.0238 |
Plasmodium vivax | prenyltransferase alpha subunit, putative | 0.2193 | 0.8737 | 1 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.008 | 0.0256 | 0.0238 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.008 | 0.0256 | 0.0239 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.008 | 0.0256 | 0.0238 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0108 | 0.0371 | 0.0354 |
Schistosoma mansoni | myosin xvIII | 0.008 | 0.0256 | 0.0239 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.008 | 0.0256 | 0.0238 |
Onchocerca volvulus | 0.008 | 0.0256 | 0.1021 | |
Echinococcus multilocularis | geranylgeranyl transferase type 2 subunit alpha | 0.06 | 0.2344 | 0.233 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | tyrosine protein kinase HCK | 0.0043 | 0.0111 | 0.0093 |
Echinococcus granulosus | tyrosine kinase|tyrosine protein kinase Fyn | 0.005 | 0.0139 | 0.0121 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.008 | 0.0256 | 0.0239 |
Schistosoma mansoni | tyrosine kinase | 0.002 | 0.0018 | 0.0001 |
Echinococcus multilocularis | protein prenyltransferase alpha subunit | 0.06 | 0.2344 | 0.233 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.008 | 0.0256 | 0.0239 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.008 | 0.0256 | 0.0239 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.008 | 0.0256 | 0.0239 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.2193 | 0.8737 | 0.8734 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.008 | 0.0256 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Brugia malayi | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Onchocerca volvulus | 0.008 | 0.0256 | 0.1021 | |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit, putative | 0.2193 | 0.8737 | 0.8501 |
Brugia malayi | neuropeptide F receptor | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | prenyltransferase and squalene oxidase repeat family protein | 0.2508 | 1 | 1 |
Toxoplasma gondii | prenyltransferase and squalene oxidase repeat-containing protein | 0.049 | 0.1904 | 0.3008 |
Schistosoma mansoni | biogenic amine receptor | 0.008 | 0.0256 | 0.0239 |
Echinococcus multilocularis | protein farnesyltransferase alpha subunit | 0.2193 | 0.8737 | 0.8734 |
Echinococcus granulosus | geranylgeranyl transferase type I beta subunit | 0.2508 | 1 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.008 | 0.0256 | 0.0238 |
Brugia malayi | G-protein coupled receptor | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | g protein coupled receptor | 0.008 | 0.0256 | 0.0238 |
Echinococcus granulosus | tyrosine protein kinase Blk | 0.005 | 0.0139 | 0.0121 |
Onchocerca volvulus | 0.06 | 0.2344 | 1 | |
Echinococcus multilocularis | neuropeptides capa receptor | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.0057 | 0.0166 | 0.0148 |
Leishmania major | protein farnesyltransferase alpha subunit, putative | 0.06 | 0.2344 | 1 |
Echinococcus granulosus | neuropeptides capa receptor | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0057 | 0.0166 | 0.0148 |
Schistosoma mansoni | geranylgeranyl transferase type I beta subunit | 0.2508 | 1 | 1 |
Trypanosoma cruzi | Protein prenyltransferase alpha subunit repeat, putative | 0.06 | 0.2344 | 1 |
Echinococcus granulosus | mitogen activated protein kinase kinase kinase | 0.0706 | 0.2769 | 0.2756 |
Brugia malayi | Probable protein farnesyltransferase beta subunit, putative | 0.0407 | 0.1571 | 0.1555 |
Trichomonas vaginalis | geranylgeranyl transferase type I beta subunit, putative | 0.2508 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.06 | 0.2344 | 1 |
Brugia malayi | Protein prenyltransferase alpha subunit repeat containing protein | 0.06 | 0.2344 | 0.233 |
Echinococcus granulosus | sex peptide receptor | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | TK protein kinase | 0.0043 | 0.0111 | 0.0093 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.008 | 0.0256 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.0705 | 0.2768 | 0.2754 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.0057 | 0.0166 | 0.0148 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.008 | 0.0256 | 0.0238 |
Schistosoma mansoni | biogenic amine receptor | 0.008 | 0.0256 | 0.0239 |
Onchocerca volvulus | 0.008 | 0.0256 | 0.1021 | |
Plasmodium vivax | geranylgeranyl transferase type2 beta subunit, putative | 0.0407 | 0.1571 | 0.1798 |
Echinococcus multilocularis | serotonin receptor | 0.008 | 0.0256 | 0.0238 |
Leishmania major | geranylgeranyltransferase, putative | 0.0407 | 0.1571 | 0.6189 |
Schistosoma mansoni | hypothetical protein | 0.008 | 0.0256 | 0.0239 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.008 | 0.0256 | 0.0238 |
Brugia malayi | AKH receptor | 0.008 | 0.0256 | 0.0238 |
Brugia malayi | RE15519p | 0.008 | 0.0256 | 0.0238 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.008 | 0.0256 | 0.0238 |
Brugia malayi | larval opioid receptor | 0.008 | 0.0256 | 0.0238 |
Echinococcus granulosus | neuropeptide Y receptor | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | somatostatin receptor | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | neuropeptide receptor | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.008 | 0.0256 | 0.0238 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.008 | 0.0256 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.008 | 0.0256 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Schistosoma mansoni | neuropeptide receptor | 0.008 | 0.0256 | 0.0239 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.008 | 0.0256 | 0.0239 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0057 | 0.0166 | 0.0148 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.008 | 0.0256 | 0.0239 |
Echinococcus granulosus | neuropeptide receptor | 0.008 | 0.0256 | 0.0238 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0131 | 0.0463 | 0.0445 |
Plasmodium vivax | geranylgeranyltransferase, putative | 0.0407 | 0.1571 | 0.1798 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.008 | 0.0256 | 0.0238 |
Plasmodium falciparum | geranylgeranyl transferase type2 beta subunit, putative | 0.0407 | 0.1571 | 0.1798 |
Loa Loa (eye worm) | TKL/MLK/LZK protein kinase | 0.0706 | 0.2769 | 0.2756 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.008 | 0.0256 | 0.0239 |
Echinococcus multilocularis | serotonin receptor | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.0407 | 0.1571 | 0.1555 |
Entamoeba histolytica | Rab geranylgeranyltransferase alpha subunit, putative | 0.06 | 0.2344 | 0.233 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.0057 | 0.0166 | 0.0148 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.008 | 0.0256 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | tyrosine protein kinase Srms | 0.005 | 0.0139 | 0.0121 |
Echinococcus granulosus | neuropeptides capa receptor | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.008 | 0.0256 | 0.0238 |
Trichomonas vaginalis | geranylgeranyl transferase type I beta subunit, putative | 0.049 | 0.1904 | 0.0395 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0057 | 0.0166 | 0.0148 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | sex peptide receptor | 0.008 | 0.0256 | 0.0238 |
Echinococcus granulosus | allatostatin A receptor | 0.008 | 0.0256 | 0.0238 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.008 | 0.0256 | 0.0239 |
Brugia malayi | sulfakinin receptor protein | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.008 | 0.0256 | 0.0238 |
Schistosoma mansoni | amine GPCR | 0.008 | 0.0256 | 0.0239 |
Plasmodium falciparum | geranylgeranyltransferase, putative | 0.0407 | 0.1571 | 0.1798 |
Echinococcus granulosus | c src tyrosine kinase | 0.0027 | 0.0046 | 0.0027 |
Echinococcus multilocularis | tyrosine protein kinase ABL1 | 0.0233 | 0.087 | 0.0853 |
Echinococcus multilocularis | Rab geranylgeranyltransferase, beta subunit | 0.0407 | 0.1571 | 0.1555 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.008 | 0.0256 | 0.0238 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | TK protein kinase | 0.005 | 0.0139 | 0.0121 |
Schistosoma mansoni | histamine h1 receptor | 0.008 | 0.0256 | 0.0239 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Schistosoma mansoni | tyrosine kinase | 0.0057 | 0.0166 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Schistosoma mansoni | protein farnesyltransferase alpha subunit | 0.2193 | 0.8737 | 0.8734 |
Brugia malayi | Serotonin receptor | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | TYRA-2 protein | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.0057 | 0.0166 | 0.0148 |
Schistosoma mansoni | tyrosine kinase | 0.0027 | 0.0046 | 0.0028 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.008 | 0.0256 | 0.0238 |
Echinococcus granulosus | neuropeptide Y receptor | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.008 | 0.0256 | 0.0238 |
Trichomonas vaginalis | type I geranylgeranyltransferase beta subunit, putative | 0.049 | 0.1904 | 0.0395 |
Echinococcus multilocularis | tyrosine protein kinase Blk | 0.005 | 0.0139 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0057 | 0.0166 | 0.0148 |
Schistosoma mansoni | neuropeptide receptor | 0.008 | 0.0256 | 0.0239 |
Loa Loa (eye worm) | TK/ABL protein kinase | 0.0233 | 0.087 | 0.0853 |
Entamoeba histolytica | protein kinase, putative | 0.0043 | 0.0111 | 0.0093 |
Toxoplasma gondii | hypothetical protein | 0.06 | 0.2344 | 0.3704 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.008 | 0.0256 | 0.0238 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.0057 | 0.0166 | 0.0148 |
Echinococcus granulosus | tyrosine protein kinase ABL1 | 0.0233 | 0.087 | 0.0853 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.008 | 0.0256 | 0.0239 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Entamoeba histolytica | Rab geranylgeranyltransferase beta subunit, putative | 0.0407 | 0.1571 | 0.1555 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.008 | 0.0256 | 0.0238 |
Schistosoma mansoni | amine GPCR | 0.008 | 0.0256 | 0.0239 |
Loa Loa (eye worm) | prenyltransferase alpha subunit repeat containing protein | 0.06 | 0.2344 | 0.233 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.005 | 0.0139 | 0.0121 |
Brugia malayi | follicle stimulating hormone receptor | 0.008 | 0.0256 | 0.0238 |
Brugia malayi | Dopamine receptor protein 1 | 0.008 | 0.0256 | 0.0238 |
Brugia malayi | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0256 | 0.0238 |
Schistosoma mansoni | opsin-like receptor | 0.008 | 0.0256 | 0.0239 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit, putative | 0.06 | 0.2344 | 0.0918 |
Echinococcus granulosus | g protein coupled receptor | 0.008 | 0.0256 | 0.0238 |
Schistosoma mansoni | opsin-like receptor | 0.008 | 0.0256 | 0.0239 |
Mycobacterium tuberculosis | Halimadienyl diphosphate synthase | 0.0501 | 0.1948 | 0.5 |
Trichomonas vaginalis | geranylgeranyl transferase type II beta subunit, putative | 0.049 | 0.1904 | 0.0395 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.0057 | 0.0166 | 0.0148 |
Echinococcus multilocularis | neuropeptide receptor | 0.008 | 0.0256 | 0.0238 |
Schistosoma mansoni | geranylgeranyl transferase type I beta subunit | 0.2508 | 1 | 1 |
Brugia malayi | Protein prenyltransferase alpha subunit repeat containing protein | 0.2193 | 0.8737 | 0.8734 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.008 | 0.0256 | 0.0238 |
Echinococcus multilocularis | neuropeptide s receptor | 0.008 | 0.0256 | 0.0238 |
Echinococcus granulosus | geranylgeranyl transferase type 2 subunit alpha | 0.06 | 0.2344 | 0.233 |
Schistosoma mansoni | biogenic amine receptor | 0.008 | 0.0256 | 0.0239 |
Echinococcus granulosus | tyrosine protein kinase Btk29A | 0.0027 | 0.0046 | 0.0027 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.008 | 0.0256 | 0.0239 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Kd (binding) | = 144 nM | Displacement of [3H]-clonidine from alpha2-adrenergic receptor of calf neocortical membrane | ChEMBL. | 6298426 |
Kd (binding) | = 380 nM | Displacement of [3H]-prazosin from alpha1-adrenergic receptor of calf neocortical membrane | ChEMBL. | 6298426 |
Ratio (binding) | = 2.6 | Relative affinity for alpha-1 and alpha-2 adrenergic receptors | ChEMBL. | 6298426 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.