Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | nAChR subunit | 0.0429 | 0.0731 | 0.1366 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0826 | 0.1904 | 0.356 |
Brugia malayi | Cation transporter family protein | 0.0826 | 0.1904 | 0.1768 |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.2823 | 0.7814 | 1 |
Onchocerca volvulus | 0.0429 | 0.0731 | 0.0758 | |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.0826 | 0.1904 | 0.1355 |
Loa Loa (eye worm) | glyceraldehyde 3-phosphate dehydrogenase | 0.1286 | 0.3267 | 0.2811 |
Toxoplasma gondii | glyceraldehyde-3-phosphate dehydrogenase GAPDH2 | 0.199 | 0.5348 | 1 |
Brugia malayi | glyceraldehyde 3-phosphate dehydrogenase | 0.0632 | 0.1331 | 0.097 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.199 | 0.5348 | 1 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0826 | 0.1904 | 0.356 |
Echinococcus granulosus | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1286 | 0.3267 | 0.4531 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0826 | 0.1904 | 0.356 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Trypanosoma brucei | acetyl-CoA carboxylase | 0.0478 | 0.0876 | 0.1638 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit type | 0.0397 | 0.0634 | 0.1186 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Chlamydia trachomatis | glyceraldehyde-3-phosphate dehydrogenase | 0.199 | 0.5348 | 0.5 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Schistosoma mansoni | acetylcholine receptor subunit beta | 0.0397 | 0.0634 | 0.1186 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.0826 | 0.1904 | 0.1355 |
Loa Loa (eye worm) | glyceraldehyde 3-phosphate dehydrogenase | 0.1286 | 0.3267 | 0.2811 |
Wolbachia endosymbiont of Brugia malayi | glyceraldehyde-3-phosphate dehydrogenase, GapA | 0.199 | 0.5348 | 1 |
Brugia malayi | Carboxyl transferase domain containing protein | 0.0461 | 0.0826 | 0.0267 |
Loa Loa (eye worm) | hypothetical protein | 0.2427 | 0.6641 | 0.6413 |
Echinococcus granulosus | gamma aminobutyric acid receptor subunit | 0.0397 | 0.0634 | 0.1186 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Echinococcus multilocularis | acetyl coenzyme A carboxylase 1 | 0.0478 | 0.0876 | 0.1638 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.199 | 0.5348 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | hypothetical protein | 0.1286 | 0.3267 | 0.2811 |
Loa Loa (eye worm) | LGC-31 protein | 0.0826 | 0.1904 | 0.1355 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.0826 | 0.1904 | 0.1768 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | glyceraldehyde-3-phosphate dehydrogenase | 0.1358 | 0.3478 | 0.3036 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.199 | 0.5348 | 1 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1286 | 0.3267 | 0.4531 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, cytosolic | 0.199 | 0.5348 | 1 |
Onchocerca volvulus | 0.0826 | 0.1904 | 1 | |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.0826 | 0.1904 | 0.1768 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | carboxyl transferase domain-containing protein | 0.0461 | 0.0826 | 0.0205 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | ACC-1 protein | 0.0826 | 0.1904 | 0.1355 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0826 | 0.1904 | 0.356 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.0826 | 0.1904 | 0.356 |
Giardia lamblia | Glyceraldehyde 3-phosphate dehydrogenase | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Schistosoma mansoni | nAChR subunit | 0.0397 | 0.0634 | 0.1186 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0826 | 0.1904 | 0.1768 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0826 | 0.1904 | 0.1355 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0632 | 0.1331 | 0.2489 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.199 | 0.5348 | 1 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0826 | 0.1904 | 0.356 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0826 | 0.1904 | 0.356 |
Toxoplasma gondii | acetyl-CoA carboxylase ACC1 | 0.0478 | 0.0876 | 0.1638 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Schistosoma mansoni | acetyl-CoA carboxylase | 0.0478 | 0.0876 | 0.1638 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0826 | 0.1904 | 0.1768 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.199 | 0.5348 | 1 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative | 0.0632 | 0.1331 | 0.2489 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Echinococcus multilocularis | nAChR subunit | 0.0429 | 0.0731 | 0.1366 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0429 | 0.0731 | 0.1366 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0429 | 0.0731 | 0.0134 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0826 | 0.1904 | 0.1768 |
Onchocerca volvulus | 0.0826 | 0.1904 | 1 | |
Leishmania major | acetyl-CoA carboxylase, putative | 0.0478 | 0.0876 | 0.1638 |
Mycobacterium ulcerans | glyceraldehyde 3-phosphate dehydrogenase Gap | 0.199 | 0.5348 | 1 |
Trypanosoma cruzi | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.1847 | 0.4926 | 0.921 |
Onchocerca volvulus | Putative nachr subunit | 0.0826 | 0.1904 | 1 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0429 | 0.0731 | 0.0134 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.0623 | 0.1303 | 0.933 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.0826 | 0.1904 | 0.356 |
Trypanosoma cruzi | acetyl-CoA carboxylase | 0.0296 | 0.0337 | 0.063 |
Brugia malayi | Glyceraldehyde 3-phosphate dehydrogenase | 0.0703 | 0.1542 | 0.1265 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.067 | 0.1443 | 0.2698 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.199 | 0.5348 | 1 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0826 | 0.1904 | 0.356 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.199 | 0.5348 | 1 |
Echinococcus multilocularis | gamma aminobutyric acid receptor subunit | 0.0397 | 0.0634 | 0.1186 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Echinococcus granulosus | acetyl coenzyme A carboxylase 1 | 0.0478 | 0.0876 | 0.1638 |
Plasmodium vivax | tryptophan-rich antigen (Pv-fam-a) | 0.1827 | 0.4867 | 0.9012 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0826 | 0.1904 | 0.356 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Trypanosoma cruzi | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.1847 | 0.4926 | 0.921 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.1286 | 0.3267 | 0.6108 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.0826 | 0.1904 | 0.1355 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.0826 | 0.1904 | 0.356 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0429 | 0.0731 | 0.1366 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.199 | 0.5348 | 1 |
Leishmania major | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0826 | 0.1904 | 0.356 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0826 | 0.1904 | 0.1768 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.1286 | 0.3267 | 0.6108 |
Onchocerca volvulus | 0.0826 | 0.1904 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0397 | 0.0634 | 0.1186 |
Echinococcus multilocularis | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Loa Loa (eye worm) | ACC-1 protein | 0.0826 | 0.1904 | 0.1355 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Onchocerca volvulus | 0.0826 | 0.1904 | 1 | |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Brugia malayi | glutamate-gated chloride channel alpha3A subunit, putative | 0.0429 | 0.0731 | 0.0134 |
Onchocerca volvulus | 0.0826 | 0.1904 | 1 | |
Toxoplasma gondii | acetyl-coA carboxylase ACC2 | 0.0478 | 0.0876 | 0.1638 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Leishmania major | glyceraldehyde-3-phosphate dehydrogenase-like protein | 0.1847 | 0.4926 | 0.921 |
Mycobacterium tuberculosis | Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) | 0.0654 | 0.1397 | 1 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0397 | 0.0634 | 0.1186 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.0826 | 0.1904 | 0.356 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.199 | 0.5348 | 1 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative | 0.0632 | 0.1331 | 0.2489 |
Brugia malayi | Glyceraldehyde 3-phosphate dehydrogenase | 0.199 | 0.5348 | 0.6565 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0826 | 0.1904 | 0.356 |
Trypanosoma brucei | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.1847 | 0.4926 | 0.921 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.067 | 0.1443 | 0.2698 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0429 | 0.0731 | 0.0134 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0826 | 0.1904 | 0.356 |
Brugia malayi | Cation transporter family protein | 0.0826 | 0.1904 | 0.1768 |
Schistosoma mansoni | acetylcholine receptor-related | 0.0397 | 0.0634 | 0.1186 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.0826 | 0.1904 | 0.356 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | GABA receptor subunit | 0.0429 | 0.0731 | 0.0103 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0826 | 0.1904 | 0.1355 |
Plasmodium vivax | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Onchocerca volvulus | 0.0826 | 0.1904 | 1 | |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.0826 | 0.1904 | 0.1768 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.0826 | 0.1904 | 0.1355 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0826 | 0.1904 | 0.1768 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0826 | 0.1904 | 0.356 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0397 | 0.0634 | 0.1186 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Onchocerca volvulus | 0.0429 | 0.0731 | 0.0758 | |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Mycobacterium leprae | Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) | 0.0654 | 0.1397 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0826 | 0.1904 | 0.356 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.0826 | 0.1904 | 0.1768 |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.0826 | 0.1904 | 0.356 |
Schistosoma mansoni | nAChR subunit | 0.0397 | 0.0634 | 0.1186 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Toxoplasma gondii | glyceraldehyde-3-phosphate dehydrogenase GAPDH1 | 0.199 | 0.5348 | 1 |
Treponema pallidum | glyceraldehyde 3-phosphate dehydrogenase (gap) | 0.199 | 0.5348 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.0826 | 0.1904 | 0.356 |
Plasmodium falciparum | glyceraldehyde-3-phosphate dehydrogenase | 0.199 | 0.5348 | 1 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2823 | 0.7814 | 0.7666 |
Leishmania major | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.199 | 0.5348 | 1 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0826 | 0.1904 | 0.356 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0632 | 0.1331 | 0.2489 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.0826 | 0.1904 | 0.1768 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0826 | 0.1904 | 0.1768 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0826 | 0.1904 | 0.356 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Brugia malayi | Cation transporter family protein | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | glyceraldehyde-3-phosphate dehydrogenase | 0.1358 | 0.3478 | 0.3036 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0397 | 0.0634 | 0.1186 |
Schistosoma mansoni | nicotinic acetylcholine receptor alpha | 0.0429 | 0.0731 | 0.1366 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0632 | 0.1331 | 0.2489 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0826 | 0.1904 | 0.1768 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | < 10 % | The ability of the compound to inhibit platelet aggregation was tested; <10 | ChEMBL. | 3373489 |
Reduction (functional) | = -25 % | Hypolipidemic activity of the compound was expressed as percent decrease in triglycerides in Sprague-Dawley rats | ChEMBL. | 3373489 |
Reduction (functional) | = -4 % | Hypolipidemic activity of the compound was expressed as percent decrease in serum cholesterol in Sprague-Dawley rats | ChEMBL. | 3373489 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.