TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 359.804 | Formula: C19H18ClNO4
H donors: 0 H acceptors: 2 LogP: 4.51 Rotable bonds: 6
Rule of 5 violations (Lipinski): 1
SMILES: CCOC(=O)C(c1nc(oc1c1ccco1)c1ccc(cc1)Cl)(C)C
InChi: 1S/C19H18ClNO4/c1-4-23-18(22)19(2,3)16-15(14-6-5-11-24-14)25-17(21-16)12-7-9-13(20)10-8-12/h5-11H,4H2,1-3H3
InChiKey: CVEIVWSWEUGQTL-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trypanosoma cruzi	glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative	0.199	0.5348	1
Loa Loa (eye worm)	hypothetical protein	0.1286	0.3267	0.2811
Chlamydia trachomatis	glyceraldehyde-3-phosphate dehydrogenase	0.199	0.5348	0.5
Echinococcus multilocularis	glycine receptor subunit alpha 1	0.0826	0.1904	0.356
Echinococcus granulosus	glycine receptor subunit alpha 1	0.0826	0.1904	0.356
Loa Loa (eye worm)	hypothetical protein	0.2427	0.6641	0.6413
Trypanosoma cruzi	glyceraldehyde 3-phosphate dehydrogenase, putative	0.199	0.5348	1
Trypanosoma cruzi	glyceraldehyde 3-phosphate dehydrogenase, putative	0.199	0.5348	1
Echinococcus granulosus	acetyl coenzyme A carboxylase 1	0.0478	0.0876	0.1638
Echinococcus multilocularis	acetyl coenzyme A carboxylase 1	0.0478	0.0876	0.1638
Loa Loa (eye worm)	hypothetical protein	0.0826	0.1904	0.1355
Loa Loa (eye worm)	hypothetical protein	0.0826	0.1904	0.1355
Schistosoma mansoni	nAChR subunit	0.0397	0.0634	0.1186
Loa Loa (eye worm)	hypothetical protein	0.0429	0.0731	0.0103
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0826	0.1904	0.1768
Schistosoma mansoni	glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)	0.199	0.5348	1
Loa Loa (eye worm)	hypothetical protein	0.0826	0.1904	0.1355
Loa Loa (eye worm)	hypothetical protein	0.0826	0.1904	0.1355
Loa Loa (eye worm)	hypothetical protein	0.0826	0.1904	0.1355
Schistosoma mansoni	acetylcholine receptor subunit beta	0.0397	0.0634	0.1186
Brugia malayi	glyceraldehyde 3-phosphate dehydrogenase	0.0632	0.1331	0.097
Brugia malayi	Cation transporter family protein	0.0826	0.1904	0.1768
Loa Loa (eye worm)	carboxyl transferase domain-containing protein	0.0461	0.0826	0.0205
Brugia malayi	Carboxyl transferase domain containing protein	0.0461	0.0826	0.0267
Trypanosoma cruzi	glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative	0.0632	0.1331	0.2489
Loa Loa (eye worm)	hypothetical protein	0.0826	0.1904	0.1355
Trypanosoma cruzi	glyceraldehyde 3-phosphate dehydrogenase, putative	0.199	0.5348	1
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0826	0.1904	0.1768
Trypanosoma brucei	acetyl-CoA carboxylase	0.0478	0.0876	0.1638
Schistosoma mansoni	nAChR subunit	0.0826	0.1904	0.356
Loa Loa (eye worm)	hypothetical protein	0.0826	0.1904	0.1355
Loa Loa (eye worm)	hypothetical protein	0.0826	0.1904	0.1355
Mycobacterium ulcerans	flavin-containing monoamine oxidase AofH	0.067	0.1443	0.2698
Trypanosoma cruzi	glyceraldehyde-3-phosphate dehydrogenase, putative	0.1847	0.4926	0.921
Onchocerca volvulus		0.0826	0.1904	1
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0826	0.1904	0.356
Echinococcus multilocularis	glyceraldehyde 3 phosphate dehydrogenase	0.199	0.5348	1
Trypanosoma cruzi	glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative	0.199	0.5348	1
Loa Loa (eye worm)	hypothetical protein	0.0826	0.1904	0.1355
Loa Loa (eye worm)	excitatory GABA receptor EXP-1A	0.0826	0.1904	0.1355
Echinococcus multilocularis	acetylcholine receptor subunit beta 1	0.0826	0.1904	0.356
Echinococcus multilocularis	Cys loop ligand gated ion channel subunit	0.0397	0.0634	0.1186
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0826	0.1904	0.1768
Loa Loa (eye worm)	hypothetical protein	0.0826	0.1904	0.1355
Trypanosoma cruzi	glyceraldehyde-3-phosphate dehydrogenase, putative	0.1847	0.4926	0.921
Echinococcus multilocularis	nicotinic acetylcholine receptor subunit alpha 8	0.0826	0.1904	0.356
Loa Loa (eye worm)	nicotinic acetylcholine receptor alpha subunit	0.0826	0.1904	0.1355
Toxoplasma gondii	glyceraldehyde-3-phosphate dehydrogenase GAPDH1	0.199	0.5348	1
Schistosoma mansoni	glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)	0.199	0.5348	1
Loa Loa (eye worm)	hypothetical protein	0.0429	0.0731	0.0103
Loa Loa (eye worm)	hypothetical protein	0.0429	0.0731	0.0103
Brugia malayi	Glyceraldehyde 3-phosphate dehydrogenase	0.0703	0.1542	0.1265
Loa Loa (eye worm)	hypothetical protein	0.0826	0.1904	0.1355
Echinococcus multilocularis	nAChR subunit	0.0429	0.0731	0.1366
Loa Loa (eye worm)	glyceraldehyde 3-phosphate dehydrogenase	0.1286	0.3267	0.2811
Brugia malayi	Cation transporter family protein	0.0826	0.1904	0.1768
Echinococcus multilocularis	nicotinic acetylcholine receptor beta 1 subunit	0.0826	0.1904	0.356
Echinococcus multilocularis	neuronal acetylcholine receptor subunit alpha 4	0.0826	0.1904	0.356
Echinococcus multilocularis	nAChR subunit	0.0826	0.1904	0.356
Brugia malayi	acetylcholine receptor alpha subunit precursor, putative	0.0826	0.1904	0.1768
Trypanosoma cruzi	glyceraldehyde 3-phosphate dehydrogenase, putative	0.199	0.5348	1
Echinococcus multilocularis	glyceraldehyde 3 phosphate dehydrogenase	0.1286	0.3267	0.6108
Echinococcus multilocularis	glyceraldehyde 3 phosphate dehydrogenase	0.199	0.5348	1
Brugia malayi	acetylcholine receptor protein, alpha-like chain, putative	0.0826	0.1904	0.1768
Trichomonas vaginalis	glyceraldehyde 3-phosphate dehydrogenase, putative	0.199	0.5348	1
Loa Loa (eye worm)	hypothetical protein	0.0826	0.1904	0.1355
Loa Loa (eye worm)	hypothetical protein	0.2823	0.7814	0.7666
Trichomonas vaginalis	glyceraldehyde 3-phosphate dehydrogenase, putative	0.1286	0.3267	0.4531
Brugia malayi	acetylcholine receptor, alpha-type subunit unc-38 precursor	0.0826	0.1904	0.1768
Echinococcus granulosus	Cys loop ligand gated ion channel subunit	0.0397	0.0634	0.1186
Trypanosoma cruzi	acetyl-CoA carboxylase	0.0296	0.0337	0.063
Echinococcus multilocularis	glycine receptor subunit alpha 1	0.0826	0.1904	0.356
Loa Loa (eye worm)	nicotinic acetylcholine receptor non-alpha subunit	0.0826	0.1904	0.1355
Echinococcus multilocularis	nicotinic acetylcholine receptor a11 subunit	0.0826	0.1904	0.356
Leishmania major	glyceraldehyde 3-phosphate dehydrogenase, glycosomal	0.199	0.5348	1
Loa Loa (eye worm)	glutamate-gated chloride channel alpha3A subunit	0.0826	0.1904	0.1355
Brugia malayi	Cation transporter family protein	0.0826	0.1904	0.1768
Schistosoma mansoni	nAChR subunit	0.0826	0.1904	0.356
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0826	0.1904	0.1768
Echinococcus granulosus	nAChR subunit	0.0826	0.1904	0.356
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0429	0.0731	0.0134
Schistosoma mansoni	acetyl-CoA carboxylase	0.0478	0.0876	0.1638
Echinococcus granulosus	gamma aminobutyric acid receptor subunit	0.0397	0.0634	0.1186
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0826	0.1904	0.1768
Onchocerca volvulus	Putative nachr subunit	0.0826	0.1904	1
Loa Loa (eye worm)	hypothetical protein	0.0826	0.1904	0.1355
Schistosoma mansoni	nicotinic acetylcholine receptor alpha	0.0429	0.0731	0.1366
Toxoplasma gondii	acetyl-coA carboxylase ACC2	0.0478	0.0876	0.1638
Onchocerca volvulus		0.0826	0.1904	1
Loa Loa (eye worm)	glyceraldehyde 3-phosphate dehydrogenase	0.1286	0.3267	0.2811
Schistosoma mansoni	acetylcholine receptor-related	0.0397	0.0634	0.1186
Loa Loa (eye worm)	hypothetical protein	0.0429	0.0731	0.0103
Entamoeba histolytica	glyceraldehyde-3-phosphate dehydrogenase, putative	0.199	0.5348	1
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0826	0.1904	0.1768
Schistosoma mansoni	nAChR subunit	0.0826	0.1904	0.356
Trypanosoma cruzi	glyceraldehyde 3-phosphate dehydrogenase, putative	0.0632	0.1331	0.2489
Loa Loa (eye worm)	hypothetical protein	0.0429	0.0731	0.0103
Plasmodium vivax	tryptophan-rich antigen (Pv-fam-a)	0.1827	0.4867	0.9012
Loa Loa (eye worm)	ACC-1 protein	0.0826	0.1904	0.1355
Echinococcus granulosus	glycine receptor subunit beta	0.0826	0.1904	0.356
Trichomonas vaginalis	glyceraldehyde 3-phosphate dehydrogenase, putative	0.199	0.5348	1
Treponema pallidum	glyceraldehyde 3-phosphate dehydrogenase (gap)	0.199	0.5348	0.5
Trypanosoma brucei	glyceraldehyde 3-phosphate dehydrogenase, cytosolic	0.199	0.5348	1
Echinococcus granulosus	acetylcholine receptor subunit beta 1	0.0826	0.1904	0.356
Echinococcus granulosus	nicotinic acetylcholine receptor beta 1 subunit	0.0826	0.1904	0.356
Onchocerca volvulus		0.0826	0.1904	1
Echinococcus multilocularis	glycine receptor subunit beta	0.0826	0.1904	0.356
Trichomonas vaginalis	glyceraldehyde 3-phosphate dehydrogenase, putative	0.199	0.5348	1
Mycobacterium tuberculosis	Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH)	0.0654	0.1397	1
Loa Loa (eye worm)	acetylcholine receptor alpha subunit	0.0826	0.1904	0.1355
Echinococcus multilocularis	glycine receptor subunit alpha 1	0.0826	0.1904	0.356
Schistosoma mansoni	neurotransmitter gated ion channel	0.0429	0.0731	0.1366
Echinococcus granulosus	nicotinic acetylcholine receptor a11 subunit	0.0826	0.1904	0.356
Mycobacterium ulcerans	flavin-containing monoamine oxidase AofH	0.067	0.1443	0.2698
Loa Loa (eye worm)	LGC-31 protein	0.0826	0.1904	0.1355
Plasmodium vivax	glyceraldehyde-3-phosphate dehydrogenase, putative	0.199	0.5348	1
Brugia malayi	glutamate-gated chloride channel alpha3A subunit, putative	0.0429	0.0731	0.0134
Leishmania major	acetyl-CoA carboxylase, putative	0.0478	0.0876	0.1638
Onchocerca volvulus		0.0429	0.0731	0.0758
Loa Loa (eye worm)	hypothetical protein	0.0826	0.1904	0.1355
Onchocerca volvulus		0.0429	0.0731	0.0758
Schistosoma mansoni	nAChR subunit (ShAR1-beta2-like)	0.0826	0.1904	0.356
Trypanosoma cruzi	glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative	0.0632	0.1331	0.2489
Echinococcus granulosus	glyceraldehyde 3 phosphate dehydrogenase	0.199	0.5348	1
Brugia malayi	Hypothetical glycine receptor like protein T20B12.9 in chromosome III	0.0429	0.0731	0.0134
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0826	0.1904	0.1768
Echinococcus granulosus	Cys loop ligand gated ion channel subunit	0.0826	0.1904	0.356
Schistosoma mansoni	neurotransmitter gated ion channel	0.0397	0.0634	0.1186
Loa Loa (eye worm)	hypothetical protein	0.0429	0.0731	0.0103
Loa Loa (eye worm)	hypothetical protein	0.0429	0.0731	0.0103
Schistosoma mansoni	nAChR subunit (ShAR1-beta-like)	0.0826	0.1904	0.356
Trypanosoma brucei	glyceraldehyde 3-phosphate dehydrogenase, glycosomal	0.199	0.5348	1
Loa Loa (eye worm)	hypothetical protein	0.0826	0.1904	0.1355
Echinococcus granulosus	nicotinic acetylcholine receptor subunit type	0.0826	0.1904	0.356
Trypanosoma brucei	glyceraldehyde 3-phosphate dehydrogenase, glycosomal	0.199	0.5348	1
Giardia lamblia	Glyceraldehyde 3-phosphate dehydrogenase	0.199	0.5348	1
Brugia malayi	nicotinic acetylcholine receptor alpha subunit, putative	0.0826	0.1904	0.1768
Echinococcus granulosus	nicotinic acetylcholine receptor subunit alpha 8	0.0826	0.1904	0.356
Toxoplasma gondii	acetyl-CoA carboxylase ACC1	0.0478	0.0876	0.1638
Onchocerca volvulus		0.0826	0.1904	1
Trypanosoma cruzi	glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative	0.199	0.5348	1
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0429	0.0731	0.1366
Loa Loa (eye worm)	ligand-Gated ion Channel family member	0.0826	0.1904	0.1355
Trypanosoma brucei	glyceraldehyde-3-phosphate dehydrogenase, putative	0.1847	0.4926	0.921
Echinococcus multilocularis	gamma aminobutyric acid receptor subunit	0.0397	0.0634	0.1186
Echinococcus granulosus	glyceraldehyde 3 phosphate dehydrogenase	0.1286	0.3267	0.6108
Loa Loa (eye worm)	hypothetical protein	0.0826	0.1904	0.1355
Brugia malayi	Glyceraldehyde 3-phosphate dehydrogenase	0.199	0.5348	0.6565
Entamoeba histolytica	glyceraldehyde-3-phosphate dehydrogenase, putative	0.199	0.5348	1
Trichomonas vaginalis	glyceraldehyde 3-phosphate dehydrogenase, putative	0.1286	0.3267	0.4531
Loa Loa (eye worm)	ACC-1 protein	0.0826	0.1904	0.1355
Mycobacterium leprae	Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH)	0.0654	0.1397	1
Loa Loa (eye worm)	hypothetical protein	0.0826	0.1904	0.1355
Loa Loa (eye worm)	hypothetical protein	0.0429	0.0731	0.0103
Schistosoma mansoni	nAChR subunit	0.0826	0.1904	0.356
Wolbachia endosymbiont of Brugia malayi	glyceraldehyde-3-phosphate dehydrogenase, GapA	0.199	0.5348	1
Echinococcus granulosus	glyceraldehyde 3 phosphate dehydrogenase	0.199	0.5348	1
Schistosoma mansoni	nAChR subunit	0.0826	0.1904	0.356
Brugia malayi	excitatory GABA receptor EXP-1A	0.0826	0.1904	0.1768
Brugia malayi	nicotinic acetylcholine receptor beta-1 chain precursor	0.0826	0.1904	0.1768
Schistosoma mansoni	nAChR subunit	0.0826	0.1904	0.356
Echinococcus granulosus	glycine receptor subunit alpha 1	0.0826	0.1904	0.356
Echinococcus multilocularis	nicotinic acetylcholine receptor alpha subunit	0.0826	0.1904	0.356
Trypanosoma cruzi	glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative	0.0632	0.1331	0.2489
Brugia malayi	gamma-aminobutyric-acid receptor beta subunit precursor	0.2823	0.7814	1
Mycobacterium tuberculosis	Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO)	0.0623	0.1303	0.933
Loa Loa (eye worm)	glyceraldehyde-3-phosphate dehydrogenase	0.1358	0.3478	0.3036
Echinococcus granulosus	neuronal acetylcholine receptor subunit alpha 4	0.0826	0.1904	0.356
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0826	0.1904	0.356
Brugia malayi	Hypothetical glycine receptor like protein T20B12.9 in chromosome III	0.0826	0.1904	0.1768
Echinococcus granulosus	nAChR subunit	0.0429	0.0731	0.1366
Schistosoma mansoni	neurotransmitter gated ion channel	0.0397	0.0634	0.1186
Mycobacterium ulcerans	glyceraldehyde 3-phosphate dehydrogenase Gap	0.199	0.5348	1
Onchocerca volvulus		0.0826	0.1904	1
Schistosoma mansoni	nAChR subunit	0.0826	0.1904	0.356
Toxoplasma gondii	glyceraldehyde-3-phosphate dehydrogenase GAPDH2	0.199	0.5348	1
Loa Loa (eye worm)	glyceraldehyde-3-phosphate dehydrogenase	0.1358	0.3478	0.3036
Schistosoma mansoni	glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)	0.199	0.5348	1
Echinococcus multilocularis	glycine receptor subunit beta	0.0826	0.1904	0.356
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0429	0.0731	0.0134
Trypanosoma cruzi	glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative	0.0632	0.1331	0.2489
Schistosoma mansoni	glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)	0.199	0.5348	1
Leishmania major	glyceraldehyde-3-phosphate dehydrogenase-like protein	0.1847	0.4926	0.921
Leishmania major	glyceraldehyde 3-phosphate dehydrogenase, glycosomal	0.199	0.5348	1
Echinococcus granulosus	glycine receptor subunit alpha 1	0.0826	0.1904	0.356
Plasmodium falciparum	glyceraldehyde-3-phosphate dehydrogenase	0.199	0.5348	1
Echinococcus multilocularis	Cys loop ligand gated ion channel subunit	0.0826	0.1904	0.356
Schistosoma mansoni	nAChR subunit (ShAR1-alpha-like)	0.0826	0.1904	0.356
Onchocerca volvulus		0.0826	0.1904	1
Entamoeba histolytica	glyceraldehyde-3-phosphate dehydrogenase, putative	0.199	0.5348	1
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0826	0.1904	0.1768
Echinococcus multilocularis	nicotinic acetylcholine receptor subunit type	0.0397	0.0634	0.1186
Trichomonas vaginalis	glyceraldehyde 3-phosphate dehydrogenase, putative	0.199	0.5348	1
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0826	0.1904	0.356
Echinococcus granulosus	glycine receptor subunit beta	0.0826	0.1904	0.356
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0826	0.1904	0.1768
Trichomonas vaginalis	glyceraldehyde 3-phosphate dehydrogenase, putative	0.199	0.5348	1
Echinococcus granulosus	nicotinic acetylcholine receptor alpha subunit	0.0826	0.1904	0.356
Loa Loa (eye worm)	GABA receptor subunit	0.0429	0.0731	0.0103
Schistosoma mansoni	nAChR subunit	0.0397	0.0634	0.1186

Activities

Activity type	Activity value	Assay description	Source	Reference
Inhibition (functional)	< 10 %	The ability of the compound to inhibit platelet aggregation was tested; <10	ChEMBL.	3373489
Reduction (functional)	= -25 %	Hypolipidemic activity of the compound was expressed as percent decrease in triglycerides in Sprague-Dawley rats	ChEMBL.	3373489
Reduction (functional)	= -4 %	Hypolipidemic activity of the compound was expressed as percent decrease in serum cholesterol in Sprague-Dawley rats	ChEMBL.	3373489

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL18736

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 21284