Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | casein kinase 1, epsilon | No references | |
Homo sapiens | casein kinase 1, delta | No references |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | casein kinase I alpha | 0.0092 | 1 | 0.5 |
Leishmania major | casein kinase, putative | 0.0092 | 1 | 0.5 |
Entamoeba histolytica | casein kinase, putative | 0.0092 | 1 | 0.5 |
Trypanosoma cruzi | casein kinase, putative | 0.0092 | 1 | 1 |
Entamoeba histolytica | casein kinase 1, putative | 0.0092 | 1 | 0.5 |
Echinococcus multilocularis | casein kinase I alpha | 0.0092 | 1 | 0.5 |
Schistosoma mansoni | protein kinase | 0.0092 | 1 | 0.5 |
Toxoplasma gondii | casein kinase I | 0.0092 | 1 | 0.5 |
Echinococcus granulosus | casein kinase I alpha | 0.0092 | 1 | 0.5 |
Plasmodium vivax | casein kinase 1, putative | 0.0092 | 1 | 0.5 |
Echinococcus granulosus | casein kinase I delta | 0.0092 | 1 | 0.5 |
Loa Loa (eye worm) | CK1/CK1/CK1-A protein kinase | 0.0092 | 1 | 0.5 |
Trichomonas vaginalis | CK1 family protein kinase | 0.0092 | 1 | 0.5 |
Loa Loa (eye worm) | CK1/CK1/CK1-D protein kinase | 0.0092 | 1 | 0.5 |
Onchocerca volvulus | 0.0092 | 1 | 1 | |
Trichomonas vaginalis | CK1 family protein kinase | 0.0092 | 1 | 0.5 |
Echinococcus multilocularis | casein kinase I alpha | 0.0092 | 1 | 0.5 |
Giardia lamblia | Kinase, CK1 Casein kinase | 0.0092 | 1 | 0.5 |
Echinococcus multilocularis | casein kinase I delta | 0.0092 | 1 | 0.5 |
Echinococcus granulosus | casein kinase i | 0.0092 | 1 | 0.5 |
Echinococcus granulosus | casein kinase I delta | 0.0092 | 1 | 0.5 |
Brugia malayi | casein kinase I | 0.0092 | 1 | 0.5 |
Trypanosoma cruzi | casein kinase, putative | 0.0092 | 1 | 1 |
Loa Loa (eye worm) | CK1/CK1/CK1-A protein kinase | 0.0092 | 1 | 0.5 |
Echinococcus multilocularis | casein kinase I delta | 0.0092 | 1 | 0.5 |
Trypanosoma cruzi | casein kinase, putative | 0.0092 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0092 | 1 | 0.5 |
Echinococcus multilocularis | casein kinase I alpha | 0.0092 | 1 | 0.5 |
Echinococcus multilocularis | casein kinase i | 0.0092 | 1 | 0.5 |
Trypanosoma cruzi | casein kinase, delta isoform, putative | 0.0092 | 1 | 1 |
Echinococcus granulosus | casein kinase I alpha | 0.0092 | 1 | 0.5 |
Trypanosoma brucei | casein kinase I, isoform 2 | 0.0092 | 1 | 0.5 |
Trichomonas vaginalis | CK1 family protein kinase | 0.0092 | 1 | 0.5 |
Plasmodium falciparum | casein kinase 1 | 0.0092 | 1 | 0.5 |
Trypanosoma cruzi | casein kinase, putative | 0.0092 | 1 | 1 |
Trypanosoma cruzi | casein kinase, putative | 0.0092 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 1.6 nM | Kinase Assay | BINDINGDB. | No reference |
IC50 (binding) | = 9.3 nM | Kinase Assay | BINDINGDB. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.