Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0632 | 0.1331 | 0.2489 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0826 | 0.1904 | 0.356 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Brugia malayi | Carboxyl transferase domain containing protein | 0.0461 | 0.0826 | 0.0267 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0826 | 0.1904 | 0.356 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative | 0.0632 | 0.1331 | 0.2489 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Trypanosoma cruzi | acetyl-CoA carboxylase | 0.0296 | 0.0337 | 0.063 |
Onchocerca volvulus | 0.0429 | 0.0731 | 0.0758 | |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.199 | 0.5348 | 1 |
Schistosoma mansoni | nicotinic acetylcholine receptor alpha | 0.0429 | 0.0731 | 0.1366 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | glyceraldehyde 3-phosphate dehydrogenase | 0.1286 | 0.3267 | 0.2811 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0826 | 0.1904 | 0.1355 |
Chlamydia trachomatis | glyceraldehyde-3-phosphate dehydrogenase | 0.199 | 0.5348 | 0.5 |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.0826 | 0.1904 | 0.1768 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0826 | 0.1904 | 0.1768 |
Plasmodium vivax | tryptophan-rich antigen (Pv-fam-a) | 0.1827 | 0.4867 | 0.9012 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Loa Loa (eye worm) | glyceraldehyde-3-phosphate dehydrogenase | 0.1358 | 0.3478 | 0.3036 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0826 | 0.1904 | 0.356 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.0623 | 0.1303 | 0.933 |
Brugia malayi | Cation transporter family protein | 0.0826 | 0.1904 | 0.1768 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0397 | 0.0634 | 0.1186 |
Mycobacterium ulcerans | glyceraldehyde 3-phosphate dehydrogenase Gap | 0.199 | 0.5348 | 1 |
Echinococcus multilocularis | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0429 | 0.0731 | 0.1366 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0429 | 0.0731 | 0.0134 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Toxoplasma gondii | acetyl-CoA carboxylase ACC1 | 0.0478 | 0.0876 | 0.1638 |
Onchocerca volvulus | 0.0826 | 0.1904 | 1 | |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0826 | 0.1904 | 0.356 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.0826 | 0.1904 | 0.356 |
Mycobacterium leprae | Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) | 0.0654 | 0.1397 | 1 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0397 | 0.0634 | 0.1186 |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.0826 | 0.1904 | 0.356 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0826 | 0.1904 | 0.1768 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit type | 0.0397 | 0.0634 | 0.1186 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Loa Loa (eye worm) | hypothetical protein | 0.2823 | 0.7814 | 0.7666 |
Onchocerca volvulus | Putative nachr subunit | 0.0826 | 0.1904 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0826 | 0.1904 | 0.1355 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.0826 | 0.1904 | 0.356 |
Plasmodium vivax | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Echinococcus granulosus | acetyl coenzyme A carboxylase 1 | 0.0478 | 0.0876 | 0.1638 |
Onchocerca volvulus | 0.0429 | 0.0731 | 0.0758 | |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.0826 | 0.1904 | 0.1355 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Onchocerca volvulus | 0.0826 | 0.1904 | 1 | |
Brugia malayi | Glyceraldehyde 3-phosphate dehydrogenase | 0.0703 | 0.1542 | 0.1265 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0826 | 0.1904 | 0.1768 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.199 | 0.5348 | 1 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0429 | 0.0731 | 0.0134 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.067 | 0.1443 | 0.2698 |
Leishmania major | glyceraldehyde-3-phosphate dehydrogenase-like protein | 0.1847 | 0.4926 | 0.921 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Brugia malayi | Glyceraldehyde 3-phosphate dehydrogenase | 0.199 | 0.5348 | 0.6565 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Schistosoma mansoni | acetyl-CoA carboxylase | 0.0478 | 0.0876 | 0.1638 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Schistosoma mansoni | nAChR subunit | 0.0397 | 0.0634 | 0.1186 |
Onchocerca volvulus | 0.0826 | 0.1904 | 1 | |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0826 | 0.1904 | 0.356 |
Brugia malayi | Cation transporter family protein | 0.0826 | 0.1904 | 0.1768 |
Schistosoma mansoni | acetylcholine receptor subunit beta | 0.0397 | 0.0634 | 0.1186 |
Giardia lamblia | Glyceraldehyde 3-phosphate dehydrogenase | 0.199 | 0.5348 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0826 | 0.1904 | 0.1768 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Loa Loa (eye worm) | GABA receptor subunit | 0.0429 | 0.0731 | 0.0103 |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.2823 | 0.7814 | 1 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.0826 | 0.1904 | 0.1355 |
Echinococcus multilocularis | gamma aminobutyric acid receptor subunit | 0.0397 | 0.0634 | 0.1186 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.1286 | 0.3267 | 0.6108 |
Brugia malayi | Cation transporter family protein | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | hypothetical protein | 0.2427 | 0.6641 | 0.6413 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1286 | 0.3267 | 0.4531 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.0826 | 0.1904 | 0.356 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0826 | 0.1904 | 0.356 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0397 | 0.0634 | 0.1186 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0826 | 0.1904 | 0.356 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | glyceraldehyde-3-phosphate dehydrogenase | 0.1358 | 0.3478 | 0.3036 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0826 | 0.1904 | 0.356 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, cytosolic | 0.199 | 0.5348 | 1 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0826 | 0.1904 | 0.1768 |
Echinococcus granulosus | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0826 | 0.1904 | 0.356 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0632 | 0.1331 | 0.2489 |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.0826 | 0.1904 | 0.1768 |
Plasmodium falciparum | glyceraldehyde-3-phosphate dehydrogenase | 0.199 | 0.5348 | 1 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.0826 | 0.1904 | 0.1355 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.0826 | 0.1904 | 0.1355 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.1286 | 0.3267 | 0.6108 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Loa Loa (eye worm) | LGC-31 protein | 0.0826 | 0.1904 | 0.1355 |
Leishmania major | acetyl-CoA carboxylase, putative | 0.0478 | 0.0876 | 0.1638 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0826 | 0.1904 | 0.356 |
Onchocerca volvulus | 0.0826 | 0.1904 | 1 | |
Schistosoma mansoni | nAChR subunit | 0.0397 | 0.0634 | 0.1186 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.199 | 0.5348 | 1 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.067 | 0.1443 | 0.2698 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.199 | 0.5348 | 1 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0826 | 0.1904 | 0.356 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.0826 | 0.1904 | 0.356 |
Onchocerca volvulus | 0.0826 | 0.1904 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.1286 | 0.3267 | 0.2811 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0826 | 0.1904 | 0.356 |
Echinococcus multilocularis | acetyl coenzyme A carboxylase 1 | 0.0478 | 0.0876 | 0.1638 |
Echinococcus granulosus | gamma aminobutyric acid receptor subunit | 0.0397 | 0.0634 | 0.1186 |
Trypanosoma brucei | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.1847 | 0.4926 | 0.921 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.199 | 0.5348 | 1 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0632 | 0.1331 | 0.2489 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.0826 | 0.1904 | 0.356 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.199 | 0.5348 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0429 | 0.0731 | 0.0134 |
Schistosoma mansoni | acetylcholine receptor-related | 0.0397 | 0.0634 | 0.1186 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative | 0.0632 | 0.1331 | 0.2489 |
Mycobacterium tuberculosis | Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) | 0.0654 | 0.1397 | 1 |
Leishmania major | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.199 | 0.5348 | 1 |
Echinococcus granulosus | nAChR subunit | 0.0429 | 0.0731 | 0.1366 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0826 | 0.1904 | 0.356 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.199 | 0.5348 | 1 |
Echinococcus multilocularis | nAChR subunit | 0.0429 | 0.0731 | 0.1366 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0826 | 0.1904 | 0.356 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0826 | 0.1904 | 0.1768 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.199 | 0.5348 | 1 |
Treponema pallidum | glyceraldehyde 3-phosphate dehydrogenase (gap) | 0.199 | 0.5348 | 0.5 |
Loa Loa (eye worm) | carboxyl transferase domain-containing protein | 0.0461 | 0.0826 | 0.0205 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0826 | 0.1904 | 0.1768 |
Onchocerca volvulus | 0.0826 | 0.1904 | 1 | |
Toxoplasma gondii | glyceraldehyde-3-phosphate dehydrogenase GAPDH1 | 0.199 | 0.5348 | 1 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0826 | 0.1904 | 0.356 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1286 | 0.3267 | 0.4531 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | ACC-1 protein | 0.0826 | 0.1904 | 0.1355 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Brugia malayi | glutamate-gated chloride channel alpha3A subunit, putative | 0.0429 | 0.0731 | 0.0134 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Loa Loa (eye worm) | glyceraldehyde 3-phosphate dehydrogenase | 0.1286 | 0.3267 | 0.2811 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0429 | 0.0731 | 0.1366 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0397 | 0.0634 | 0.1186 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.199 | 0.5348 | 1 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.0826 | 0.1904 | 0.1768 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0826 | 0.1904 | 0.356 |
Wolbachia endosymbiont of Brugia malayi | glyceraldehyde-3-phosphate dehydrogenase, GapA | 0.199 | 0.5348 | 1 |
Toxoplasma gondii | acetyl-coA carboxylase ACC2 | 0.0478 | 0.0876 | 0.1638 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0826 | 0.1904 | 0.356 |
Trypanosoma cruzi | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.1847 | 0.4926 | 0.921 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Trypanosoma cruzi | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.1847 | 0.4926 | 0.921 |
Trypanosoma brucei | acetyl-CoA carboxylase | 0.0478 | 0.0876 | 0.1638 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0826 | 0.1904 | 0.1768 |
Leishmania major | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | ACC-1 protein | 0.0826 | 0.1904 | 0.1355 |
Toxoplasma gondii | glyceraldehyde-3-phosphate dehydrogenase GAPDH2 | 0.199 | 0.5348 | 1 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0826 | 0.1904 | 0.356 |
Brugia malayi | glyceraldehyde 3-phosphate dehydrogenase | 0.0632 | 0.1331 | 0.097 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0826 | 0.1904 | 0.356 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | >= 10 % | The ability of the compound to inhibit platelet aggregation was tested; Inhibition >= 10% but < aspirin (34-96%) | ChEMBL. | 3373489 |
Reduction (functional) | = 20 % | Hypolipidemic activity of the compound was expressed as percent decrease in serum cholesterol in Sprague-Dawley rats | ChEMBL. | 3373489 |
Reduction (functional) | = 31 % | Hypolipidemic activity of the compound was expressed as percent decrease in triglycerides in Sprague-Dawley rats | ChEMBL. | 3373489 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.