Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.7367 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 1 | 1 |
Echinococcus granulosus | dna polymerase eta | 0.0019 | 0.7367 | 1 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0017 | 0.6421 | 1 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0019 | 0.7367 | 1 |
Schistosoma mansoni | DNA polymerase eta | 0.0019 | 0.7367 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.7367 | 0.7367 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.7367 | 0.7367 |
Leishmania major | DNA polymerase kappa, putative | 0.0019 | 0.7367 | 0.7367 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.7367 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 1 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.7367 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.6421 | 0.6421 |
Trypanosoma brucei | unspecified product | 0.0013 | 0.379 | 0.5145 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0019 | 0.7367 | 0.7367 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0017 | 0.6421 | 0.6421 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.7367 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.5844 | 0.5844 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.7367 | 1 |
Echinococcus granulosus | dna polymerase kappa | 0.0019 | 0.7367 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.6421 | 0.6421 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.5844 | 0.5844 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0013 | 0.379 | 0.5145 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 1 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.7367 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.7367 | 0.7367 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0013 | 0.379 | 0.5145 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.6421 | 0.6421 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.7367 | 0.7367 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 1 | 1 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0017 | 0.6421 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.7367 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.7367 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 1 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 1 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 1 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 1 | 1 |
Onchocerca volvulus | 0.0023 | 1 | 1 | |
Echinococcus multilocularis | dna polymerase eta | 0.0019 | 0.7367 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.7367 | 1 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0019 | 0.7367 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.7367 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 1 | 1 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0019 | 0.7367 | 1 |
Toxoplasma gondii | propionate-CoA ligase | 0.0007 | 0 | 0.5 |
Leishmania major | DNA polymerase eta, putative | 0.0019 | 0.7367 | 0.7367 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.7367 | 1 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0017 | 0.6421 | 0.6421 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0.7367 | 0.7367 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.7367 | 0.7367 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0017 | 0.6421 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 1 | 1 |
Giardia lamblia | DINP protein human, muc B family | 0.0019 | 0.7367 | 0.5 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0019 | 0.7367 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.7367 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.5844 | 0.5844 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.7367 | 1 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 1 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.5844 | 0.5844 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0013 | 0.379 | 0.5145 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.7367 | 1 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0019 | 0.7367 | 0.7367 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.7367 | 1 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0019 | 0.7367 | 0.7367 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.7367 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.6421 | 0.6421 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0.7367 | 0.7367 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.7367 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 1 | 1 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 1 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.6421 | 0.6421 |
Echinococcus multilocularis | dna polymerase kappa | 0.0019 | 0.7367 | 1 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0019 | 0.7367 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.7367 | 1 |
Trypanosoma brucei | unspecified product | 0.0019 | 0.7367 | 1 |
Trypanosoma brucei | unspecified product | 0.0013 | 0.379 | 0.5145 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0007 | 0 | 0.5 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0019 | 0.7367 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.7367 | 1 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0007 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.