Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.7565 | 1 | 1 |
Trypanosoma cruzi | adenosine monophosphate deaminase, putative | 0.4387 | 0.5741 | 1 |
Trypanosoma cruzi | AMP deaminase, putative | 0.4387 | 0.5741 | 1 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0107 | 0.0007 | 0.0007 |
Trypanosoma brucei | AMP deaminase, putative | 0.4387 | 0.5741 | 0.5 |
Entamoeba histolytica | adenosine deaminase, putative | 0.7565 | 1 | 1 |
Trypanosoma brucei | AMP deaminase, putative | 0.4387 | 0.5741 | 0.5 |
Onchocerca volvulus | Adenosine deaminase homolog | 0.7565 | 1 | 1 |
Leishmania major | AMP deaminase, putative | 0.4387 | 0.5741 | 0.3057 |
Trypanosoma cruzi | AMP deaminase, putative | 0.4387 | 0.5741 | 1 |
Trypanosoma cruzi | adenosine monophosphate deaminase-like protein, putative | 0.4387 | 0.5741 | 1 |
Trypanosoma brucei | AMP deaminase, putative | 0.4387 | 0.5741 | 0.5 |
Leishmania major | adenine aminohydrolase | 0.7565 | 1 | 1 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0107 | 0.0007 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.7565 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.4578 | 0.5997 | 0.5155 |
Mycobacterium ulcerans | adenosine deaminase | 0.7565 | 1 | 0.5 |
Schistosoma mansoni | AMP deaminase | 0.4387 | 0.5741 | 0.5733 |
Echinococcus multilocularis | adenosine deaminase | 0.7565 | 1 | 1 |
Leishmania major | adenosine monophosphate deaminase, putative,AMP deaminase, putative | 0.4387 | 0.5741 | 0.3057 |
Loa Loa (eye worm) | AMP deaminase | 0.4387 | 0.5741 | 0.4845 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0136 | 0.0046 | 0.0046 |
Treponema pallidum | adenosine deaminase | 0.7565 | 1 | 0.5 |
Schistosoma mansoni | adenosine deaminase | 0.7565 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.4578 | 0.5997 | 0.5155 |
Trypanosoma cruzi | AMP deaminase, putative | 0.4387 | 0.5741 | 1 |
Entamoeba histolytica | adenosine deaminase, putative | 0.7565 | 1 | 1 |
Trypanosoma cruzi | AMP deaminase, putative | 0.4387 | 0.5741 | 1 |
Onchocerca volvulus | AMP deaminase 2 homolog | 0.4387 | 0.5741 | 0.3057 |
Trypanosoma cruzi | AMP deaminase, putative | 0.4387 | 0.5741 | 1 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0136 | 0.0046 | 0.0046 |
Loa Loa (eye worm) | hypothetical protein | 0.2987 | 0.3866 | 0.2575 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.7565 | 1 | 1 |
Schistosoma mansoni | adenosine deaminase-related | 0.7565 | 1 | 1 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.7565 | 1 | 0.5 |
Mycobacterium leprae | Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) | 0.7565 | 1 | 0.5 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.7565 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.4578 | 0.5997 | 0.5155 |
Echinococcus multilocularis | AMP deaminase 2 | 0.4387 | 0.5741 | 0.5741 |
Plasmodium vivax | adenosine deaminase, putative | 0.7565 | 1 | 1 |
Echinococcus granulosus | adenosine deaminase | 0.7565 | 1 | 1 |
Plasmodium falciparum | adenosine deaminase | 0.7565 | 1 | 1 |
Leishmania major | AMP deaminase, putative,adenosine monophosphate deaminase-like protein | 0.4387 | 0.5741 | 0.3057 |
Echinococcus granulosus | AMP deaminase 2 | 0.4387 | 0.5741 | 0.5741 |
Leishmania major | AMP deaminase, putative,amp deaminase-like protein | 0.4387 | 0.5741 | 0.3057 |
Loa Loa (eye worm) | hypothetical protein | 0.4578 | 0.5997 | 0.5155 |
Mycobacterium tuberculosis | Probable adenosine deaminase Add (adenosine aminohydrolase) | 0.7565 | 1 | 0.5 |
Trypanosoma brucei | adenosine monophosphate deaminase, putative | 0.4387 | 0.5741 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | = 0 % | In vitro inhibitory activity against H1N9 strain of Influenza neuraminidase (membrane) at 7 mM concentration | ChEMBL. | 9406595 |
Inhibition (binding) | = 0 % | In vitro inhibitory activity against H1N9 strain of Influenza neuraminidase (membrane) at 7 mM concentration | ChEMBL. | 9406595 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.