Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | ssf, putative | 0.0066 | 0.5 | 0.5 |
Giardia lamblia | Peter pan protein | 0.0066 | 0.5 | 0.5 |
Echinococcus multilocularis | peter pan | 0.0066 | 0.5 | 0.5 |
Echinococcus granulosus | peter pan | 0.0066 | 0.5 | 0.5 |
Leishmania major | peter pan protein, putative | 0.0066 | 0.5 | 0.5 |
Schistosoma mansoni | peter pan-related | 0.0066 | 0.5 | 0.5 |
Schistosoma mansoni | peter pan-related | 0.0066 | 0.5 | 0.5 |
Trypanosoma cruzi | peter pan protein, putative | 0.0066 | 0.5 | 0.5 |
Onchocerca volvulus | Peter pan protein homolog | 0.0066 | 0.5 | 0.5 |
Entamoeba histolytica | brix domain containing protein | 0.0066 | 0.5 | 0.5 |
Plasmodium falciparum | BRIX domain, putative | 0.0066 | 0.5 | 0.5 |
Plasmodium vivax | hypothetical protein, conserved | 0.0066 | 0.5 | 0.5 |
Trypanosoma cruzi | peter pan protein, putative | 0.0066 | 0.5 | 0.5 |
Trypanosoma brucei | brix domain containing protein, putative | 0.0066 | 0.5 | 0.5 |
Toxoplasma gondii | brix domain-containing protein | 0.0066 | 0.5 | 0.5 |
Loa Loa (eye worm) | brix domain-containing protein | 0.0066 | 0.5 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | > 100 uM | In vitro minimal inhibitory concentration against Staphylococcus aureus. | ChEMBL. | 14980669 |
MIC (functional) | > 100 uM | Minimal inhibitory concentration against Escherichia coli | ChEMBL. | 14980669 |
MIC (functional) | > 100 uM | Minimal inhibitory concentration against Escherichia coli | ChEMBL. | 14980669 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.