Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | coagulation factor X | Starlite/ChEMBL | References |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 5 uM | In vitro anticoagulant potency measured in human plasma by thrombin generation (TG) assay expressed as 2 x TG | ChEMBL. | 14980670 |
Activity (functional) | = 5 uM | In vitro anticoagulant potency measured in human plasma by thrombin generation (TG) assay expressed as 2 x TG | ChEMBL. | 14980670 |
IC50 (binding) | = 22 nM | Inhibitory concentration against human Coagulation factor X | ChEMBL. | 14980670 |
IC50 (binding) | = 22 nM | Inhibitory concentration against human Coagulation factor X | ChEMBL. | 14980670 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.