Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | tolloid-like 2 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | dipeptidyl-peptidase 9 (S09 family) | 0.0242 | 0.0986 | 0.0986 |
Echinococcus multilocularis | Tolloid protein 1 | 0.0056 | 0.0172 | 0.0164 |
Trypanosoma brucei | oligopeptidase b | 0.0919 | 0.3934 | 0.3271 |
Toxoplasma gondii | acylaminoacyl-peptidase, putative | 0.0242 | 0.0986 | 0.0979 |
Loa Loa (eye worm) | AStacin protease | 0.0035 | 0.0081 | 0.0081 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0242 | 0.0986 | 0.0986 |
Trypanosoma cruzi | serine peptidase, clan SC, family S9A-like protein, putative | 0.0919 | 0.3934 | 0.3271 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0242 | 0.0986 | 0.0986 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0242 | 0.0986 | 0.0986 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0242 | 0.0986 | 0.5 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0242 | 0.0986 | 0.0986 |
Echinococcus multilocularis | prolyl endopeptidase | 0.231 | 1 | 1 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.0242 | 0.0986 | 0.0986 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0242 | 0.0986 | 0.5 |
Trypanosoma cruzi | oligopeptidase b | 0.0919 | 0.3934 | 0.3271 |
Loa Loa (eye worm) | hypothetical protein | 0.0242 | 0.0986 | 0.0986 |
Schistosoma mansoni | subfamily M12A unassigned peptidase (M12 family) | 0.0056 | 0.0172 | 0.0172 |
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.0919 | 0.3934 | 0.5 |
Trypanosoma cruzi | prolyl endopeptidase | 0.231 | 1 | 1 |
Trypanosoma cruzi | oligopeptidase B-like protein, putative | 0.0919 | 0.3934 | 0.3271 |
Leishmania major | prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative | 0.231 | 1 | 1 |
Echinococcus granulosus | prolyl endopeptidase | 0.231 | 1 | 1 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.0242 | 0.0986 | 0.0979 |
Onchocerca volvulus | Prolyl endopeptidase homolog | 0.231 | 1 | 1 |
Toxoplasma gondii | prolyl endopeptidase | 0.231 | 1 | 1 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.231 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.231 | 1 | 1 |
Trypanosoma brucei | serine peptidase, clan SC, family S9A-like protein | 0.0919 | 0.3934 | 0.3271 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.231 | 1 | 1 |
Echinococcus granulosus | acylamino acid releasing enzyme | 0.0242 | 0.0986 | 0.0979 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0242 | 0.0986 | 0.5 |
Toxoplasma gondii | dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein | 0.0242 | 0.0986 | 0.0979 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.0242 | 0.0986 | 0.0986 |
Schistosoma mansoni | acylaminoacyl-peptidase (S09 family) | 0.0242 | 0.0986 | 0.0986 |
Plasmodium falciparum | peptidase, putative | 0.0242 | 0.0986 | 0.5 |
Leishmania major | oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein | 0.0919 | 0.3934 | 0.3271 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0242 | 0.0986 | 0.5 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0242 | 0.0986 | 0.5 |
Mycobacterium tuberculosis | Probable protease II PtrBa [first part] (oligopeptidase B) | 0.2068 | 0.8944 | 1 |
Echinococcus granulosus | Tolloid protein 1 | 0.0056 | 0.0172 | 0.0164 |
Leishmania major | oligopeptidase b | 0.0919 | 0.3934 | 0.3271 |
Trypanosoma brucei | prolyl oligopeptidase, putative | 0.0919 | 0.3934 | 0.3271 |
Loa Loa (eye worm) | multiple epidermal growth factor-like domains 6 | 0.0018 | 0.0008 | 0.0008 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.0242 | 0.0986 | 0.0979 |
Brugia malayi | Fibulin-1 precursor | 0.0018 | 0.0008 | 0.0008 |
Trypanosoma brucei | prolyl endopeptidase | 0.231 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0242 | 0.0986 | 0.5 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0242 | 0.0986 | 0.0986 |
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.0919 | 0.3934 | 0.5 |
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.0242 | 0.0986 | 0.0979 |
Loa Loa (eye worm) | hypothetical protein | 0.0242 | 0.0986 | 0.0986 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0028 | 0.0028 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0242 | 0.0986 | 0.0986 |
Toxoplasma gondii | hypothetical protein | 0.0242 | 0.0986 | 0.0979 |
Loa Loa (eye worm) | bone morphogenetic protein 1b | 0.0056 | 0.0172 | 0.0172 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0242 | 0.0986 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0008 | 0.0008 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0242 | 0.0986 | 0.5 |
Trichomonas vaginalis | Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase | 0.0242 | 0.0986 | 0.5 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0242 | 0.0986 | 0.0986 |
Trypanosoma cruzi | oligopeptidase b | 0.0919 | 0.3934 | 0.3271 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.1038 | 0.4454 | 0.4449 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0242 | 0.0986 | 0.5 |
Plasmodium vivax | hypothetical protein, conserved | 0.0242 | 0.0986 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0162 | 0.0162 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0018 | 0.0008 | 0.0008 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0242 | 0.0986 | 0.5 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.0242 | 0.0986 | 0.0979 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.1038 | 0.4454 | 0.4449 |
Echinococcus multilocularis | acylamino acid releasing enzyme | 0.0242 | 0.0986 | 0.0979 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.