TDR Targets

Basic information

Technical information

TDR Targets ID: 261949
Name: 5-methoxy-1-thiophen-2-ylbenzimidazole
MW: 230.286 | Formula: C12H10N2OS
H donors: 0 H acceptors: 1 LogP: 3.08 Rotable bonds: 2
Rule of 5 violations (Lipinski): 1
SMILES: COc1ccc2c(c1)ncn2c1cccs1
InChi: 1S/C12H10N2OS/c1-15-9-4-5-11-10(7-9)13-8-14(11)12-3-2-6-16-12/h2-8H,1H3
InChiKey: WSBDTCAGQYGFIR-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

5-methoxy-1-(2-thienyl)benzimidazole
5-methoxy-1-thiophen-2-yl-benzimidazole
1-Phenylbenzimidazole deriv. 94

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	fibroblast growth factor receptor 1	Starlite/ChEMBL	References
Mus musculus	platelet derived growth factor receptor, beta polypeptide	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Brugia malayi	Immunoglobulin I-set domain containing protein	Get druggable targets OG5_128769	All targets in OG5_128769
Schistosoma mansoni	tyrosine kinase	Get druggable targets OG5_128769	All targets in OG5_128769
Echinococcus granulosus	basic fibroblast growth factor receptor 1 A	Get druggable targets OG5_128769	All targets in OG5_128769
Echinococcus granulosus	fibroblast growth factor receptor 4	Get druggable targets OG5_128769	All targets in OG5_128769
Echinococcus multilocularis	fibroblast growth factor receptor 4	Get druggable targets OG5_128769	All targets in OG5_128769
Schistosoma japonicum	IPR002048,Calcium-binding EF-hand;IPR001245,Tyrosine protein kinase;IPR000719,Protein kinase;IPR011009,Protein kinase-like,domai	Get druggable targets OG5_128769	All targets in OG5_128769
Echinococcus multilocularis	basic fibroblast growth factor receptor 1 A	Get druggable targets OG5_128769	All targets in OG5_128769
Schistosoma japonicum	Fibroblast growth factor receptor precursor, putative	Get druggable targets OG5_128769	All targets in OG5_128769
Loa Loa (eye worm)	TK protein kinase	Get druggable targets OG5_128769	All targets in OG5_128769

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	acetylcholine receptor subunit beta 1	0.0071	0.1352	0.2643
Mycobacterium tuberculosis	Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB	0.0107	0.2484	0.8342
Loa Loa (eye worm)	hypothetical protein	0.0071	0.1352	0.4413
Mycobacterium leprae	DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE	0.0119	0.286	1
Plasmodium falciparum	thioredoxin reductase	0.0047	0.0591	1
Loa Loa (eye worm)	hypothetical protein	0.0071	0.1352	0.4413
Mycobacterium tuberculosis	Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras	0.0119	0.286	1
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0044	0.0493	0.0964
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0071	0.1352	0.2643
Entamoeba histolytica	hypothetical protein	0.019	0.5116	1
Loa Loa (eye worm)	6-phosphofructokinase	0.011	0.2593	0.8463
Echinococcus multilocularis	nicotinic acetylcholine receptor alpha subunit	0.0071	0.1352	0.2643
Giardia lamblia	Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit	0.003	0.0054	0.5
Echinococcus multilocularis	nAChR subunit	0.0044	0.0493	0.0964
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0044	0.0493	0.0964
Mycobacterium tuberculosis	Probable NADH dehydrogenase Ndh	0.0107	0.2484	0.8342
Echinococcus multilocularis	neuroglian	0.0032	0.0113	0.0221
Entamoeba histolytica	phosphofructokinase, putative	0.011	0.2593	0.5016
Echinococcus granulosus	glycine receptor subunit beta	0.0071	0.1352	0.2643
Schistosoma mansoni	nAChR subunit (ShAR1-beta2-like)	0.0071	0.1352	0.2643
Echinococcus granulosus	nAChR subunit	0.0044	0.0493	0.0964
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.0035	0.0225	0.0734
Schistosoma mansoni	nAChR subunit	0.0071	0.1352	0.2643
Loa Loa (eye worm)	glutathione reductase	0.0047	0.0591	0.1929
Brugia malayi	hypothetical protein	0.019	0.5116	1
Entamoeba histolytica	hypothetical protein	0.019	0.5116	1
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0493	0.1609
Onchocerca volvulus		0.0071	0.1352	1
Entamoeba histolytica	hypothetical protein	0.019	0.5116	1
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0493	0.1609
Echinococcus granulosus	fibroblast growth factor receptor 4	0.0122	0.2951	0.5768
Brugia malayi	excitatory GABA receptor EXP-1A	0.0071	0.1352	0.2643
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0071	0.1352	0.2643
Schistosoma mansoni	transcription factor LCR-F1	0.019	0.5116	1
Schistosoma mansoni	nAChR subunit	0.0071	0.1352	0.2643
Schistosoma mansoni	nephrin	0.0032	0.0113	0.0221
Loa Loa (eye worm)	hypothetical protein	0.0071	0.1352	0.4413
Schistosoma mansoni	nAChR subunit (ShAR1-alpha-like)	0.0071	0.1352	0.2643
Trichomonas vaginalis	phosphofructokinase, putative	0.011	0.2593	1
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.019	0.5116	1
Trypanosoma brucei	ATP-dependent 6-phosphofructokinase, glycosomal	0.011	0.2593	0.2128
Loa Loa (eye worm)	hypothetical protein	0.0071	0.1352	0.4413
Schistosoma mansoni	6-phosphofructokinase	0.011	0.2593	0.5069
Loa Loa (eye worm)	hypothetical protein	0.0071	0.1352	0.4413
Trichomonas vaginalis	phosphofructokinase, putative	0.011	0.2593	1
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.019	0.5116	1
Mycobacterium tuberculosis	Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase)	0.011	0.2593	0.8823
Brugia malayi	Hypothetical glycine receptor like protein T20B12.9 in chromosome III	0.0044	0.0493	0.0964
Loa Loa (eye worm)	hypothetical protein	0.0071	0.1352	0.4413
Loa Loa (eye worm)	hypothetical protein	0.0071	0.1352	0.4413
Loa Loa (eye worm)	phosphofructokinase	0.011	0.2593	0.8463
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0493	0.1609
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0071	0.1352	0.2643
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0493	0.1609
Schistosoma mansoni	6-phosphofructokinase	0.011	0.2593	0.5069
Echinococcus multilocularis	glycine receptor subunit alpha 1	0.0071	0.1352	0.2643
Schistosoma mansoni	nAChR subunit	0.0071	0.1352	0.2643
Echinococcus multilocularis	glycine receptor subunit beta	0.0071	0.1352	0.2643
Schistosoma mansoni	cell adhesion molecule	0.0033	0.0144	0.0282
Loa Loa (eye worm)	hypothetical protein	0.0071	0.1352	0.4413
Leishmania major	ATP-dependent phosphofructokinase	0.011	0.2593	0.2128
Echinococcus granulosus	nicotinic acetylcholine receptor alpha subunit	0.0071	0.1352	0.2643
Loa Loa (eye worm)	hypothetical protein	0.0071	0.1352	0.4413
Loa Loa (eye worm)	acetylcholine receptor alpha subunit	0.0071	0.1352	0.4413
Brugia malayi	glutamate-gated chloride channel alpha3A subunit, putative	0.0044	0.0493	0.0964
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0071	0.1352	0.2643
Treponema pallidum	diphosphate--fructose-6-phosphate 1-phosphotransferase	0.011	0.2593	1
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0071	0.1352	0.2643
Brugia malayi	acetylcholine receptor alpha subunit precursor, putative	0.0071	0.1352	0.2643
Loa Loa (eye worm)	thioredoxin reductase	0.0047	0.0591	0.1929
Echinococcus multilocularis	acetylcholine receptor subunit beta 1	0.0071	0.1352	0.2643
Echinococcus multilocularis	roundabout 2	0.0036	0.0258	0.0504
Brugia malayi	Cation transporter family protein	0.0071	0.1352	0.2643
Echinococcus granulosus	nicotinic acetylcholine receptor subunit alpha 8	0.0071	0.1352	0.2643
Entamoeba histolytica	hypothetical protein	0.019	0.5116	1
Onchocerca volvulus		0.0071	0.1352	1
Loa Loa (eye worm)	hypothetical protein	0.0071	0.1352	0.4413
Onchocerca volvulus		0.0071	0.1352	1
Schistosoma mansoni	nAChR subunit	0.0071	0.1352	0.2643
Echinococcus multilocularis	nicotinic acetylcholine receptor beta 1 subunit	0.0071	0.1352	0.2643
Mycobacterium tuberculosis	Probable dehydrogenase	0.0107	0.2484	0.8342
Loa Loa (eye worm)	ACC-1 protein	0.0071	0.1352	0.4413
Mycobacterium leprae	PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE)	0.011	0.2593	0.2897
Mycobacterium tuberculosis	Probable oxidoreductase	0.0119	0.286	1
Plasmodium vivax	glutathione reductase, putative	0.0047	0.0591	1
Mycobacterium tuberculosis	Probable reductase	0.0107	0.2484	0.8342
Loa Loa (eye worm)	GABA receptor subunit	0.0044	0.0493	0.1609
Onchocerca volvulus		0.0071	0.1352	1
Loa Loa (eye worm)	LGC-31 protein	0.0071	0.1352	0.4413
Brugia malayi	6-phosphofructokinase	0.011	0.2593	0.5069
Echinococcus multilocularis	6 phosphofructokinase	0.011	0.2593	0.5069
Brugia malayi	Hypothetical glycine receptor like protein T20B12.9 in chromosome III	0.0071	0.1352	0.2643
Mycobacterium tuberculosis	NAD(P)H quinone reductase LpdA	0.0119	0.286	1
Trypanosoma cruzi	ATP-dependent 6-phosphofructokinase, glycosomal	0.011	0.2593	1
Echinococcus multilocularis	nicotinic acetylcholine receptor subunit alpha 8	0.0071	0.1352	0.2643
Trypanosoma brucei	pteridine reductase 1	0.0345	1	1
Echinococcus granulosus	thioredoxin glutathione reductase	0.0047	0.0591	0.1156
Echinococcus granulosus	Cys loop ligand gated ion channel subunit	0.0071	0.1352	0.2643
Chlamydia trachomatis	fructose-6-phosphate phosphotransferase	0.003	0.0054	0.5
Loa Loa (eye worm)	nicotinic acetylcholine receptor alpha subunit	0.0071	0.1352	0.4413
Brugia malayi	phosphofructokinase	0.011	0.2593	0.5069
Schistosoma mansoni	nAChR subunit (ShAR1-beta-like)	0.0071	0.1352	0.2643
Loa Loa (eye worm)	hypothetical protein	0.0071	0.1352	0.4413
Plasmodium vivax	thioredoxin reductase, putative	0.0047	0.0591	1
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0493	0.1609
Echinococcus multilocularis	glycine receptor subunit beta	0.0071	0.1352	0.2643
Echinococcus granulosus	nAChR subunit	0.0071	0.1352	0.2643
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0258	0.0841
Onchocerca volvulus		0.0071	0.1352	1
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0071	0.1352	0.2643
Echinococcus granulosus	basic fibroblast growth factor receptor 1 A	0.0122	0.2951	0.5768
Schistosoma mansoni	hypothetical protein	0.019	0.5116	1
Brugia malayi	Cation transporter family protein	0.0071	0.1352	0.2643
Mycobacterium tuberculosis	Putative ferredoxin reductase	0.0107	0.2484	0.8342
Loa Loa (eye worm)	excitatory GABA receptor EXP-1A	0.0071	0.1352	0.4413
Loa Loa (eye worm)	ACC-1 protein	0.0071	0.1352	0.4413
Echinococcus multilocularis	glycine receptor subunit alpha 1	0.0071	0.1352	0.2643
Trichomonas vaginalis	phosphofructokinase, putative	0.011	0.2593	1
Toxoplasma gondii	thioredoxin reductase	0.0047	0.0591	1
Schistosoma mansoni	nAChR subunit	0.0071	0.1352	0.2643
Echinococcus granulosus	glycine receptor subunit alpha 1	0.0071	0.1352	0.2643
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0493	0.1609
Loa Loa (eye worm)	hypothetical protein	0.0071	0.1352	0.4413
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0071	0.1352	0.2643
Onchocerca volvulus	Putative nachr subunit	0.0071	0.1352	1
Schistosoma mansoni	nAChR subunit	0.0071	0.1352	0.2643
Chlamydia trachomatis	fructose-6-phosphate phosphotransferase	0.003	0.0054	0.5
Entamoeba histolytica	phosphofructokinase, putative	0.011	0.2593	0.5016
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0493	0.1609
Echinococcus granulosus	glycine receptor subunit beta	0.0071	0.1352	0.2643
Echinococcus multilocularis	basic fibroblast growth factor receptor 1 A	0.0122	0.2951	0.5768
Mycobacterium tuberculosis	Probable membrane NADH dehydrogenase NdhA	0.0107	0.2484	0.8342
Brugia malayi	nicotinic acetylcholine receptor alpha subunit, putative	0.0071	0.1352	0.2643
Entamoeba histolytica	hypothetical protein	0.0044	0.0493	0.0868
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0044	0.0493	0.0964
Trichomonas vaginalis	phosphofructokinase, putative	0.011	0.2593	1
Loa Loa (eye worm)	hypothetical protein	0.0071	0.1352	0.4413
Brugia malayi	gamma-aminobutyric-acid receptor beta subunit precursor	0.0071	0.1352	0.2643
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0144	0.0472
Brugia malayi	Cation transporter family protein	0.0071	0.1352	0.2643
Loa Loa (eye worm)	hypothetical protein	0.0071	0.1352	0.4413
Loa Loa (eye worm)	hypothetical protein	0.0071	0.1352	0.4413
Echinococcus granulosus	glycine receptor subunit alpha 1	0.0071	0.1352	0.2643
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0071	0.1352	0.2643
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0258	0.0841
Echinococcus granulosus	neuronal acetylcholine receptor subunit alpha 4	0.0071	0.1352	0.2643
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0071	0.1352	0.2643
Echinococcus granulosus	neuroglian	0.0032	0.0113	0.0221
Brugia malayi	Thioredoxin reductase	0.0047	0.0591	0.1156
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0035	0.0225	0.044
Echinococcus granulosus	roundabout 2	0.0036	0.0258	0.0504
Loa Loa (eye worm)	nicotinic acetylcholine receptor non-alpha subunit	0.0071	0.1352	0.4413
Echinococcus multilocularis	nicotinic acetylcholine receptor a11 subunit	0.0071	0.1352	0.2643
Mycobacterium ulcerans	6-phosphofructokinase	0.011	0.2593	0.5
Onchocerca volvulus		0.0071	0.1352	1
Echinococcus multilocularis	fibroblast growth factor receptor 4	0.0122	0.2951	0.5768
Echinococcus granulosus	glycine receptor subunit alpha 1	0.0071	0.1352	0.2643
Echinococcus multilocularis	Cys loop ligand gated ion channel subunit	0.0071	0.1352	0.2643
Loa Loa (eye worm)	6-phosphofructokinase	0.011	0.2593	0.8463
Brugia malayi	acetylcholine receptor, alpha-type subunit unc-38 precursor	0.0071	0.1352	0.2643
Loa Loa (eye worm)	hypothetical protein	0.0071	0.1352	0.4413
Echinococcus multilocularis	neuronal acetylcholine receptor subunit alpha 4	0.0071	0.1352	0.2643
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0493	0.1609
Loa Loa (eye worm)	hypothetical protein	0.0071	0.1352	0.4413
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0125	0.3064	0.5989
Loa Loa (eye worm)	hypothetical protein	0.0071	0.1352	0.4413
Brugia malayi	nicotinic acetylcholine receptor beta-1 chain precursor	0.0071	0.1352	0.2643
Loa Loa (eye worm)	hypothetical protein	0.0071	0.1352	0.4413
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0493	0.1609
Echinococcus multilocularis	nAChR subunit	0.0071	0.1352	0.2643
Brugia malayi	6-phosphofructokinase	0.011	0.2593	0.5069
Echinococcus granulosus	twitchin	0.0032	0.0113	0.0221
Schistosoma mansoni	neurotransmitter gated ion channel	0.0044	0.0493	0.0964
Schistosoma mansoni	tyrosine kinase	0.0122	0.2951	0.5768
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0071	0.1352	0.2643
Brugia malayi	acetylcholine receptor protein, alpha-like chain, putative	0.0071	0.1352	0.2643
Loa Loa (eye worm)	TK protein kinase	0.0125	0.3064	1
Echinococcus granulosus	nicotinic acetylcholine receptor beta 1 subunit	0.0071	0.1352	0.2643
Brugia malayi	glutathione reductase	0.0047	0.0591	0.1156
Schistosoma mansoni	nAChR subunit	0.0071	0.1352	0.2643
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0071	0.1352	0.2643
Echinococcus granulosus	neurotracting:lsamp:neurotrimin:obcam	0.0033	0.0144	0.0282
Loa Loa (eye worm)	glutamate-gated chloride channel alpha3A subunit	0.0071	0.1352	0.4413
Loa Loa (eye worm)	ligand-Gated ion Channel family member	0.0071	0.1352	0.4413
Schistosoma mansoni	nicotinic acetylcholine receptor alpha	0.0044	0.0493	0.0964
Echinococcus multilocularis	thioredoxin glutathione reductase	0.0047	0.0591	0.1156
Echinococcus multilocularis	glycine receptor subunit alpha 1	0.0071	0.1352	0.2643
Entamoeba histolytica	phosphofructokinase, putative	0.011	0.2593	0.5016
Plasmodium falciparum	glutathione reductase	0.0047	0.0591	1
Echinococcus granulosus	nicotinic acetylcholine receptor subunit type	0.0071	0.1352	0.2643
Echinococcus granulosus	6 phosphofructokinase	0.011	0.2593	0.5069
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0071	0.1352	0.2643
Echinococcus granulosus	nicotinic acetylcholine receptor a11 subunit	0.0071	0.1352	0.2643

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	= 2.5 uM	Inhibition of phosphorylation of a random glutamate/tyrosine copolymer in lysates of transfected Sf9 insect cells overexpressing mouse platelet-derived growth factor receptor beta	ChEMBL.	9876115
IC50 (binding)	= 2.5 uM	Inhibition of phosphorylation of a random glutamate/tyrosine copolymer in lysates of transfected Sf9 insect cells overexpressing mouse platelet-derived growth factor receptor beta	ChEMBL.	9876115
IC50 (binding)	= 5.3 uM	Inhibition of phosphorylation of a random glutamate/tyrosine copolymer in lysates of transfected Sf9 insect cells overexpressing human fibroblast growth factor receptor 1	ChEMBL.	9876115
IC50 (binding)	= 5.3 uM	Inhibition of phosphorylation of a random glutamate/tyrosine copolymer in lysates of transfected Sf9 insect cells overexpressing human fibroblast growth factor receptor 1	ChEMBL.	9876115

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL153084
PubChem: 5328492

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 261949