Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.1157 | 1 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0019 | 0.0086 | 0.0686 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0012 | 0.0043 | 0.0062 |
Echinococcus multilocularis | heat shock protein 90 | 0.0013 | 0.0049 | 0.007 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0007 | 0.0011 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0021 | 0.0094 | 0.0134 |
Echinococcus multilocularis | kinesin family 1 | 0.0195 | 0.1179 | 0.1688 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0012 | 0.0043 | 0.005 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0012 | 0.0043 | 0.0312 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0012 | 0.0043 | 0.0062 |
Brugia malayi | neuropeptide F receptor | 0.0012 | 0.0043 | 0.005 |
Plasmodium vivax | kinesin-5 | 0.0025 | 0.0123 | 0.0279 |
Brugia malayi | follicle stimulating hormone receptor | 0.0012 | 0.0043 | 0.005 |
Echinococcus multilocularis | fmrfamide receptor | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0075 | 0.0433 | 0.0619 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0012 | 0.0043 | 0.0062 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0012 | 0.0043 | 0.0062 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0012 | 0.0043 | 0.0062 |
Trichomonas vaginalis | heat shock protein, putative | 0.0011 | 0.0032 | 0.032 |
Echinococcus granulosus | orexin receptor type 2 | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0094 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0012 | 0.0043 | 0.0062 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0012 | 0.0043 | 0.0062 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0012 | 0.0043 | 0.0062 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0019 | 0.0086 | 0.0124 |
Echinococcus multilocularis | expressed protein | 0.0006 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0012 | 0.0043 | 0.0312 |
Echinococcus multilocularis | GPCR, family 2 | 0.001 | 0.0025 | 0.0035 |
Echinococcus multilocularis | neuropeptide receptor | 0.0012 | 0.0043 | 0.0062 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0075 | 0.0433 | 0.0619 |
Schistosoma mansoni | amine GPCR | 0.0012 | 0.0043 | 0.0062 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0012 | 0.0043 | 0.0312 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.001 | 0.0025 | 0.0025 |
Echinococcus granulosus | heat shock protein 90 | 0.0013 | 0.0049 | 0.007 |
Schistosoma mansoni | hypothetical protein | 0.001 | 0.0025 | 0.0035 |
Echinococcus granulosus | neuropeptide s receptor | 0.0012 | 0.0043 | 0.0062 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0043 | 0.005 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0021 | 0.0094 | 0.0134 |
Schistosoma mansoni | cpg binding protein | 0.0019 | 0.0086 | 0.0123 |
Schistosoma mansoni | amine GPCR | 0.0012 | 0.0043 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0012 | 0.0043 | 0.0312 |
Schistosoma mansoni | P2X receptor subunit | 0.1126 | 0.6989 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0043 | 0.0062 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0043 | 0.005 |
Onchocerca volvulus | 0.0021 | 0.0094 | 0.0051 | |
Schistosoma mansoni | cpg binding protein | 0.002 | 0.0093 | 0.0133 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | heat shock protein | 0.0013 | 0.0049 | 0.007 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0032 | 0.0166 | 0.0557 |
Leishmania major | heat shock protein 83-1 | 0.0013 | 0.0049 | 0.0064 |
Schistosoma mansoni | neuropeptide receptor | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0012 | 0.0043 | 0.0062 |
Leishmania major | heat shock protein 83-1 | 0.0013 | 0.0049 | 0.0064 |
Trichomonas vaginalis | heat shock protein, putative | 0.0013 | 0.0049 | 0.0496 |
Echinococcus multilocularis | allatostatin A receptor | 0.0012 | 0.0043 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0012 | 0.0043 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Brugia malayi | Kinesin motor domain containing protein | 0.0025 | 0.0123 | 0.016 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.1126 | 0.6989 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.0012 | 0.0043 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0012 | 0.0043 | 0.0312 |
Echinococcus granulosus | GPCR family 2 | 0.001 | 0.0025 | 0.0035 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0021 | 0.0094 | 0.012 |
Echinococcus multilocularis | neuropeptide receptor | 0.0012 | 0.0043 | 0.0062 |
Trypanosoma cruzi | telomerase reverse transcriptase, putative | 0.044 | 0.2706 | 1 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.0011 | 0.0032 | 0.0046 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0012 | 0.0043 | 0.0062 |
Echinococcus multilocularis | endoplasmin | 0.0011 | 0.0032 | 0.0046 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0012 | 0.0043 | 0.0062 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0021 | 0.0094 | 0.0134 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0012 | 0.0043 | 0.005 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0012 | 0.0043 | 0.0062 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0012 | 0.0043 | 0.0062 |
Brugia malayi | GnHR receptor homolog | 0.0012 | 0.0043 | 0.005 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0021 | 0.0094 | 0.0134 |
Trichomonas vaginalis | endoplasmin, putative | 0.0008 | 0.0017 | 0.0161 |
Treponema pallidum | heat shock protein 90 | 0.0011 | 0.0032 | 1 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | neuropeptide receptor | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | hypothetical protein | 0.001 | 0.0025 | 0.0035 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | amine GPCR | 0.0012 | 0.0043 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0153 | 0.1268 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0012 | 0.0043 | 0.0062 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0014 | 0.0056 | 0.0079 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0012 | 0.0043 | 0.005 |
Echinococcus multilocularis | sex peptide receptor | 0.0012 | 0.0043 | 0.0062 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0012 | 0.0043 | 0.0062 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.1126 | 0.6989 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0012 | 0.0043 | 0.0062 |
Echinococcus multilocularis | muscleblind protein | 0.0191 | 0.1157 | 0.1656 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0012 | 0.0043 | 0.0062 |
Leishmania major | heat shock protein 83-1 | 0.0013 | 0.0049 | 0.0064 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0012 | 0.0043 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0012 | 0.0043 | 0.0312 |
Leishmania major | heat shock protein 83-1 | 0.0013 | 0.0049 | 0.0064 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0012 | 0.0043 | 0.0312 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0032 | 0.0166 | 0.0442 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0014 | 0.0056 | 0.0079 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0012 | 0.0043 | 0.0062 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.1126 | 0.6989 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.0011 | 0.0032 | 0.032 |
Toxoplasma gondii | RNA-directed DNA polymerase | 0.044 | 0.2706 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0037 | 0.0199 | 0.0565 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0012 | 0.0043 | 0.0062 |
Onchocerca volvulus | 0.0019 | 0.0086 | 0.0043 | |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0012 | 0.0043 | 0.005 |
Trichomonas vaginalis | heat shock protein, putative | 0.0008 | 0.0017 | 0.0161 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0012 | 0.0043 | 0.0062 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0013 | 0.0049 | 0.0127 |
Echinococcus multilocularis | somatostatin receptor | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | biogenic amine receptor | 0.0012 | 0.0043 | 0.0062 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0012 | 0.0043 | 0.0062 |
Brugia malayi | G-protein coupled receptor | 0.0012 | 0.0043 | 0.005 |
Echinococcus granulosus | serotonin receptor | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | histamine h1 receptor | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0012 | 0.0043 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Echinococcus granulosus | muscleblind protein | 0.0191 | 0.1157 | 0.1656 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0021 | 0.0094 | 0.0134 |
Brugia malayi | Dopamine receptor protein 1 | 0.0012 | 0.0043 | 0.005 |
Brugia malayi | G-protein coupled receptor | 0.0012 | 0.0043 | 0.005 |
Plasmodium falciparum | heat shock protein 90 | 0.0013 | 0.0049 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0032 | 0.0166 | 0.0564 |
Echinococcus granulosus | cpg binding protein | 0.002 | 0.0093 | 0.0133 |
Schistosoma mansoni | ferritin light chain | 0.0006 | 0.0001 | 0.0001 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0012 | 0.0043 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0075 | 0.0433 | 0.0619 |
Brugia malayi | heat shock protein 90 | 0.0013 | 0.0049 | 0.0058 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0012 | 0.0043 | 0.0062 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0012 | 0.0043 | 0.0062 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0043 | 0.005 |
Schistosoma mansoni | hypothetical protein | 0.0102 | 0.0604 | 0.0864 |
Echinococcus granulosus | somatostatin receptor | 0.0012 | 0.0043 | 0.0062 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0141 | 0.0844 | 0.728 |
Leishmania major | telomerase reverse transcriptase, putative | 0.044 | 0.2706 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0013 | 0.0049 | 0.0064 |
Brugia malayi | G protein-coupled receptor | 0.0012 | 0.0043 | 0.005 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0012 | 0.0043 | 0.0062 |
Echinococcus multilocularis | cpg binding protein | 0.002 | 0.0093 | 0.0133 |
Toxoplasma gondii | kinesin motor domain-containing protein | 0.0025 | 0.0123 | 0.0279 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0012 | 0.0043 | 0.0062 |
Leishmania major | heat shock protein 83-1 | 0.0013 | 0.0049 | 0.0064 |
Schistosoma mansoni | kinesin eg-5 | 0.0025 | 0.0123 | 0.0176 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0012 | 0.0043 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | biogenic amine receptor | 0.0012 | 0.0043 | 0.0062 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0012 | 0.0043 | 0.0062 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0012 | 0.0043 | 0.0062 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0012 | 0.0043 | 0.0062 |
Echinococcus multilocularis | g protein coupled receptor | 0.0012 | 0.0043 | 0.0062 |
Trypanosoma brucei | telomerase reverse transcriptase | 0.044 | 0.2706 | 1 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | myosin xvIII | 0.0012 | 0.0043 | 0.0062 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0043 | 0.005 |
Brugia malayi | neuropeptide F receptor | 0.0012 | 0.0043 | 0.005 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0012 | 0.0043 | 0.0062 |
Trypanosoma cruzi | telomerase reverse transcriptase, putative | 0.044 | 0.2706 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0013 | 0.0049 | 0.0064 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0012 | 0.0043 | 0.0062 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0043 | 0.005 |
Echinococcus granulosus | expressed protein | 0.0006 | 0.0001 | 0.0001 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0012 | 0.0043 | 0.0062 |
Echinococcus granulosus | allatostatin A receptor | 0.0012 | 0.0043 | 0.0062 |
Echinococcus granulosus | heat shock protein 90 | 0.0011 | 0.0032 | 0.0046 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0042 | 0.0226 | 0.0324 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.001 | 0.0025 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0094 | 0.0751 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0094 | 0.0751 |
Leishmania major | heat shock protein 83-1 | 0.0013 | 0.0049 | 0.0064 |
Echinococcus granulosus | g protein coupled receptor | 0.0012 | 0.0043 | 0.0062 |
Echinococcus granulosus | endoplasmin | 0.0011 | 0.0032 | 0.0046 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0012 | 0.0043 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | adenoreceptor | 0.0012 | 0.0043 | 0.0062 |
Brugia malayi | Pre-SET motif family protein | 0.0141 | 0.0844 | 0.1155 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0012 | 0.0043 | 0.0312 |
Echinococcus granulosus | ferritin | 0.0006 | 0.0001 | 0.0001 |
Brugia malayi | Telomerase reverse transcriptase | 0.117 | 0.7259 | 1 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.0011 | 0.0032 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Echinococcus granulosus | geminin | 0.0102 | 0.0604 | 0.0864 |
Brugia malayi | Dopamine receptor protein 2 | 0.0012 | 0.0043 | 0.005 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0007 | 0.0011 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0011 | 0.0032 | 0.0064 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0032 | 0.0166 | 0.0442 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0012 | 0.0043 | 0.0312 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Brugia malayi | Serotonin receptor | 0.0012 | 0.0043 | 0.005 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Schistosoma mansoni | amine GPCR | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | hypothetical protein | 0.001 | 0.0025 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0025 | 0.0151 |
Leishmania major | heat shock protein 83-1 | 0.0013 | 0.0049 | 0.0064 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0021 | 0.0094 | 0.0134 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0012 | 0.0043 | 0.0062 |
Echinococcus granulosus | fmrfamide receptor | 0.0012 | 0.0043 | 0.0062 |
Loa Loa (eye worm) | kinesin-like protein KLP2 | 0.0025 | 0.0123 | 0.1006 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0012 | 0.0043 | 0.0062 |
Brugia malayi | hypothetical protein | 0.0032 | 0.0166 | 0.022 |
Leishmania major | heat shock protein 83-1 | 0.0013 | 0.0049 | 0.0064 |
Brugia malayi | sulfakinin receptor protein | 0.0012 | 0.0043 | 0.005 |
Schistosoma mansoni | ferritin | 0.0006 | 0.0001 | 0.0001 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.001 | 0.0025 | 0.0035 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0012 | 0.0043 | 0.0312 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0012 | 0.0043 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0012 | 0.0043 | 0.0062 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0012 | 0.0043 | 0.0062 |
Leishmania major | heat shock protein 83-1 | 0.0013 | 0.0049 | 0.0064 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0012 | 0.0043 | 0.0062 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0043 | 0.005 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0191 | 0.1157 | 0.1656 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0012 | 0.0043 | 0.0062 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0012 | 0.0043 | 0.0062 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0012 | 0.0043 | 0.0062 |
Brugia malayi | AKH receptor | 0.0012 | 0.0043 | 0.005 |
Brugia malayi | Melatonin receptor type 1A | 0.0012 | 0.0043 | 0.005 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0012 | 0.0043 | 0.0062 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0012 | 0.0043 | 0.005 |
Echinococcus multilocularis | g protein coupled receptor | 0.0012 | 0.0043 | 0.0062 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0012 | 0.0043 | 0.0062 |
Echinococcus granulosus | g-protein coupled receptor | 0.0012 | 0.0043 | 0.0062 |
Brugia malayi | RE15519p | 0.0012 | 0.0043 | 0.005 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.003 | 0.0153 | 0.0202 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.001 | 0.0025 | 0.0151 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.003 | 0.0153 | 0.0202 |
Echinococcus multilocularis | fmrfamide receptor | 0.0012 | 0.0043 | 0.0062 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0043 | 0.005 |
Trichomonas vaginalis | heat shock protein, putative | 0.0011 | 0.0032 | 0.032 |
Schistosoma mansoni | opsin-like receptor | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | hypothetical protein | 0.0102 | 0.0604 | 0.0864 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0012 | 0.0043 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0166 | 0.1383 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Echinococcus granulosus | sex peptide receptor | 0.0012 | 0.0043 | 0.0062 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0032 | 0.0166 | 0.0557 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0013 | 0.0049 | 0.0127 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0012 | 0.0043 | 0.005 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0043 | 0.005 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0012 | 0.0043 | 0.0062 |
Mycobacterium ulcerans | heat shock protein 90 | 0.0011 | 0.0032 | 1 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0013 | 0.0049 | 0.0361 |
Giardia lamblia | Telomerase catalytic subunit | 0.044 | 0.2706 | 1 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0012 | 0.0043 | 0.0062 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0075 | 0.0433 | 0.0619 |
Leishmania major | heat shock protein 83-1 | 0.0013 | 0.0049 | 0.0064 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0075 | 0.0433 | 0.37 |
Schistosoma mansoni | hypothetical protein | 0.001 | 0.0025 | 0.0035 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0011 | 0.0032 | 0.0064 |
Schistosoma mansoni | ferritin light chain | 0.0006 | 0.0001 | 0.0001 |
Echinococcus multilocularis | serotonin receptor | 0.0012 | 0.0043 | 0.0062 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.001 | 0.0025 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.1126 | 0.6989 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.0012 | 0.0043 | 0.0062 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0012 | 0.0043 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0012 | 0.0043 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Leishmania major | heat shock protein 83-1 | 0.0013 | 0.0049 | 0.0064 |
Echinococcus multilocularis | heat shock protein 90 | 0.0011 | 0.0032 | 0.0046 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.003 | 0.0153 | 0.1268 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Schistosoma mansoni | amine GPCR | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | P2X receptor subunit | 0.0622 | 0.3842 | 0.5498 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0012 | 0.0043 | 0.005 |
Trichomonas vaginalis | set domain proteins, putative | 0.016 | 0.0965 | 1 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0012 | 0.0043 | 0.005 |
Schistosoma mansoni | P2X receptor subunit | 0.1126 | 0.6989 | 1 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0043 | 0.005 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0012 | 0.0043 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Leishmania major | heat shock protein 83-1 | 0.0013 | 0.0049 | 0.0064 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0012 | 0.0043 | 0.0062 |
Echinococcus multilocularis | ferritin | 0.0006 | 0.0001 | 0.0001 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | apoferritin-2 | 0.0006 | 0.0001 | 0.0001 |
Schistosoma mansoni | P2X receptor subunit | 0.0622 | 0.3842 | 0.5498 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0075 | 0.0433 | 0.0619 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0012 | 0.0043 | 0.0062 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.001 | 0.0025 | 0.0035 |
Echinococcus multilocularis | g protein coupled receptor | 0.0012 | 0.0043 | 0.0062 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0012 | 0.0043 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Echinococcus multilocularis | geminin | 0.0102 | 0.0604 | 0.0864 |
Entamoeba histolytica | kinesin, putative | 0.0025 | 0.0123 | 1 |
Schistosoma mansoni | endoplasmin | 0.0013 | 0.0049 | 0.007 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0012 | 0.0043 | 0.0062 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0032 | 0.0166 | 0.0564 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0013 | 0.0049 | 0.0127 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0012 | 0.0043 | 0.0062 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0012 | 0.0043 | 0.0062 |
Brugia malayi | larval opioid receptor | 0.0012 | 0.0043 | 0.005 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0075 | 0.0433 | 0.0619 |
Loa Loa (eye worm) | endoplasmin | 0.0013 | 0.0049 | 0.0361 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.1126 | 0.6989 | 1 |
Giardia lamblia | Kinesin-5 | 0.0025 | 0.0123 | 0.0341 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | opsin-like receptor | 0.0012 | 0.0043 | 0.0062 |
Leishmania major | hypothetical protein, conserved | 0.0032 | 0.0166 | 0.0503 |
Plasmodium vivax | SET domain protein, putative | 0.0021 | 0.0094 | 0.0169 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0012 | 0.0043 | 0.0312 |
Leishmania major | heat shock protein 83-1 | 0.0013 | 0.0049 | 0.0064 |
Schistosoma mansoni | ferritin | 0.0006 | 0.0001 | 0.0001 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0013 | 0.0049 | 0.0127 |
Brugia malayi | CXXC zinc finger family protein | 0.0019 | 0.0086 | 0.0109 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0043 | 0.005 |
Brugia malayi | Pre-SET motif family protein | 0.0021 | 0.0094 | 0.012 |
Schistosoma mansoni | hypothetical protein | 0.0014 | 0.0056 | 0.0079 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.1126 | 0.6989 | 1 |
Schistosoma mansoni | endoplasmin | 0.0013 | 0.0049 | 0.007 |
Echinococcus granulosus | neuropeptide receptor | 0.0012 | 0.0043 | 0.0062 |
Echinococcus multilocularis | heat shock protein | 0.0013 | 0.0049 | 0.007 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0013 | 0.0049 | 0.0064 |
Plasmodium vivax | telomerase reverse transcriptase, putative | 0.044 | 0.2706 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.001 | 0.0025 | 0.0025 |
Echinococcus granulosus | neuropeptide receptor | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0012 | 0.0043 | 0.0062 |
Brugia malayi | Dopamine receptor | 0.0012 | 0.0043 | 0.005 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0012 | 0.0043 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0032 | 0.0166 | 0.0442 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0012 | 0.0043 | 0.0062 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0012 | 0.0043 | 0.0062 |
Brugia malayi | hypothetical protein | 0.0021 | 0.0095 | 0.0122 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | heat shock protein | 0.0013 | 0.0049 | 0.007 |
Brugia malayi | putative neuropeptide receptor | 0.0012 | 0.0043 | 0.005 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0013 | 0.0049 | 0.0127 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.1157 | 1 |
Plasmodium falciparum | telomerase reverse transcriptase | 0.044 | 0.2706 | 1 |
Schistosoma mansoni | ferritin | 0.0006 | 0.0001 | 0.0001 |
Onchocerca volvulus | 0.016 | 0.0965 | 0.0926 | |
Plasmodium falciparum | kinesin-5 | 0.0025 | 0.0123 | 0.0396 |
Brugia malayi | Muscleblind-like protein | 0.0191 | 0.1157 | 0.1586 |
Echinococcus multilocularis | serotonin receptor | 0.0012 | 0.0043 | 0.0062 |
Mycobacterium leprae | PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) | 0.0011 | 0.0032 | 1 |
Echinococcus granulosus | hypothetical protein | 0.0012 | 0.0043 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Brugia malayi | Serotonin receptor | 0.0012 | 0.0043 | 0.005 |
Schistosoma mansoni | hypothetical protein | 0.0169 | 0.1022 | 0.1462 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0012 | 0.0043 | 0.0062 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0012 | 0.0043 | 0.0062 |
Echinococcus granulosus | heat shock protein | 0.0013 | 0.0049 | 0.007 |
Schistosoma mansoni | ferritin | 0.0006 | 0.0001 | 0.0001 |
Echinococcus granulosus | kinesin family 1 | 0.0195 | 0.1179 | 0.1688 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0012 | 0.0043 | 0.0062 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0012 | 0.0043 | 0.0062 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0012 | 0.0043 | 0.0062 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0012 | 0.0043 | 0.0062 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0021 | 0.0094 | 0.0169 |
Echinococcus granulosus | g protein coupled receptor | 0.0012 | 0.0043 | 0.0062 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0012 | 0.0043 | 0.0062 |
Leishmania major | heat shock protein 83-1 | 0.0013 | 0.0049 | 0.0064 |
Brugia malayi | ORL1-like opioid receptor | 0.0012 | 0.0043 | 0.005 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0012 | 0.0043 | 0.0062 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0012 | 0.0043 | 0.0062 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0043 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Leishmania major | heat shock protein 83-1 | 0.0013 | 0.0049 | 0.0064 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | neuropeptide receptor | 0.0012 | 0.0043 | 0.0062 |
Mycobacterium tuberculosis | Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) | 0.0011 | 0.0032 | 1 |
Schistosoma mansoni | cpg binding protein | 0.002 | 0.0093 | 0.0133 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0021 | 0.0094 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0043 | 0.0312 |
Schistosoma mansoni | biogenic amine receptor | 0.0012 | 0.0043 | 0.0062 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0075 | 0.0433 | 0.0619 |
Brugia malayi | Endoplasmin precursor | 0.0013 | 0.0049 | 0.0058 |
Schistosoma mansoni | apoferritin-2 | 0.0006 | 0.0001 | 0.0001 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0075 | 0.0433 | 0.0587 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
EC50 (functional) | = 51 nM | Concentration required to reverse inhibition of T-cell proliferation, by measuring [3H]-thymidine uptake up to a concentration of 10 uM (Antagonistic activity, immunosuppression) | ChEMBL. | No reference |
IC50 (functional) | > 10000 nM | Agonistic activity in a murine splenic T-cell proliferation assay was calculated by measurement of [3H]-thymidine uptake relative to control | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.