Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | coagulation factor X | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0182 | 0.1343 | 0.1343 |
Schistosoma mansoni | acetylcholinesterase | 0.0182 | 0.1343 | 0.1343 |
Echinococcus granulosus | acetylcholinesterase | 0.1076 | 1 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0182 | 0.1343 | 0.5 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0182 | 0.1343 | 0.1343 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0182 | 0.1343 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0182 | 0.1343 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.0182 | 0.1343 | 0.1343 |
Echinococcus multilocularis | acetylcholinesterase | 0.1076 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.1343 | 0.1343 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1076 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.1076 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.1076 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.1343 | 0.1343 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0182 | 0.1343 | 0.1343 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0182 | 0.1343 | 0.5 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0182 | 0.1343 | 0.1343 |
Echinococcus granulosus | neuroligin | 0.0182 | 0.1343 | 0.1343 |
Loa Loa (eye worm) | hypothetical protein | 0.1076 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0182 | 0.1343 | 0.1343 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1076 | 1 | 1 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0182 | 0.1343 | 0.1343 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0182 | 0.1343 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1076 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0182 | 0.1343 | 0.1343 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.1343 | 0.1343 |
Onchocerca volvulus | 0.0182 | 0.1343 | 1 | |
Onchocerca volvulus | 0.0182 | 0.1343 | 1 | |
Loa Loa (eye worm) | carboxylesterase | 0.0182 | 0.1343 | 0.1343 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.1343 | 0.1343 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0182 | 0.1343 | 0.1343 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0182 | 0.1343 | 0.1343 |
Onchocerca volvulus | 0.0182 | 0.1343 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.1343 | 0.1343 |
Onchocerca volvulus | 0.0182 | 0.1343 | 1 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0182 | 0.1343 | 0.1343 |
Loa Loa (eye worm) | carboxylesterase | 0.1076 | 1 | 1 |
Schistosoma mansoni | gliotactin | 0.0182 | 0.1343 | 0.1343 |
Echinococcus granulosus | acetylcholinesterase | 0.1076 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.1076 | 1 | 1 |
Onchocerca volvulus | 0.0182 | 0.1343 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.1343 | 0.1343 |
Brugia malayi | Carboxylesterase family protein | 0.0182 | 0.1343 | 0.1343 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0182 | 0.1343 | 0.5 |
Brugia malayi | hypothetical protein | 0.0182 | 0.1343 | 0.1343 |
Brugia malayi | Carboxylesterase family protein | 0.0182 | 0.1343 | 0.1343 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.1343 | 0.1343 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0182 | 0.1343 | 0.1343 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0182 | 0.1343 | 0.1343 |
Echinococcus granulosus | carboxylesterase 5A | 0.1076 | 1 | 1 |
Echinococcus multilocularis | neuroligin | 0.0182 | 0.1343 | 0.1343 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0182 | 0.1343 | 0.1343 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | = 23 nM | In vitro binding affinity for human Coagulation factor X | ChEMBL. | 12593648 |
Ki (binding) | = 23 nM | Binding affinity for human factor Xa | ChEMBL. | 15999990 |
Ki (binding) | = 23 nM | In vitro binding affinity for human Coagulation factor X | ChEMBL. | 12593648 |
Ki (binding) | = 23 nM | Binding affinity for human factor Xa | ChEMBL. | 15999990 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
2 literature references were collected for this gene.