Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | cannabinoid receptor 1 (brain) | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | endothelin-converting enzyme-related | 0.0214 | 0.0591 | 0.182 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.0648 | 0.2331 | 0.2331 |
Echinococcus multilocularis | endothelin converting enzyme 1 | 0.0877 | 0.3247 | 1 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0214 | 0.0591 | 0.182 |
Loa Loa (eye worm) | hypothetical protein | 0.0664 | 0.2392 | 0.2392 |
Schistosoma mansoni | hypothetical protein | 0.0229 | 0.0652 | 0.2008 |
Loa Loa (eye worm) | zinc metallopeptidase 4 | 0.0214 | 0.0591 | 0.0591 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0877 | 0.3247 | 1 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0292 | 0.0903 | 1 |
Echinococcus granulosus | endothelin converting enzyme 1 | 0.0877 | 0.3247 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0229 | 0.0652 | 0.2008 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0292 | 0.0903 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0648 | 0.2331 | 0.2331 |
Brugia malayi | hypothetical protein | 0.0085 | 0.0076 | 0.0076 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0443 | 0.1508 | 0.4642 |
Loa Loa (eye worm) | hypothetical protein | 0.0648 | 0.2331 | 0.2331 |
Loa Loa (eye worm) | hypothetical protein | 0.0648 | 0.2331 | 0.2331 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0229 | 0.0652 | 0.2008 |
Schistosoma mansoni | hypothetical protein | 0.0229 | 0.0652 | 0.2008 |
Loa Loa (eye worm) | hypothetical protein | 0.0435 | 0.1475 | 0.1475 |
Loa Loa (eye worm) | angiotensin-converting enzyme family protein | 0.2564 | 1 | 1 |
Schistosoma mansoni | neprilysin | 0.0229 | 0.0652 | 0.2008 |
Toxoplasma gondii | peptidase family M13 protein | 0.0877 | 0.3247 | 0.5 |
Schistosoma mansoni | eyes absent homolog | 0.0085 | 0.0076 | 0.0235 |
Brugia malayi | Hypothetical zinc metalloproteinase T16A9.4 | 0.0877 | 0.3247 | 0.3247 |
Loa Loa (eye worm) | hypothetical protein | 0.0877 | 0.3247 | 0.3247 |
Loa Loa (eye worm) | hypothetical protein | 0.0877 | 0.3247 | 0.3247 |
Loa Loa (eye worm) | hypothetical protein | 0.0664 | 0.2392 | 0.2392 |
Schistosoma mansoni | Nep2 peptidase (M13 family) | 0.0443 | 0.1508 | 0.4642 |
Schistosoma mansoni | hypothetical protein | 0.0229 | 0.0652 | 0.2008 |
Brugia malayi | Peptidase family M13 containing protein | 0.0877 | 0.3247 | 0.3247 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0214 | 0.0591 | 0.182 |
Loa Loa (eye worm) | hypothetical protein | 0.0664 | 0.2392 | 0.2392 |
Mycobacterium leprae | probable zinc metalloprotease | 0.0877 | 0.3247 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0664 | 0.2392 | 0.2392 |
Schistosoma mansoni | family M13 non-peptidase homologue (M13 family) | 0.0443 | 0.1508 | 0.4642 |
Brugia malayi | peptidase family M13 containing protein | 0.0214 | 0.0591 | 0.0591 |
Loa Loa (eye worm) | hypothetical protein | 0.0664 | 0.2392 | 0.2392 |
Onchocerca volvulus | 0.0435 | 0.1475 | 0.5 | |
Schistosoma mansoni | family M13 non-peptidase homologue (M13 family) | 0.0214 | 0.0591 | 0.182 |
Loa Loa (eye worm) | hypothetical protein | 0.0648 | 0.2331 | 0.2331 |
Loa Loa (eye worm) | hypothetical protein | 0.0877 | 0.3247 | 0.3247 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.0076 | 0.0076 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0214 | 0.0591 | 0.182 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0292 | 0.0903 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0292 | 0.0903 | 1 |
Mycobacterium tuberculosis | Probable zinc metalloprotease Zmp1 | 0.0877 | 0.3247 | 1 |
Schistosoma mansoni | neprilysin-2 (M13 family) | 0.0443 | 0.1508 | 0.4642 |
Schistosoma mansoni | endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) | 0.0214 | 0.0591 | 0.182 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.0648 | 0.2331 | 0.2331 |
Schistosoma mansoni | hypothetical protein | 0.0229 | 0.0652 | 0.2008 |
Loa Loa (eye worm) | hypothetical protein | 0.0664 | 0.2392 | 0.2392 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.0076 | 0.0076 |
Mycobacterium ulcerans | zinc metalloprotease | 0.0877 | 0.3247 | 1 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0443 | 0.1508 | 0.4642 |
Schistosoma mansoni | hypothetical protein | 0.0229 | 0.0652 | 0.2008 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.