Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | cysteinyl leukotriene receptor 2 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | calcium motive p-type ATPase, putative | 0.0014 | 0.0997 | 1 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0071 | 1 | 1 |
Onchocerca volvulus | 0.0071 | 1 | 1 | |
Toxoplasma gondii | P-type ATPase4, putative | 0.0014 | 0.0997 | 1 |
Echinococcus multilocularis | plasma membrane calcium transporting ATPase | 0.0014 | 0.0997 | 0.022 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0071 | 1 | 1 |
Plasmodium falciparum | non-SERCA-type Ca2+ -transporting P-ATPase | 0.0014 | 0.0997 | 0.5 |
Schistosoma mansoni | Na+/K+ transporting ATPase subunit alpha | 0.0036 | 0.4562 | 0.4093 |
Echinococcus granulosus | nervana 2 | 0.0071 | 1 | 1 |
Schistosoma mansoni | calcium-transporting atpase 2 (atpase 2) | 0.0014 | 0.0997 | 0.022 |
Brugia malayi | Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type | 0.0014 | 0.0997 | 0.2018 |
Echinococcus multilocularis | Tetracycline resistance leader peptide, TetL | 0.0014 | 0.0997 | 0.022 |
Leishmania major | calcium-transporting ATPase, putative | 0.0014 | 0.0997 | 1 |
Entamoeba histolytica | calcium-transporting P-type ATPase, putative | 0.0014 | 0.0997 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0795 | 0.0605 |
Brugia malayi | Probable calcium-transporting ATPase KIAA0703 | 0.0009 | 0.0202 | 0.0238 |
Echinococcus granulosus | calcium transporting atpase | 0.0014 | 0.0997 | 0.022 |
Echinococcus granulosus | Ca2 transporting ATPase plasma membrane | 0.0014 | 0.0997 | 0.022 |
Echinococcus multilocularis | Na+:K+ ATPase alpha subunit | 0.0036 | 0.4562 | 0.4093 |
Schistosoma mansoni | transmemberane protein | 0.0071 | 1 | 1 |
Mycobacterium ulcerans | metal cation transporter p-type ATPase a | 0.0035 | 0.436 | 1 |
Mycobacterium leprae | PROBABLE CATION-TRANSPORTER ATPASE I CTPI | 0.003 | 0.3565 | 0.5 |
Echinococcus multilocularis | sodium:potassium transporting ATPase subunit | 0.0071 | 1 | 1 |
Toxoplasma gondii | plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 | 0.0014 | 0.0997 | 1 |
Brugia malayi | Sodium/potassium-transporting ATPase alpha chain, putative | 0.0031 | 0.3767 | 0.822 |
Trypanosoma cruzi | Calcium ATPase SERCA-like | 0.0013 | 0.0795 | 0.7455 |
Echinococcus multilocularis | nervana 2 | 0.0071 | 1 | 1 |
Entamoeba histolytica | Plasma membrane calcium-transporting ATPase, putative | 0.0013 | 0.0795 | 0.7755 |
Echinococcus granulosus | nervana 2 | 0.0071 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.4562 | 0.445 |
Echinococcus granulosus | plasma membrane calcium transporting ATPase 2 | 0.0014 | 0.0997 | 0.022 |
Loa Loa (eye worm) | Na,K-ATPase alpha subunit | 0.0036 | 0.4562 | 0.445 |
Echinococcus multilocularis | calcium transporting atpase | 0.0014 | 0.0997 | 0.022 |
Giardia lamblia | Potassium-transporting ATPase alpha chain 1 | 0.0036 | 0.4562 | 1 |
Schistosoma mansoni | calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) | 0.0014 | 0.0997 | 0.022 |
Trypanosoma brucei | vacuolar-type Ca2+-ATPase, putative | 0.0013 | 0.0795 | 0.7455 |
Plasmodium vivax | calcium-transporting ATPase, putative | 0.0014 | 0.0997 | 0.5 |
Echinococcus granulosus | nervana 2 | 0.0071 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.2376 | 0.2219 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0014 | 0.0997 | 1 |
Schistosoma mansoni | calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) | 0.0014 | 0.0997 | 0.022 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0014 | 0.0997 | 1 |
Trypanosoma brucei | vacuolar-type Ca2+-ATPase 2 | 0.0013 | 0.0795 | 0.7455 |
Plasmodium vivax | P-type ATPase4, putative | 0.0014 | 0.0997 | 0.5 |
Echinococcus granulosus | plasma membrane calcium transporting ATPase | 0.0014 | 0.0997 | 0.022 |
Trypanosoma cruzi | calcium motive p-type ATPase, putative | 0.0014 | 0.0997 | 1 |
Echinococcus multilocularis | nervana 2 | 0.0071 | 1 | 1 |
Schistosoma mansoni | plasma membrane calcium-transporting atpase | 0.0014 | 0.0997 | 0.022 |
Echinococcus multilocularis | calcium transporting ATPase type 2C member | 0.0014 | 0.0997 | 0.022 |
Trypanosoma cruzi | plasma membrane Ca2+ ATPase | 0.0013 | 0.0795 | 0.7455 |
Plasmodium falciparum | calcium-transporting ATPase | 0.0014 | 0.0997 | 0.5 |
Leishmania major | calcium motive p-type ATPase, putative | 0.0014 | 0.0997 | 1 |
Echinococcus multilocularis | nervana 2 | 0.0071 | 1 | 1 |
Mycobacterium ulcerans | metal cation-transporting p-type ATPase F, CtpF | 0.0014 | 0.0997 | 0.2287 |
Schistosoma mansoni | plasma membrane calcium-transporting atpase | 0.0014 | 0.0997 | 0.022 |
Echinococcus granulosus | calcium transporting ATPase type 2C member | 0.0014 | 0.0997 | 0.022 |
Trypanosoma brucei | vacuolar-type Ca2+-ATPase 1 | 0.0013 | 0.0795 | 0.7455 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.3278 | 0.3139 |
Schistosoma mansoni | sodium/potassium-dependent atpase beta subunit | 0.0071 | 1 | 1 |
Toxoplasma gondii | sarco/endoplasmic reticulum Ca2+-ATPase | 0.0014 | 0.0997 | 1 |
Schistosoma mansoni | na+/k+ atpase alpha subunit | 0.0036 | 0.4562 | 0.4093 |
Mycobacterium tuberculosis | Possible metal cation transporting P-type ATPase CtpH | 0.0008 | 0 | 0.5 |
Brugia malayi | Membrane calcium atpase protein 3 | 0.0014 | 0.0997 | 0.2018 |
Brugia malayi | Na,K-ATPase alpha subunit | 0.0036 | 0.4562 | 1 |
Trypanosoma cruzi | plasma membrane Ca2+ ATPase | 0.0013 | 0.0795 | 0.7455 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0071 | 1 | 1 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0071 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 1 | 1 |
Entamoeba histolytica | Plasma membrane calcium-transporting ATPase, putative | 0.0013 | 0.0795 | 0.7755 |
Echinococcus granulosus | sodium:potassium transporting ATPase subunit | 0.0071 | 1 | 1 |
Entamoeba histolytica | Plasma membrane calcium-transporting ATPase, putative | 0.0013 | 0.0795 | 0.7755 |
Leishmania major | P-type ATPase, putative | 0.0014 | 0.0997 | 1 |
Echinococcus multilocularis | nervana 2 | 0.0071 | 1 | 1 |
Loa Loa (eye worm) | sodium/potassium-transporting ATPase subunit alpha | 0.0031 | 0.3767 | 0.3639 |
Trypanosoma brucei | calcium-translocating P-type ATPase | 0.0014 | 0.0997 | 1 |
Echinococcus granulosus | nervana 2 | 0.0071 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 1 | 1 |
Schistosoma mansoni | sodium / potassium ATPase beta chain | 0.0071 | 1 | 1 |
Trypanosoma cruzi | calcium motive p-type ATPase, putative | 0.0014 | 0.0997 | 1 |
Echinococcus multilocularis | Ca2+ transporting ATPase plasma membrane | 0.0014 | 0.0997 | 0.022 |
Echinococcus granulosus | Na:K ATPase alpha subunit | 0.0036 | 0.4562 | 0.4093 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.2664 | 0.2512 |
Onchocerca volvulus | 0.0071 | 1 | 1 | |
Schistosoma mansoni | sodium/potassium-dependent atpase beta subunit | 0.0071 | 1 | 1 |
Schistosoma mansoni | sodium/potassium-dependent atpase beta subunit | 0.0071 | 1 | 1 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0071 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.