Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | beta-hexosaminidase, putative | 0.02 | 0.0586 | 0.318 |
Trypanosoma cruzi | endo-beta-N-acetylglucosaminidase, putative | 0.0153 | 0 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0261 | 0.1347 | 1 |
Mycobacterium tuberculosis | Probable conserved lipoprotein LpqI | 0.02 | 0.0586 | 0.5 |
Brugia malayi | Alpha-L-fucosidase family protein | 0.058 | 0.5297 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.02 | 0.0586 | 0.318 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0261 | 0.1347 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0261 | 0.1347 | 1 |
Trypanosoma brucei | endo-beta-N-acetylglucosaminidase, putative | 0.0153 | 0 | 0.5 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.0254 | 0.1259 | 0.9211 |
Mycobacterium ulcerans | alpha-L-fucosidase | 0.0959 | 1 | 1 |
Schistosoma mansoni | alpha-l-fucosidase | 0.058 | 0.5297 | 1 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0261 | 0.1347 | 0.2544 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0261 | 0.1347 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0181 | 0.0346 | 0.1027 |
Echinococcus multilocularis | fucosidase, alpha L 1, tissue | 0.0959 | 1 | 1 |
Trichomonas vaginalis | beta-hexosaminidase, putative | 0.02 | 0.0586 | 0.318 |
Mycobacterium leprae | PROBABLE CONSERVED LIPOPROTEIN LPQI | 0.02 | 0.0586 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0261 | 0.1347 | 1 |
Trypanosoma cruzi | endo-beta-N-acetylglucosaminidase, putative | 0.0153 | 0 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0261 | 0.1347 | 1 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0172 | 0.0232 | 0.5 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.0254 | 0.1259 | 0.9211 |
Leishmania major | glycosyl hydrolase-like protein | 0.0153 | 0 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0181 | 0.0346 | 0.1027 |
Loa Loa (eye worm) | alpha-L-fucosidase | 0.058 | 0.5297 | 1 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0261 | 0.1347 | 0.2544 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | 0 % | Percent plasma glucose concentration of drug treated mice (ob/ob) relative to vehicle control animals was determined at the dose of 20 mg/kg; NT=Not tested | ChEMBL. | 1548684 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.