Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0646 | 0.3868 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0646 | 0.3868 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0646 | 0.3868 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0646 | 0.3868 | 0.3868 |
Brugia malayi | Cathepsin L-like precursor | 0.0443 | 0.1231 | 0.1231 |
Loa Loa (eye worm) | ctsf protein | 0.0646 | 0.3868 | 0.3008 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.112 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0446 | 0.1271 | 0.3286 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0646 | 0.3868 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0646 | 0.3868 | 0.3868 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.112 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.112 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.0646 | 0.3868 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.112 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.112 | 1 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0646 | 0.3868 | 0.3868 |
Echinococcus multilocularis | cathepsin b | 0.112 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0646 | 0.3868 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0646 | 0.3868 | 1 |
Echinococcus granulosus | cathepsin b | 0.112 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0646 | 0.3868 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.112 | 1 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0443 | 0.1231 | 0.1231 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0646 | 0.3868 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.0646 | 0.3868 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0646 | 0.3868 | 0.3868 |
Entamoeba histolytica | cysteine protease, putative | 0.0646 | 0.3868 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0646 | 0.3868 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0646 | 0.3868 | 0.3008 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.112 | 1 | 1 |
Onchocerca volvulus | 0.0646 | 0.3868 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0646 | 0.3868 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0446 | 0.1271 | 0.1271 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0646 | 0.3868 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0646 | 0.3868 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0446 | 0.1271 | 0.1271 |
Loa Loa (eye worm) | hypothetical protein | 0.0646 | 0.3868 | 0.3008 |
Brugia malayi | Cathepsin L-like precursor | 0.0646 | 0.3868 | 0.3868 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0646 | 0.3868 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0646 | 0.3868 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0646 | 0.3868 | 0.3868 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0646 | 0.3868 | 0.3868 |
Leishmania major | cathepsin L-like protease | 0.0646 | 0.3868 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0646 | 0.3868 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0443 | 0.1231 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0646 | 0.3868 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0446 | 0.1271 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0646 | 0.3868 | 0.3868 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0646 | 0.3868 | 0.3868 |
Leishmania major | cathepsin L-like protease | 0.0646 | 0.3868 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0646 | 0.3868 | 0.3868 |
Giardia lamblia | Cathepsin B precursor | 0.0446 | 0.1271 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0646 | 0.3868 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0646 | 0.3868 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0646 | 0.3868 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0446 | 0.1271 | 0.3286 |
Onchocerca volvulus | 0.0646 | 0.3868 | 1 | |
Onchocerca volvulus | 0.0646 | 0.3868 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0646 | 0.3868 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0646 | 0.3868 | 0.3008 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0443 | 0.1231 | 0.3182 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0646 | 0.3868 | 0.3868 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0646 | 0.3868 | 1 |
Leishmania major | cathepsin L-like protease | 0.0646 | 0.3868 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0646 | 0.3868 | 0.3868 |
Leishmania major | cathepsin L-like protease | 0.0646 | 0.3868 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0646 | 0.3868 | 1 |
Leishmania major | cathepsin L-like protease | 0.0646 | 0.3868 | 1 |
Loa Loa (eye worm) | cathepsin B | 0.0446 | 0.1271 | 0.0046 |
Brugia malayi | Cathepsin L-like precursor | 0.0646 | 0.3868 | 0.3868 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0646 | 0.3868 | 0.3868 |
Onchocerca volvulus | 0.0646 | 0.3868 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0646 | 0.3868 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0646 | 0.3868 | 0.3868 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0646 | 0.3868 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0646 | 0.3868 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.0646 | 0.3868 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0646 | 0.3868 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0646 | 0.3868 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0646 | 0.3868 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0443 | 0.1231 | 0.1231 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0646 | 0.3868 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0646 | 0.3868 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0443 | 0.1231 | 0.1231 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0646 | 0.3868 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0646 | 0.3868 | 0.3868 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0646 | 0.3868 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0646 | 0.3868 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0646 | 0.3868 | 0.3868 |
Onchocerca volvulus | Cathepsin L homolog | 0.0646 | 0.3868 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0443 | 0.1231 | 0.3182 |
Onchocerca volvulus | 0.0646 | 0.3868 | 1 | |
Loa Loa (eye worm) | fibroinase | 0.0646 | 0.3868 | 0.3008 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0646 | 0.3868 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0646 | 0.3868 | 0.3868 |
Leishmania major | cathepsin L-like protease | 0.0646 | 0.3868 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0646 | 0.3868 | 0.3868 |
Loa Loa (eye worm) | cysteine protease | 0.0646 | 0.3868 | 0.3008 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0646 | 0.3868 | 1 |
Plasmodium vivax | vivapain-2 | 0.0646 | 0.3868 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0646 | 0.3868 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0646 | 0.3868 | 0.3868 |
Giardia lamblia | Cathepsin B precursor | 0.0446 | 0.1271 | 0.5 |
Echinococcus multilocularis | cathepsin b | 0.112 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0646 | 0.3868 | 1 |
Leishmania major | cathepsin L-like protease | 0.0646 | 0.3868 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0646 | 0.3868 | 0.3868 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0646 | 0.3868 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0646 | 0.3868 | 1 |
Leishmania major | cathepsin L-like protease | 0.0646 | 0.3868 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0646 | 0.3868 | 0.3868 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0646 | 0.3868 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0646 | 0.3868 | 0.3868 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0646 | 0.3868 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0443 | 0.1231 | 0.1231 |
Onchocerca volvulus | 0.0646 | 0.3868 | 1 | |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0443 | 0.1231 | 0.1231 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0646 | 0.3868 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0646 | 0.3868 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0443 | 0.1231 | 0.1231 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0646 | 0.3868 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.