Detailed information for compound 34615
Basic information
Technical information
- Name: Unnamed compound
- MW: 340.454 | Formula: C19H32O5
-
H donors: 1
H acceptors: 3
LogP: 5.03
Rotable bonds: 12
Rule of 5 violations (Lipinski): 1 - SMILES: CCCCCCCCCCCC[C@@H]1C(=O)O[C@]2([C@@H]1OC(=O)C2)CO
- InChi: 1S/C19H32O5/c1-2-3-4-5-6-7-8-9-10-11-12-15-17-19(14-20,24-18(15)22)13-16(21)23-17/h15,17,20H,2-14H2,1H3/t15-,17+,19-/m0/s1
- InChiKey: UECAYBNICJTDCT-WDYCEAGBSA-N
Network
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Synonyms
No synonyms found for this compound
Targets
Known targets for this compound
| Species | Target name | Source | Bibliographic reference |
|---|---|---|---|
| Homo sapiens | protein kinase C, alpha | Starlite/ChEMBL | References |
Predicted pathogen targets for this compound
By orthology
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model
Ranking Plot
Putative Targets List
| Species | Potential target | Raw | Global | Species |
|---|---|---|---|---|
| Onchocerca volvulus | 0.0402 | 1 | 0.5 | |
| Brugia malayi | hypothetical protein | 0.0402 | 1 | 1 |
| Schistosoma mansoni | neuropeptide F-like receptor | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Trichomonas vaginalis | AGC family protein kinase | 0.001 | 0.0006 | 1 |
| Echinococcus granulosus | g-protein coupled receptor | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Echinococcus granulosus | histone h3 methyltransferase | 0.0129 | 0.3025 | 0.3021 |
| Onchocerca volvulus | 0.0402 | 1 | 0.5 | |
| Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.1143 | 0.1138 |
| Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0402 | 1 | 1 |
| Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | somatostatin receptor | 0.0402 | 1 | 1 |
| Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | neuropeptides capa receptor | 0.0402 | 1 | 1 |
| Echinococcus granulosus | RNA directed DNA polymerase | 0.0048 | 0.0957 | 0.0952 |
| Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0402 | 1 | 1 |
| Echinococcus granulosus | rhodopsin orphan GPCR | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0402 | 1 | 1 |
| Leishmania major | hypothetical protein, conserved | 0.0016 | 0.0159 | 0.5 |
| Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0402 | 1 | 1 |
| Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0402 | 1 | 1 |
| Echinococcus granulosus | g protein coupled receptor | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | G-protein coupled receptor | 0.0402 | 1 | 1 |
| Echinococcus granulosus | dro:myosuppressin receptor | 0.0402 | 1 | 1 |
| Brugia malayi | hypothetical protein | 0.0061 | 0.129 | 0.1285 |
| Loa Loa (eye worm) | melatonin receptor type 1A | 0.0402 | 1 | 1 |
| Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0402 | 1 | 1 |
| Echinococcus granulosus | g protein coupled receptor | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | neuropeptide F receptor | 0.0402 | 1 | 1 |
| Schistosoma mansoni | neuropeptide receptor | 0.0402 | 1 | 1 |
| Echinococcus granulosus | neuropeptide receptor | 0.0402 | 1 | 1 |
| Schistosoma mansoni | protein kinase | 0.0071 | 0.1562 | 0.1557 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0402 | 1 | 1 |
| Schistosoma mansoni | neuropeptide receptor | 0.0402 | 1 | 1 |
| Trichomonas vaginalis | AGC family protein kinase | 0.001 | 0.0006 | 1 |
| Loa Loa (eye worm) | TKL/STKR/TYPE1 protein kinase | 0.0072 | 0.1583 | 0.1578 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Schistosoma mansoni | histone J3 methyltransferase | 0.0129 | 0.3025 | 0.3021 |
| Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0402 | 1 | 1 |
| Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0402 | 1 | 1 |
| Onchocerca volvulus | 0.0402 | 1 | 0.5 | |
| Echinococcus multilocularis | dro:myosuppressin receptor | 0.0402 | 1 | 1 |
| Schistosoma mansoni | biogenic amine receptor | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | fmrfamide receptor | 0.0402 | 1 | 1 |
| Trichomonas vaginalis | AGC family protein kinase | 0.001 | 0.0006 | 1 |
| Leishmania major | hypothetical protein, conserved | 0.0016 | 0.0159 | 0.5 |
| Echinococcus granulosus | rhodopsin orphan GPCR | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | protein kinase c epsilon type | 0.0019 | 0.0231 | 0.0225 |
| Echinococcus granulosus | activin receptor type | 0.0072 | 0.1589 | 0.1584 |
| Echinococcus multilocularis | RNA directed DNA polymerase | 0.0048 | 0.0957 | 0.0952 |
| Schistosoma mansoni | serine/threonine protein kinase | 0.0067 | 0.1445 | 0.144 |
| Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0402 | 1 | 1 |
| Schistosoma mansoni | histamine h1 receptor | 0.0402 | 1 | 1 |
| Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | histone h3 methyltransferase | 0.0129 | 0.3025 | 0.3021 |
| Brugia malayi | Melatonin receptor type 1A | 0.0402 | 1 | 1 |
| Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0402 | 1 | 1 |
| Brugia malayi | protein kinase C II. | 0.0019 | 0.0231 | 0.0225 |
| Trypanosoma cruzi | Histone-lysine N-methyltransferase, H3 lysine-76 specific | 0.0016 | 0.0159 | 0.5 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Onchocerca volvulus | 0.0402 | 1 | 0.5 | |
| Echinococcus granulosus | neuropeptide receptor | 0.0402 | 1 | 1 |
| Schistosoma mansoni | amine GPCR | 0.0402 | 1 | 1 |
| Brugia malayi | hypothetical protein | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0067 | 0.1445 | 0.144 |
| Trichomonas vaginalis | AGC family protein kinase | 0.001 | 0.0006 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Echinococcus granulosus | TGF beta receptor type 1 | 0.0071 | 0.1562 | 0.1557 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Echinococcus granulosus | tm gpcr rhodopsin | 0.0402 | 1 | 1 |
| Schistosoma mansoni | neuropeptide f receptor 76f | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Echinococcus granulosus | rhodopsin orphan GPCR | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | G-protein coupled receptor | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Echinococcus granulosus | neuropeptides capa receptor | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0402 | 1 | 1 |
| Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0402 | 1 | 1 |
| Trypanosoma cruzi | Histone methylation protein DOT1, putative | 0.0016 | 0.0159 | 0.5 |
| Echinococcus multilocularis | neuropeptide receptor A26 | 0.0402 | 1 | 1 |
| Brugia malayi | follicle stimulating hormone receptor | 0.0402 | 1 | 1 |
| Brugia malayi | Histone-lysine N-methyltransferase, H3 lysine-79 specific | 0.0129 | 0.3025 | 0.3021 |
| Schistosoma mansoni | opsin-like receptor | 0.0402 | 1 | 1 |
| Trichomonas vaginalis | AGC family protein kinase | 0.001 | 0.0006 | 1 |
| Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0402 | 1 | 1 |
| Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0402 | 1 | 1 |
| Entamoeba histolytica | protein kinase, putative | 0.001 | 0.0006 | 0.5 |
| Echinococcus multilocularis | sex peptide receptor | 0.0402 | 1 | 1 |
| Onchocerca volvulus | 0.0402 | 1 | 0.5 | |
| Schistosoma mansoni | amine GPCR | 0.0402 | 1 | 1 |
| Onchocerca volvulus | 0.0402 | 1 | 0.5 | |
| Echinococcus multilocularis | g protein coupled receptor | 0.0402 | 1 | 1 |
| Brugia malayi | Dopamine receptor protein 2 | 0.0402 | 1 | 1 |
| Onchocerca volvulus | 0.0402 | 1 | 0.5 | |
| Echinococcus granulosus | serotonin receptor | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | g-protein coupled receptor | 0.0402 | 1 | 1 |
| Brugia malayi | hypothetical protein | 0.0402 | 1 | 1 |
| Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | TYRA-2 protein | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | orexin receptor type 2 | 0.0402 | 1 | 1 |
| Schistosoma mansoni | neuropeptide receptor | 0.0402 | 1 | 1 |
| Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0402 | 1 | 1 |
| Onchocerca volvulus | 0.0402 | 1 | 0.5 | |
| Leishmania major | histone-lysine N-methyltransferase, putative | 0.0016 | 0.0159 | 0.5 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Brugia malayi | sulfakinin receptor protein | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0402 | 1 | 1 |
| Trypanosoma cruzi | Histone methylation protein DOT1, putative | 0.0016 | 0.0159 | 0.5 |
| Onchocerca volvulus | 0.0402 | 1 | 0.5 | |
| Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0402 | 1 | 1 |
| Onchocerca volvulus | 0.0402 | 1 | 0.5 | |
| Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0019 | 0.0231 | 0.0225 |
| Brugia malayi | bone morphogenetic protein type 1 receptor | 0.0072 | 0.1583 | 0.1578 |
| Echinococcus granulosus | hypothetical protein | 0.0402 | 1 | 1 |
| Echinococcus granulosus | G protein coupled receptor 139 | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0402 | 1 | 1 |
| Trichomonas vaginalis | AGC family protein kinase | 0.001 | 0.0006 | 1 |
| Echinococcus granulosus | neuropeptide s receptor | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | activin receptor type | 0.0072 | 0.1589 | 0.1584 |
| Echinococcus multilocularis | g protein coupled receptor | 0.0402 | 1 | 1 |
| Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0402 | 1 | 1 |
| Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0402 | 1 | 1 |
| Echinococcus granulosus | rhodopsin orphan GPCR | 0.0402 | 1 | 1 |
| Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0402 | 1 | 1 |
| Brugia malayi | hypothetical protein | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Brugia malayi | larval opioid receptor | 0.0402 | 1 | 1 |
| Brugia malayi | ORL1-like opioid receptor | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | serine threonine protein kinase | 0.0059 | 0.1259 | 0.1254 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0402 | 1 | 1 |
| Trichomonas vaginalis | AGC family protein kinase | 0.001 | 0.0006 | 1 |
| Schistosoma mansoni | amine GPCR | 0.0402 | 1 | 1 |
| Schistosoma mansoni | opsin-like receptor | 0.0402 | 1 | 1 |
| Brugia malayi | neuropeptide F receptor | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | neuropeptide receptor | 0.0402 | 1 | 1 |
| Echinococcus granulosus | neuropeptide Y receptor | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0402 | 1 | 1 |
| Echinococcus granulosus | neuropeptide Y receptor | 0.0402 | 1 | 1 |
| Onchocerca volvulus | 0.0402 | 1 | 0.5 | |
| Brugia malayi | G-protein coupled receptor | 0.0402 | 1 | 1 |
| Trypanosoma brucei | histone-lysine n-methyltransferase | 0.0016 | 0.0159 | 1 |
| Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0402 | 1 | 1 |
| Trichomonas vaginalis | AGC family protein kinase | 0.001 | 0.0006 | 1 |
| Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0402 | 1 | 1 |
| Echinococcus granulosus | protein kinase c iota type | 0.0018 | 0.0192 | 0.0186 |
| Echinococcus multilocularis | allatostatin A receptor | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0402 | 1 | 1 |
| Echinococcus granulosus | tm gpcr rhodopsin | 0.0402 | 1 | 1 |
| Brugia malayi | Protein kinase c protein 2 | 0.0057 | 0.1187 | 0.1182 |
| Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | neuropeptide s receptor | 0.0402 | 1 | 1 |
| Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0402 | 1 | 1 |
| Brugia malayi | AKH receptor | 0.0402 | 1 | 1 |
| Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0402 | 1 | 1 |
| Echinococcus granulosus | rhodopsin orphan GPCR | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | neuropeptide Y receptor | 0.0402 | 1 | 1 |
| Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0402 | 1 | 1 |
| Schistosoma mansoni | amine GPCR | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Brugia malayi | hypothetical protein | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Entamoeba histolytica | protein kinase, putative | 0.001 | 0.0006 | 0.5 |
| Schistosoma mansoni | opsin-like receptor | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.0049 | 0.1001 | 0.0996 |
| Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0957 | 0.0952 |
| Brugia malayi | putative neuropeptide receptor NPR1 | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | g protein coupled receptor | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | TGF beta receptor type 1 | 0.0071 | 0.1562 | 0.1557 |
| Echinococcus granulosus | fmrfamide receptor | 0.0402 | 1 | 1 |
| Trichomonas vaginalis | AGC family protein kinase | 0.001 | 0.0006 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | TKL/STKR/TYPE1 protein kinase | 0.0267 | 0.6546 | 0.6544 |
| Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0402 | 1 | 1 |
| Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0402 | 1 | 1 |
| Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Echinococcus granulosus | sex peptide receptor | 0.0402 | 1 | 1 |
| Echinococcus granulosus | protein kinase C gamma type | 0.0059 | 0.1259 | 0.1254 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Brugia malayi | G protein-coupled receptor | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Echinococcus granulosus | orexin receptor type 2 | 0.0402 | 1 | 1 |
| Trichomonas vaginalis | AGC family protein kinase | 0.001 | 0.0006 | 1 |
| Echinococcus multilocularis | G protein coupled receptor 139 | 0.0402 | 1 | 1 |
| Echinococcus granulosus | rhodopsin orphan GPCR | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Schistosoma mansoni | serine/threonine protein kinase | 0.0067 | 0.1445 | 0.144 |
| Brugia malayi | RE15519p | 0.0402 | 1 | 1 |
| Schistosoma mansoni | hypothetical protein | 0.0402 | 1 | 1 |
| Brugia malayi | hypothetical protein | 0.0402 | 1 | 1 |
| Onchocerca volvulus | 0.0402 | 1 | 0.5 | |
| Echinococcus granulosus | Protein kinase C brain isozyme | 0.0067 | 0.1445 | 0.144 |
| Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0402 | 1 | 1 |
| Schistosoma mansoni | amine GPCR | 0.0402 | 1 | 1 |
| Echinococcus granulosus | biogenic amine 5HT receptor | 0.0402 | 1 | 1 |
| Echinococcus granulosus | g protein coupled receptor | 0.0402 | 1 | 1 |
| Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Brugia malayi | protein C17H12.11 | 0.0061 | 0.129 | 0.1285 |
| Echinococcus granulosus | tm gpcr rhodopsin | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.129 | 0.1285 |
| Schistosoma mansoni | serine/threonine protein kinase | 0.0019 | 0.0231 | 0.0225 |
| Loa Loa (eye worm) | neuropeptide F receptor | 0.0402 | 1 | 1 |
| Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0402 | 1 | 1 |
| Toxoplasma gondii | hypothetical protein | 0.0016 | 0.0159 | 1 |
| Brugia malayi | neuropeptide F receptor | 0.0402 | 1 | 1 |
| Schistosoma mansoni | biogenic amine receptor | 0.0402 | 1 | 1 |
| Echinococcus granulosus | protein kinase c epsilon type | 0.0019 | 0.0231 | 0.0225 |
| Onchocerca volvulus | 0.0402 | 1 | 0.5 | |
| Brugia malayi | Protein kinase domain containing protein | 0.0267 | 0.6546 | 0.6544 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | neuropeptides capa receptor | 0.0402 | 1 | 1 |
| Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0402 | 1 | 1 |
| Brugia malayi | hypothetical protein | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0402 | 1 | 1 |
| Onchocerca volvulus | 0.0402 | 1 | 0.5 | |
| Brugia malayi | hypothetical protein | 0.0402 | 1 | 1 |
| Brugia malayi | Serotonin receptor | 0.0402 | 1 | 1 |
| Brugia malayi | GnHR receptor homolog | 0.0402 | 1 | 1 |
| Trypanosoma brucei | Histone-lysine N-methyltransferase, H3 lysine-76 specific | 0.0016 | 0.0159 | 1 |
| Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.0048 | 0.0957 | 0.0952 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0402 | 1 | 1 |
| Schistosoma mansoni | atypical protein kinase C | 0.0018 | 0.0192 | 0.0186 |
| Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0402 | 1 | 1 |
| Brugia malayi | hypothetical protein | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Entamoeba histolytica | protein kinase, putative | 0.001 | 0.0006 | 0.5 |
| Loa Loa (eye worm) | hypothetical protein | 0.0129 | 0.3025 | 0.3021 |
| Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0402 | 1 | 1 |
| Schistosoma mansoni | biogenic amine receptor | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Trypanosoma brucei | Histone methylation protein DOT1, putative | 0.0016 | 0.0159 | 1 |
| Onchocerca volvulus | 0.0402 | 1 | 0.5 | |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Entamoeba histolytica | protein kinase, putative | 0.001 | 0.0006 | 0.5 |
| Onchocerca volvulus | 0.0402 | 1 | 0.5 | |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | fmrfamide receptor | 0.0402 | 1 | 1 |
| Schistosoma mansoni | neuropeptide receptor | 0.0402 | 1 | 1 |
| Echinococcus granulosus | rhodopsin orphan GPCR | 0.0402 | 1 | 1 |
| Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0402 | 1 | 1 |
| Trypanosoma cruzi | histone-lysine N-methyltransferase, putative | 0.0016 | 0.0159 | 0.5 |
| Brugia malayi | Serotonin receptor | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | TKL/STKR/TYPE2 protein kinase | 0.0061 | 0.1295 | 0.129 |
| Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | protein kinase c iota type | 0.0018 | 0.0192 | 0.0186 |
| Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0402 | 1 | 1 |
| Echinococcus granulosus | neuropeptide receptor A26 | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | neuropeptide Y receptor | 0.0402 | 1 | 1 |
| Schistosoma mansoni | protein kinase | 0.0072 | 0.1583 | 0.1578 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0402 | 1 | 1 |
| Schistosoma mansoni | growth hormone secretagogue receptor | 0.0402 | 1 | 1 |
| Schistosoma mansoni | hypothetical protein | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0402 | 1 | 1 |
| Brugia malayi | putative neuropeptide receptor | 0.0402 | 1 | 1 |
| Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Brugia malayi | G-protein coupled receptor | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | neuropeptide receptor | 0.0402 | 1 | 1 |
| Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0402 | 1 | 1 |
| Echinococcus granulosus | somatostatin receptor | 0.0402 | 1 | 1 |
| Brugia malayi | Dopamine receptor | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0402 | 1 | 1 |
| Schistosoma mansoni | hypothetical protein | 0.0402 | 1 | 1 |
| Echinococcus granulosus | neuropeptides capa receptor | 0.0402 | 1 | 1 |
| Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0402 | 1 | 1 |
| Schistosoma mansoni | hypothetical protein | 0.0402 | 1 | 1 |
| Onchocerca volvulus | 0.0402 | 1 | 0.5 | |
| Echinococcus granulosus | 7tm_1 domain containing protein | 0.0402 | 1 | 1 |
| Echinococcus granulosus | TGF-beta receptor type-1 | 0.0071 | 0.1562 | 0.1557 |
| Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0402 | 1 | 0.5 |
| Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0402 | 1 | 1 |
| Brugia malayi | Dopamine receptor protein 1 | 0.0402 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0402 | 1 | 1 |
| Trichomonas vaginalis | AGC family protein kinase | 0.001 | 0.0006 | 1 |
| Echinococcus granulosus | allatostatin A receptor | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | serotonin receptor | 0.0402 | 1 | 1 |
| Schistosoma mansoni | adenoreceptor | 0.0402 | 1 | 1 |
| Schistosoma mansoni | neuropeptide F-like receptor | 0.0402 | 1 | 1 |
| Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0402 | 1 | 0.5 |
| Loa Loa (eye worm) | hypothetical protein | 0.0402 | 1 | 1 |
| Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | serotonin receptor | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0402 | 1 | 1 |
| Echinococcus granulosus | biogenic amine 5HT receptor | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0402 | 1 | 1 |
| Echinococcus multilocularis | serine:threonine protein kinase receptor R3 | 0.0071 | 0.1562 | 0.1557 |
| Schistosoma mansoni | myosin xvIII | 0.0402 | 1 | 1 |
| Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0402 | 1 | 1 |
Activities
Phenotypes
Whole-cell/tissue/organism interactions
We have no records of whole-cell/tissue assays done with this compound
What does this mean?
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
Annotated phenotypes:
We have no manually annotated phenotypes for this drug.
What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by
drugs, or by genetic manipulation of cells (e.g. gene knockouts or
knockdowns) is manually curated from the literature. These
descriptions help to describe the potential of the target for drug
development. If no information is available for this gene or if the
information is incomplete, this may mean that i) the papers
containing this information either appeared after the curation
effort for this organism was carried out or they were inadvertently
missed by curators; or that ii) the curation effort for this
organism has not yet started.
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.
External resources for this compound
No external resources registered for this compound
Bibliographic References
1 literature reference was collected for this gene.
If you have references for this compound, please enter them in a user comment (below) or Contact us.